Ceramide peg n palmitoyl sphingosine 1 succinyl methoxy polyethylene glycol

Manufactured by Avanti Polar Lipids

Ceramide-PEG (N-palmitoyl-sphingosine-1-(succinyl{methoxy[polyethylene glycol]})) is a synthetic lipid compound. It consists of a ceramide moiety linked to a polyethylene glycol (PEG) group. The core function of this product is to serve as a versatile building block for the development of lipid-based delivery systems and formulations.

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Lab products found in correlation

Magnesium sulfate, by Merck Group (2 mentions) Egfp mrna, by TriLink (2 mentions) Ova mrna, by TriLink (2 mentions) Cationic ethylenediamine core poly amidoamine pamam generation 0 dendrimer, by Merck Group (2 mentions) Palmitic acid c16 cooh resiquimod r848 anhydrous dichloromethane dcm n n dicyclohexylcarbodiimide dcc, by Merck Group (2 mentions) Anhydrous n n dimethylformamide dmf 4 dimethylaminopyridine dmap hydrochloric acid hcl, by Merck Group (2 mentions) Lipofectamine 2000 l2k, by Thermo Fisher Scientific (2 mentions)

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Ceramides (7 citations)

2 protocols using ceramide peg n palmitoyl sphingosine 1 succinyl methoxy polyethylene glycol

Lipid-Dendrimer Nanocarriers for mRNA Delivery

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EGFP mRNA and OVA mRNA (each modified with pseudouridine and 5-methylcytidine) were purchased from TriLink Biotechnologies. Cationic ethylenediamine core-poly(amidoamine) (PAMAM) generation 0 (G0) dendrimer, palmitic acid (C16–COOH), resiquimod (R848), anhydrous dichloromethane (DCM), N,N′-dicyclohexylcarbodiimide (DCC), anhydrous N,N-dimethylformamide (DMF), 4-dimethylaminopyridine (DMAP), hydrochloric acid (HCl), and magnesium sulfate were purchased from Sigma-Aldrich. Ceramide-PEG (N-palmitoyl-sphingosine-1-(succinyl{methoxy[polyethylene glycol]}) with PEG MW of 2000 was obtained from Avanti Polar Lipids. Lipofectamine 2000 (L2K) was purchased from Invitrogen.

Islam M.A., Rice J., Reesor E., Zope H., Tao W., Lim M., Ding J., Chen Y., Aduluso D., Zetter B.R., Farokhzad O.C, & Shi J. (2020). Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice. Biomaterials, 266, 120431.

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Lipid-Polymer Hybrid Nanoparticles for mRNA Delivery

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EGFP mRNA and OVA mRNA (each modified with pseudouridine and 5-methylcytidine) were purchased from TriLink Biotechnologies. Cationic ethylenediamine core-poly(amidoamine) (PAMAM) generation 0 (G0) dendrimer, palmitic acid (C16-COOH), resiquimod (R848), anhydrous dichloromethane (DCM), N,N’-dicyclohexylcarbodiimide (DCC), anhydrous N,N-dimethylformamide (DMF), 4-dimethylaminopyridine (DMAP), hydrochloric acid (HCl), and magnesium sulfate were purchased from Sigma-Aldrich. Ceramide-PEG (N-palmitoyl-sphingosine-1-(succinyl{methoxy[polyethylene glycol]}) with PEG MW of 2000 was obtained from Avanti Polar Lipids. Lipofectamine 2000 (L2K) was purchased from Invitrogen.

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