Achieva 3t tx system

Manufactured by Philips

Sourced in Netherlands

The Philips Achieva 3T TX system is a magnetic resonance imaging (MRI) scanner that operates at a static magnetic field strength of 3 tesla. It is designed to provide high-quality imaging for a variety of clinical and research applications.

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Lab products found in correlation

Ingenia 3 t system, by Philips (4 mentions) 32 channel cardiac phased array receiver coil, by Philips (1 mentions) Matlab, by MathWorks (1 mentions) Mammotrak, by Philips (1 mentions) Multihance, by Bracco (1 mentions)

9 protocols using achieva 3t tx system

Perfusion Quantification Accuracy Evaluation

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In the first set of experiments, we used synthetic data to demonstrate the sensitivity of deconvolution and MBF estimation to the delay time between t_AIF and t_Onset.
Then we tested the accuracy of the t_Onset detection algorithm and validated it against gold standard perfusion measurements using an MR-compatible perfusion phantom.
In both experiments, we evaluated the impact of CNR on the detection of the onset arrival time and, thus, on the accuracy of perfusion estimates. For this purpose, the original data were corrupted by adding Rician noise of variable amplitudes to both C_aif (t) and C_tiss(t) [12 (link)], [13 (link)]. The range of noise amplitude was chosen so that CNR in the both C_aif (t) and C_tiss(t) would be between 5 and 40. Equal noise amplitudes were added to both C_aif (t) and C_tiss(t) at each CNR level.
Finally, we compared the results of voxel-wise and segmental analysis performed with optimized t_Onset with the results obtained from considering t_Onset a free global parameter in phantom and in vivo.
All the analyses described in this study were performed using house-made software programmed with MATLAB (Mathworks, Natick, MA, USA, version R2010b). All data (phantom and patient) were acquired on a Philips Achieva 3T (TX) system, equipped with a 32-channel cardiac-phased array receiver coil (Philips Healthcare, Best, The Netherlands).

Zarinabad N., Hautvast G.L., Sammut E., Arujuna A., Breeuwer M., Nagel E, & Chiribiri A. (2014). Effects of Tracer Arrival Time on the Accuracy of High-Resolution (Voxel-Wise) Myocardial Perfusion Maps from Contrast-Enhanced First-Pass Perfusion Magnetic Resonance. IEEE transactions on bio-medical engineering, 61(9), 2499-2506.

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Diffusion MRI Acquisition Protocol for Healthy Volunteers

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Diffusion MRI data were acquired on a Philips Achieva 3T TX system (Philips Healthcare, Best, the Netherlands), equipped with 80 mT/m gradients and a 32‐element receive head coil array, using a diffusion‐weighted single‐shot spin echo EPI sequence. The study was approved by the local ethics committee and meets the guidelines of the declaration of Helsinki. Written informed consent was obtained from all subjects.
Data sets from 16 healthy volunteers (age: 31.6 ± 8.6, gender: 12 male, 4 female) were acquired with the following diffusion scan parameters: TR: 11.85 s, TE: 66 ms, FOV: 220 × 220 mm², with 40 contiguous slices, slice thickness: 2.3 mm, acquisition and reconstruction matrix: 96 × 96, SENSE factor: 2, partial Fourier encoding: 60%. Diffusion‐weighted images were acquired along 64 directions distributed uniformly on a half‐sphere with a b‐value of 3000 s/mm² in addition to a b = 0 s/mm² scan, resulting in a scan time of approximately 13 min. Additionally, 1 mm isotropic T1‐weighted structural images were recorded with a 3D MP‐RAGE sequence (FOV: 240 × 240 × 160 mm³, sagittal orientation, 1 × 1 × 1 mm³ voxel size, TR: 8.14 ms, TE: 3.7 ms, flip angle: 8°).

Sommer S., Kozerke S., Seifritz E, & Staempfli P. (2016). Fiber up‐sampling and quality assessment of tractograms – towards quantitative brain connectivity. Brain and Behavior, 7(1), e00588.

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Ultrafast Breast DCE-MRI Acquisition Protocol

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DCE-MRI was performed with an Achieva 3 T-TX system (Philips Healthcare) and 16-channel bilateral breast coils (MammoTrak, Philips Healthcare). The ultrafast acquisition was a T1-weighted fat-suppressed sequence with an increased SENSE factor, reduced spatial resolution, and very high temporal resolution (7 seconds). The acquisition parameters for ultrafast and standard imaging are summarized in Table 2. The DCE series consisted of one standard and five ultrafast acquisitions before contrast injection and then eight ultrafast and four standard acquisitions after injection of gadobenate dimeglumine (MultiHance, Bracco) at a dose of 0.1 mM/kg and a rate of 2 mL/s followed by a 20-mL saline flush at a rate of 2 mL/s. We obtained five unenhanced images purely for research purposes; the last (5th) unenhanced image was used for the subtraction mask. Acquisition of the ultrafast contrast-enhanced series started 10 seconds after the beginning of contrast injection and ended 66 seconds after the beginning of the injection. The standard acquisition started immediately after completion of the ultrafast acquisition and ended 5 minutes 26 seconds after the beginning of the contrast injection. Figure 1 shows the ultrafast and standard imaging protocols.

Abe H., Mori N., Tsuchiya K., Schacht D.V., Pineda F.D., Jiang Y, & Karczmar G.S. (2016). Kinetic Analysis of Benign and Malignant Breast Lesions With Ultrafast Dynamic Contrast-Enhanced MRI: Comparison With Standard Kinetic Assessment. AJR. American journal of roentgenology, 207(5), 1159-1166.

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Optimized 31P/1H MRI Brain Imaging Protocol

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All data were acquired on a Philips Achieva 3 T TX system (Best, Netherlands). Volunteer and phantom scans were conducted solely using a dual-tuned ³¹P/¹H head coil (Rapid Biomedical, Germany). Parameters for the final acquisition protocol used in patients were optimised using a combination of phantoms and volunteers.
Patient data were acquired using a combination of both the ³¹P/¹H head coil and a 32 channel ¹H Philips head coil. Standard imaging was performed using the 32 channel ¹H head coil or the neurovascular coil. Basic localiser imaging and ³¹P spectroscopy was performed using the ³¹P/¹H head coil.

Novak J., Wilson M., MacPherson L., Arvanitis T.N., Davies N.P, & Peet A.C. (2014). Clinical protocols for 31P MRS of the brain and their use in evaluating optic pathway gliomas in children. European Journal of Radiology, 83(2), e106-e112.

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Harmonized MRI Acquisition for Preterm and Full-Term Infants

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MRI data acquisition has been described previously⁴, ²³: At both sites, Bonn and Munich, MRI data acquisition was performed on Philips Achieva 3 T TX systems or Philips Ingenia 3 T system using an 8‐channel SENSE head coil. Subject distribution among scanners was as follows: Bonn Achieva 3 T: 5 VP/VLBW, 12 FT, Bonn Ingenia 3 T: 33 VP/VLBW, 17 FT, Munich Achieva 3 T: 60 VP/VLBW, 65 FT, Munich Ingenia 3 T: 3 VP/VLBW, 17 FT. Across all scanners, sequence parameters were kept identical. Scanners were checked regularly to provide optimal scanning conditions and MRI physicists at the University Hospital Bonn and Klinikum rechts der Isar regularly scanned imaging phantoms to ensure within‐scanner signal stability over time. Signal‐to‐noise ratio was not significantly different between scanners (one‐way ANOVA with factor ‘scanner‐ID’ [Bonn 1, Bonn 2, Munich 1, Munich 2]; F(3,182) = 1.84, p = 0.11). A high‐resolution T1w 3D‐MPRAGE sequence (TI = 1300 ms, TR = 7.7 ms, TE = 3.9 ms, flip angle = 15°, field of view = 256 mm × 256 mm, reconstruction matrix = 256 × 256, reconstructed isotropic voxel size = 1 mm³) was acquired. All images were visually inspected for artifacts.

Schmitz‐Koep B., Menegaux A., Zimmermann J., Thalhammer M., Neubauer A., Wendt J., Schinz D., Daamen M., Boecker H., Zimmer C., Priller J., Wolke D., Bartmann P., Sorg C, & Hedderich D.M. (2023). Altered gray‐to‐white matter tissue contrast in preterm‐born adults. CNS Neuroscience & Therapeutics, 29(11), 3199-3211.

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Cross-site Brain Imaging Protocol with Scanner Upgrade

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At both sites, MR data were initially acquired on identical Philips Achieva 3 T TX systems (Philips, Best, Netherlands), using 8-channel SENSE head coils. Due to a scanner upgrade, Bonn had to switch to a complementary Philips Ingenia 3 T system after n = 15 participants, while Munich had to do the same switch after n = 105 participants (Supplementary Table 1). Yet, the identical sequence parameters were used on all scanners. To account for possible confounds introduced by the scanner-specific differences, all second-level functional data analyses included dummy regressors for scanner identity as covariates of no interest.
During each run, 215 T2*-weighted EPI volumes were acquired (TR = 2000 ms, TE = 35 ms, flip angle = 82°, parallel imaging with SENSE = 2 (A − P); 32 interleaved oblique axial slices with a slice thickness = 4 mm (no gap); field of view = 220 × 220 × 128 mm; reconstruction matrix = 96 × 96; reconstructed voxel size = 2.29 × 2.29 × 4 mm). Five additional dummy scans were acquired (to achieve longitudinal magnetization equilibrium), but were already discarded before image reconstruction. For image registration purposes, high-resolution T1-weighted 3D-MPRAGE volumes were acquired (TI = 1300 ms, TR = 7.7 ms, TE = 3.9 ms, flip angle = 15°; 180 sagittal slices, field of view: 256 × 256 mm, reconstructed voxel size = 1³ mm³).

Daamen M., Bäuml J.G., Scheef L., Meng C., Jurcoane A., Jaekel J., Sorg C., Busch B., Baumann N., Bartmann P., Wolke D., Wohlschläger A, & Boecker H. (2015). Neural correlates of executive attention in adults born very preterm. NeuroImage : Clinical, 9, 581-591.

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Multisite MRI Neuroimaging Protocol

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At both sites, Bonn and Munich, MRI data acquisition was performed on Philips Achieva 3 T TX systems or Philips Ingenia 3 T system using an 8‐channel SENSE head coil. Subject distribution among scanners: Bonn Achieva 3 T: 5 VP/VLBW, 12 FT, Bonn Ingenia 3 T: 33 VP/VLBW, 17 FT, Munich Achieva 3 T: 60 VP/VLBW, 65 FT, Munich Ingenia 3 T: 3 VP/VLBW, 17 FT. To account for possible confounds by scanner differences, functional and structural data analyses included scanner dummy‐variables as covariates of no interest. Across all scanners, sequence parameters were kept identical. Scanners were checked regularly to provide optimal scanning conditions and MRI physicists at the University Hospital Bonn and Klinikum rechts der Isar regularly scanned imaging phantoms, to ensure within‐scanner signal stability over time. Signal‐to‐noise ratio was not significantly different between scanners (one‐way analysis of variance with factor “scanner‐ID” [Bonn 1, Bonn 2, Munich 1, Munich 2]; F(3,182) = 1.84, p = .11). A high‐resolution T1‐weighted 3D‐MPRAGE sequence (TI = 1,300 ms, TR = 7.7 ms, TE = 3.9 ms, flip angle = 15°; 180 sagittal slices, FOV = 256 × 256 × 180 mm, reconstruction matrix = 256 × 256; reconstructed isotropic voxel size = 1 mm³) was acquired. All images were visually inspected for artifacts and passed homogeneity control implemented in the CAT12 toolbox (Gaser & Dahnke, 2016).

Schmitz‐Koep B., Bäuml J.G., Menegaux A., Nuttall R., Zimmermann J., Schneider S.C., Daamen M., Scheef L., Boecker H., Zimmer C., Gaser C., Wolke D., Bartmann P., Sorg C, & Hedderich D.M. (2020). Decreased cortical thickness mediates the relationship between premature birth and cognitive performance in adulthood. Human Brain Mapping, 41(17), 4952-4963.

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High-Resolution T1-Weighted MRI Acquisition

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MRI data acquisition has been described previously:^{12 (link),22 (link)} at both sites, Bonn and Munich, MRI data acquisition was performed on Philips Achieva 3T TX systems or Philips Ingenia 3T systems using an eight-channel SENSE head coil. Subject distribution among scanners: Bonn Achieva 3T: 5 VP/VLBW, 12 FT, Bonn Ingenia 3T: 33 VP/VLBW, 17 FT, Munich Achieva 3T: 60 VP/VLBW, 65 FT, Munich Ingenia 3T: 3 VP/VLBW, 17 FT. Across all scanners, sequence parameters were kept identical. Scanners were checked regularly to provide optimal scanning conditions and MRI physicists at the University Hospital Bonn and Klinikum Rechts der Isar regularly scanned imaging phantoms, to ensure within-scanner signal stability over time. The signal-to-noise ratio was not significantly different between scanners [one-way ANOVA with factor ‘Scanner-ID’ (Bonn 1, Bonn 2, Munich 1, Munich 2); F (3,182) = 1.84, P = 0.11]. A high-resolution T₁-weighted 3D-magnetization prepared rapid acquisition gradient echo sequence (inversion time = 1300 ms, repetition time = 7.7 ms, echo time = 3.9 ms, flip angle = 15°, field of view = 256 mm × 256 mm, reconstruction matrix = 256 × 256 and reconstructed isotropic voxel size = 1 mm³) was acquired. All images were visually inspected for artefacts.

Schmitz-Koep B., Menegaux A., Zimmermann J., Thalhammer M., Neubauer A., Wendt J., Schinz D., Wachinger C., Daamen M., Boecker H., Zimmer C., Priller J., Wolke D., Bartmann P., Sorg C, & Hedderich D.M. (2022). Aberrant allometric scaling of cortical folding in preterm-born adults. Brain Communications, 5(1), fcac341.

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Standardized 3T MRI Data Acquisition

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At both sites, MRI data acquisition was initially performed on Philips Achieva 3T TX systems (Achieva, Philips, the Netherlands), using an 8-channel SENSE head coil. Due to a scanner upgrade, data acquisition in Bonn had to switch to Philips Ingenia 3T system with an 8-channel SENSE head coil after N = 17 participants. To account for possible confounds introduced by scanner differences, data analyses included scanner identities as covariates of no interest. Across all scanners, sequence parameters were kept identical. Scanners were checked regularly to provide optimal scanning conditions. Signal-to-noise ratio (SNR) was not significantly different between scanners (one-way ANOVA with factor "scanner-ID" [Bonn 1, Bonn 2, Munich]; P = 0.811). A high-resolution T1-weighted 3D-MPRAGE sequence (TI = 1300 ms, TR = 7.7 ms, TE = 3.9 ms, flip angle = 15°; 180 sagittal slices, FOV = 256 × 256 × 180 mm, reconstruction matrix = 256 × 256; reconstructed voxel size = 1 × 1 × 1 mm3) was acquired.

Grothe M.J., Scheef L., Bäuml J., Meng C., Daamen M., Baumann N., Zimmer C., Teipel S., Bartmann P., Boecker H., Wolke D., Wohlschläger A, & Sorg C. (2017). Reduced Cholinergic Basal Forebrain Integrity Links Neonatal Complications and Adult Cognitive Deficits After Premature Birth. Biological psychiatry, 82(2).

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