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Prism version 8 for mac

Manufactured by GraphPad
Sourced in United States

Prism version 8 for Mac is a data analysis and graphing software designed for scientific applications. It offers tools for data visualization, curve fitting, and statistical analysis. The software is optimized for use on Mac operating systems.

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3 protocols using prism version 8 for mac

1

Survival Analysis of Experimental Treatments

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In this study, statistical analyses were performed using Prism version 8 for Mac (GraphPad Software, San Diego) and SPSS 19.0 for Mac (IBM SPSS Statistics, Chicago). Each group’s survival time was plotted as a Kaplan-Meier survival curve, and the groups’ survival times were compared using the log-rank test. The effects of several variables on survival time were investigated using Cox proportional hazards regression analysis. Serum albumin levels were compared using Student’s t-test. The significance level was determined as a p-value < 0.05.
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2

Toxicity Analysis of Au-PEI and Au-PEG Nanoparticles

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LC50 [median lethal concentration] and EC50 [median effective (teratogenic) concentration] were calculated using Prism version 8 for Mac (GraphPad LLC, San Diego, CA, USA) and performing nonlinear regression (curve fit) analysis with the equation for the four-parameter logistic curve (Sigmoidal 4PL). Curve charts for LC50 and EC50 with Au-PEI25kB and PEI25kB were obtained from the sigmoidal 4PL analysis.
The survival and malformation rates from multiple comparisons among various concentrations of Au-PEI25kB were evaluated using a one-way analysis of variance (ANOVA; nonparametric Kruskal-Wallis test) using the same software. The survival and malformation rates between the Au-PEG5k-OMe treatment and the control groups did not show significant differences using the Kolmogorov-Smirnov test. The Chi-square test was used to evaluate malformation features relative to the control using the Prism 8 software. For TEM data analysis, arbitrary values for the linear or spatial AuNP counts were evaluated using the nonparametric t-test (Kolmogorov-Smirnov D test) to compare the Au-PEI25kB and Au-PEG5k-OMe data sets using Prism 8.
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3

Evaluating Nanoparticle Cytotoxicity and Malformation

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LC50 [median lethal concentration] and EC50 [median effective (teratogenic) concentration] were calculated using Prism version 8 for Mac (GraphPad LLC, San Diego, CA, USA) and performing nonlinear regression (curve fit) analysis with the equation for the four-parameter logistic curve (Sigmoidal 4PL). Curve charts for LC50 and EC50 with Au-PEI25kB and PEI25kB were obtained from the sigmoidal 4PL analysis.
The survival and malformation rates from multiple comparisons among various concentrations of Au-PEI25kB were evaluated using a one-way analysis of variance (ANOVA; nonparametric Kruskal-Wallis test) using the same software. The survival and malformation rates between the Au-PEG5k-OMe treatment and the control groups did not show significant differences using the Kolmogorov-Smirnov test. The Chi-square test was used to evaluate malformation features relative to the control using the Prism 8 software. For TEM data analysis, arbitrary values for the linear or spatial AuNP counts were evaluated using the nonparametric t-test (Kolmogorov-Smirnov D test) to compare the Au-PEI25kB and Au-PEG5k-OMe data sets using Prism 8.
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