Logic p6

Manufactured by GE Healthcare

Sourced in United States

The Logic P6 is a medical imaging device designed for ultrasound examinations. It provides high-quality imaging capabilities to support clinical diagnosis and patient care. The core function of the Logic P6 is to generate and display ultrasound images of the body's internal structures.

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Lab products found in correlation

Hamilton syringe, by Merck Group (1 mentions) Aconitine, by Merck Group (1 mentions) Aplio 500, by GE Healthcare (1 mentions) Aquillion one, by Toshiba (1 mentions) Aquasonic, by Parker Laboratories (1 mentions)

9 protocols using logic p6

SARS-CoV-2 Diagnostic Procedures

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The method used for laboratory confirmation of SARS-CoV-2 infection was throat
swab real-time reverse transcriptase polymerase chain reaction. Blood cell
count, alanine transaminase, aspartate transaminase, renal function, coagulation
profile, C-reactive protein, liver function, D-dimer, troponin, and arterial
blood gases were also determined. All patients underwent chest radiography or
computed tomography. When there was clinical suspicion of DVT, the patient
underwent a full bilateral lower limb venous duplex ultrasound scan (11 MHz
linear transducer, Logic P6, GE Healthcare, Milwaukee, Wisconsin, United
States). In cases of acute arterial occlusion, an additional arterial duplex
ultrasound scan of the affected lower limb was performed to confirm clinical
suspicion.

Correia R.M., Santos B.C., Carvalho A.A., Areias L.L., Kuramoto D.A., Pereda M.R., Aidar A.L., Clezar C.N., Reicher M.E., de Amorim J.E., Flumignan R.L, & Nakano L.C. (2022). Vascular complications in 305 severely ill patients with COVID-19: a cohort study. São Paulo Medical Journal, 141(5), e2022171.

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Aconitine-Induced Ventricular Arrhythmia Protocol

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Aconitine (Sigma Aldrich, St Louis, MO, USA) stock solution (3 µg/mL) was prepared in 50 mL distilled water, and one to two drops of 4 M HCl were added for solubility. Aliquots were stored at −20°C and thawed on ice 3–4 h before injection.^{16 (link)} Aconitine was injected into anterior PM under echocardiographic guidance (Logic P6, GE Healthcare, Tokyo, Japan) by a Hamilton syringe (500 µL, Sigma Aldrich) with a 27 G cannula (Figure 1B and C). Strict care was taken to avoid the contact of Aconitine with the epicardium. Multiple VAs were induced in 12 animals. The median injection dose was 0.06 µg [inter-quartile range (IQR) 0.06–0.15]. Aconitine was given in titrated doses to induce stable monomorphic VA and finally VF.

Münkler P., Klatt N., Scherschel K., Kuklik P., Jungen C., Cavus E., Eickholt C., Christoph J., Lemoine M.D., Christ T., Willems S., Riedel R., Kirchhof P, & Meyer C. (2022). Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle. Europace, 25(2), 688-697.

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Laryngeal Ultrasound and Laryngoscopy

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All patients had laryngeal US done then, followed on the same day by flexible laryngoscopy. The laryngeal US was done using the Toshiba Aplio 500 and General Electric Logic P6 and with a linear probe of (7.5–12 MHz frequency).
Patient preparation No preparation is required. There were no significant risk factors as regards the ultrasound examination in this study (a non-invasive procedure).

Gadalla A.A., Othman K.M., Hamela M.A, & El Bohy A.E. (2022). Value of laryngeal ultrasound in comparison with flexible laryngoscope in diagnosis of various laryngeal masses: a cross-sectional study. The Egyptian Journal of Radiology and Nuclear Medicine, 53(1), 223.

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Radiological Assessment of Renal Abnormalities

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A dedicated radiological review of pertinent computed tomographic (CT) images (Brilliant-16 detectors-Philips, Best, The Netherlands, and Aquillion One-Toshiba, Japan) and ultrasonography (US) studies (Logic P6 and E9, GE Healthcare-Milwaukee-USA) was performed by two dedicated radiologists. All patients had, at least, an abdomen and pelvis CT sequence without intravenous administration of contrast media at hospital admission. If available, sequences after intravenous contrast media were analyzed together. In some cases, CT examinations were performed after the US, and these images were also assessed. The parameters observed were degree of renal dilation (hydronephrosis), presence or absence of urolithiasis, urothelial enhancement, perirenal inflammatory changes (heterogeneous attenuation, fat strandings, and enhancement), and presence of the bear paw sign.

Pais J.S., Rocha M.B., Muglia V.F., Chahud F., Molina C.A., Ruellas H.R, & Tucci S.J. (2022). Xanthogranulomatous pyelonephritis: Case series – Clinical, radiologic, therapeutic, and histological aspects. Urology Annals, 14(4), 383-388.

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Carotid-Femoral Pulse Wave Velocity Measurement

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Carotid–femoral PWV measures were acquired based on previously published guidelines [38 (link)]. Participants were in a fasted state and abstained from alcohol within 24 h of their laboratory visit. Briefly, PWV measures were made via ultrasonography (Logic P6, GE Healthcare, UK, Chalfont Saint Giles) on the right carotid and femoral arteries after a 10 min supine rest. Time was measured from the top of the R wave on the QRS complex to the start of the inflection point on the pulse wave recording on six separate cardiac cycles for both the carotid and femoral artery. The average of these was used as the time measure for the PWV calculation. The actual distance between the carotid and femoral sites was measured in a straight line, and 80% of this measured distance was used in the PWV calculation. This method is demonstrated to be the most accurate means of assessing the distance between the carotid and femoral arteries in humans [38 (link)]. Finally, the difference in the averaged time delay between the carotid and femoral sites was divided by 80%, the measured distance between the sites, to produce the PWV value in meters per second.

Lytle J.R., Stanelle S.T., Martin S.E., Smith S.B., Smith D.R, & Crouse S.F. (2023). Assessment of Vascular Function in Response to High-Fat and Low-Fat Ground Beef Consumption in Men. Nutrients, 15(6), 1410.

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Ultrasonographic Tumor Analysis Using PDI and B Flow

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For ultrasonographic analysis it was used a real-time scanner (Logic P6  , General Electric Healthcare, Milwaukee, WI, USA) and a 10 MHz linear transducer with a standoff pad (Sonokit1, MIUS Ltd, Gloucestershire, England). The animals were placed in supine position and it was applied acoustic gel (Aquasonic  , Parker Laboratories Inc, Fairfield, New Jersey, USA), the ultrasonographic images using Power Doppler (PDI) and B Flow modes were obtained in sagittal planes using light pressure to avoid the distortion of tumors' shape. The images were recorded and the color pixels density (CPD) in PDI and B Flow images was determined according to the formula previously published by Denis et al. [30] , using Adobe Photoshop version 7.0.

Faustino-Rocha A.I., Silva A., Gabriel J., Gil da Costa R.M., Moutinho M., Oliveira P.A., Gama A., Ferreira R, & Ginja M. (2016). Long-term exercise training as a modulator of mammary cancer vascularization. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 81.

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Mesenteric Artery Doppler Changes Post Blood Transfusion

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The Doppler measurements were performed using an ultrasound scanner with a 7 MHz probe (Logic P6, GE Healthcare, US). The superior mesenteric artery (SMA) peak systolic and diastolic velocities were measured 30-60 minutes before and after blood transfusion using a range-gated pulsed wave Doppler ultrasound scan (Figure 1). The Doppler measurements were performed by a single operator (JB) to minimise intra-operator variability and utmost care was taken to minimise the angle of insonation to the direction of flow. When this was more than 30° angle correction was performed. The probe was placed in the infra-diaphragmatic region (longitudinal view) to measure SMA blood flow 20 . Cardiac morphology and presence of patent ductus arteriosus (PDA) was also recorded.

Banerjee J., Leung T.S, & Aladangady N. (2016). Effect of blood transfusion on intestinal blood flow and oxygenation in extremely preterm infants during first week of life. Transfusion, 56(4).

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Cerebral Blood Flow Changes After Transfusion

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The Doppler measurements were performed using an ultrasound scanner with a 7 MHz probe (Logic P6, GE Healthcare, US). The anterior cerebral artery (ACA) peak systolic and time averaged mean velocities (TAMV) as well as pulsatility and resistance indices were measured 30-60 minutes pre and post blood transfusion using a range-gated pulsed wave Doppler ultrasound scan placing the probe over the anterior fontanel in parasagittal view.
Superior vena cava (SVC) flow was measured using the classical method by placing the probe in the infra-diaphragmatic view to measure the velocity time integral (VTI) and then again over the true long axis to measure the diameter of the SVC pre and post blood transfusion. The Doppler measurements were performed by single operator (JB) to minimise intra-operator variability and utmost care was taken to minimise the angle of insonation to the direction of flow. When this was more than 30° angle correction was performed. Cardiac morphology and presence of patent ductus arteriosus (PDA) was also recorded.

Banerjee J., Leung T.S, & Aladangady N. (2016). Cerebral blood flow and oximetry response to blood transfusion in relation to chronological age in preterm infants. Early human development, 97.

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Mesenteric Artery Doppler in Transfusion

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The superior mesenteric artery (SMA) peak systolic and diastolic velocities were measured 30-60 minutes before and after blood transfusion using a 7 MHz Doppler probe with rangegated pulsed wave Doppler ultrasound scanner (Logic P6, GE Healthcare, US). The measurements were performed by a single operator (JB) to minimise intra-operator variability (intra-class correlation coefficient for SMA PSV 0.77, p=0.02 and mean difference 0.02). A mean of five cardiac cycles was taken for Doppler measurements.

Banerjee J., Leung T.S, & Aladangady N. (2016). Blood transfusion in preterm infants improves intestinal tissue oxygenation without alteration in blood flow. Vox sanguinis, 111(4).

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