Rstudio under r4

The prospective multicentre observational study CIRT (NCT02305459) was conducted by the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) to evaluate the real-world clinical application and outcomes of TARE with Y90 resin microspheres (SIR-Spheres® Y-90 resin microspheres, Sirtex Medical Pty Limited; St. Leonards, NSW, Australia). Sites were invited to participate if they performed at least 40 TARE cases in total and ten cases in the twelve months prior to invitation. The 27 participating sites were identified and enrolled between April 2014 and April 2017.
The CIRT methodology was previously published [17 (link)]. Data were collected using a customised electronic data capturing system and electronic case report form that was developed by ConexSys Inc (Lincoln, RI, USA) and hosted on a local secure server in Vienna, Austria, maintained by ITEA (Vienna, Austria). Statistical analyses were performed in SAS 9.4 (SAS Institute, Cary, NC, USA) and RStudio under R4.0.0 (R Foundation, Vienna, Austria).

We analysed 422 patients with HCC collected in the CIRSE Registry for SIR-Spheres Therapy (CIRT) study. CIRT is a prospective, single device, multi-centre observational study of patients with primary and metastatic hepatic malignancies treated with TARE using Y90 resin microspheres as the standard of care. The CIRT methodology was published by Helmberger et al.²⁶ Sites were invited to participate if they had at least 40 TARE cases and 10 cases in 12 months prior to invitation. In total, 27 participating sites in eight countries were identified and enrolled from April 2014 until April 2017, of which 25 sites included patients with HCC.²⁵ (link)
Data was collected using a customised electronic data capturing system and electronic case report form that was developed by ConexSys Inc (Lincoln, RI, United States) and hosted on a local secure server in Vienna, Austria maintained by ITEA (Vienna, Austria). Statistical analyses were performed in SAS 9.4 (SAS Institute, Cary, NC, USA) and RStudio under R4.0.0 (R Foundation, Vienna, Austria, Supplementary CTAT Table).