Sense flex m

Manufactured by Philips

SENSE-flex-M is a laboratory equipment product from Philips. It is designed to perform specific functions in a laboratory setting. The core function of the SENSE-flex-M is to enable precise and reliable measurements, but a detailed description of its intended use or additional features is not available.

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Lab products found in correlation

Achieva 3.0t, by Philips (1 mentions)

Close spelling variants of this product

SENSE-Flex-M coil

4 protocols using sense flex m

Relaxivity Measurement of Gd-BnDOTA Conjugates

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Stock solutions of 5 mM G5–Gd-BnDOTA conjugates were serially diluted to concentrations of 0.125 to 0.500 mM with PBS, pH 7.4. Relaxivity measurements were performed using a previous protocol [17 (link)] at ∼22°C using a 3-Tesla clinical scanner (Achieva 3.0 T, Philips Medical System, The Netherlands) using a manufacturer-supplied surface receiver coil (SENSE-Flex-M). A series of single slice 2D inversion recovery (IR) turbo spin echo images of the solutions were acquired with an acceleration factor of 8, an effective TE around 34 ms, and inversion recovery times (TI = 50, 100, 350, 750, 1250, 2500 and 5000 ms). The R₁ values for each dilution were determined by fitting ROI intensity values from variable IR images using Igor Pro [18 ]. The longitudinal relaxivity, r_1, was obtained from the slope of 1/T₁ versus (Gd[III]) plots determined from region of interest measurements.

Opina A.C., Wong K.J., Griffiths G.L., Turkbey B.I., Bernardo M., Nakajima T., Kobayashi H., Choyke P.L, & Vasalatiy O. (2014). Preparation and long-term biodistribution studies of a PAMAM dendrimer G5–Gd-BnDOTA conjugate for lymphatic imaging. Nanomedicine (London, England), 10(9), 1423-1437.

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T2WI Imaging of PLGA/GelMA/IKVAV/USPIO Scaffold

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First, the PLGA/GelMA/IKVAV/USPIO composite scaffold was placed in the centrifugal tube, and then all the composite tubular stents were performed T2 weighted imaging (T2WI) in clinical 3T whole body magnetic resonance scanner (SENSE-flex-M; Philips, Best, The Netherlands) using a small extremity coil. The parameters of T2WI were as follows: TR = 5000ms, TE = 5.8 ms, FOV = 8mm × 8mm, matrix size = 64 × 64, in-plane resolution = 125 mm × 125 mm, slice thickness = 0.8 mm.

Xiang Y., Wang W., Gao Y., Zhang J., Zhang J., Bai Z., Zhang S, & Yang Y. (2020). Production and Characterization of an Integrated Multi-Layer 3D Printed PLGA/GelMA Scaffold Aimed for Bile Duct Restoration and Detection. Frontiers in Bioengineering and Biotechnology, 8, 971.

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Quantitative MRI of Cell-Laden Scaffolds

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Nuclear MR imaging was performed in a clinical 3T whole-body MR scanner (PHILIPS Achieva, The Netherlands) using a knee coil (SENSE-flex-M, PHILIPS, The Netherlands) at room temperature. For MR measurements 2 x 10⁶cells were embedded in 0.3 ml gelatin/well (Greiner 96 well Flat Transparent Polystyrol microplate, Germany). T2-weighted images were acquired in 2D scan mode using a multi-slice, multi-shot spin-echo (SE) sequences with a 90° excitation pulse followed by a train of equally spaced 180° refocusing pulses [TR = 1500 ms, TE = 8 - 160 ms, number of echoes = 20, flip angle (FA) = 90°]. For T2* relaxometry, images at 32 echo times [TE range 4 - 94 ms] were acquired by using a multi-shot, multi-slice fast-field gradient-echo (FFE) sequence [TR = 195ms, FA = 30°]. T2 and T2* relaxation times and corresponding R2 and R2* ratios were calculated by fitting an exponential curve to the signal amplitudes as a function of the echo time (TE) for each segmented scaffold region using the Imalytics Preclinical Software (Philips Technologie GmbH, Aachen, Germany). T2- weighted turbo-spin-echo (TSE) sequences were performed using following parameters: TR = 400 ms, TE = 100 ms, FA = 90°.

Mertens M.E., Frese J., Bölükbas D.A., Hrdlicka L., Golombek S., Koch S., Mela P., Jockenhövel S., Kiessling F, & Lammers T. (2014). FMN-Coated Fluorescent USPIO for Cell Labeling and Non-Invasive MR Imaging in Tissue Engineering. Theranostics, 4(10), 1002-1013.

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Multimodal MRI of Monkey Brain

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Monkeys were studied in a 3T clinical MRI (Philips Sense Flex M). Imaging was performed in the axial and coronal plane and included the following sequences: 3D‐time‐of‐flight angiography, T2‐weighted, fluid attenuation inversion recovery (FLAIR), diffusion‐weighted imaging (DWI), and pre‐ and post‐contrast T1‐weighted and perfusion‐weighted imaging (PWI).

Ramsay L., Quillé M., Orset C., de la Grange P., Rousselet E., Férec C., Le Gac G., Génin E, & Timsit S. (2019). Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression. Annals of Clinical and Translational Neurology, 6(9), 1681-1695.

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