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Ge encore

Manufactured by GE Healthcare
Sourced in United States

The GE Encore is a versatile laboratory equipment designed for various analytical and research applications. It functions as a high-performance imaging system, capable of capturing detailed images and data for scientific analysis. The core purpose of the GE Encore is to provide researchers and scientists with a reliable and efficient tool for their laboratory work.

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4 protocols using ge encore

1

Comprehensive Body Composition Assessment

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Body mass was measured to the nearest 0.1 kg using a digital weighing scale (Scotland: Soehnle Connect, Soehnle-Waagen GmbH and Co.KG, Murrhardt, Germany; South Africa: BW-150, NAGATA, Tainan, Taiwan) in light-weight clothing without shoes, and height was assessed to the nearest 0.1 cm using a portable stadiometer (Scotland: Seca 213, Birmingham, UK; South Africa: 3PHTROD-WM, Detecto, MO, USA). Body mass index (BMI) was computed as body mass (kg)/height (m2) and classified according to World Health Organization (WHO) criteria [32 ].
Whole and subtotal (whole-body minus head) body composition, including fat-free soft tissue mass (FFSTM), fat mass, and BMD were measured using dual energy X-ray absorptiometry (Scotland: iDXA; GE Encore, version 13.40.038, GE Healthcare, Madison, WI, USA; South Africa: DXA; Discovery-W®, version 12.7.3.7, Hologic, Bedford, MA, USA) according to standard procedures. Appendicular skeletal muscle mass (ASM), the sum of FFSTM (kg) of both legs and arms, was adjusted for BMI (ASMBMI). BMD was quantified using DXA at the lumbar spine (lumbar vertebrae L1-L4), total hip, and femoral neck.
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2

Bone Density Assessment in Participants

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The main outcome of this study was the presence of osteopenia and osteoporosis assessed from BMD, obtained using DXA (GE Lunar Prodigy Advance®, GE Healthcare, Chicago, IL, USA), duly calibrated, and using the GE Encore® software, version 14.10, configured to use the National Health and Nutrition Examination Survey [21 ]. The BMD of the femoral neck and lumbar spine (L3 and L4 positions) was evaluated. All densitometry tests were performed by a trained radiology technician and the result reported by a single specialist physician to avoid interobserver variation. Data were extracted from medical records, and the results of exams performed up to six months before or after the study were included. Participants were classified into three groups: (1) Normal BMD (T-score ≥ −1.0 SD), (2) Osteopenia (T-score between −1.0 and −2.5 SD), and (3) Osteoporosis (T-score ≤ −2.5 SD) [22 ].
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3

Measuring Blood Pressure and Body Composition

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Diastolic and systolic blood pressure (BP) were measured to the nearest 2 mmHg in the supine position after 5 min rest, using a standard mercury sphygmomanometer with appropriately sized cuff. The average of three measurements on different days was used.
Dual energy X-ray absorptiometry (DXA) was used for measurements of fat mass in kg (FM), fat mass percentage (FM%), fat-free mass in kg (FFM) and fat-free mass percentage (FFM%), using a GE-Lunar Prodigy scanner with GE Encore software version 8.80 (GE Medical Systems, Milwaukee, WI, USA) [17 (link)]. No sedation was required. All scans were performed and analyzed by the same operator.
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4

DXA Scanning Procedure for Body Composition

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All DXA scans were undertaken in the whole body mode on a pencil beam DXA scanner (Lunar DPX; GE Healthcare) with analysis performed using GE enCORE version 13.60 software (GE Healthcare) with the combined Geelong/Lunar reference database. CV for the laboratory being 0•1, 2•2, 0•6 and 1•0 % for BM, FM, lean mass and BMC respectively. The DXA was calibrated with phantoms as per the manufacturer's guidelines each day before measurements were taken. All scans were conducted by the same Queensland Radiation Health licensed technician using the standard thickness mode as determined by the auto scan feature in the software and all safety protocols as per the Institution's Radiation Safety Protection Plan were adhered to.
The scans were performed according to a protocol developed that emphasises a consistent positioning of subjects on the DXA scanning bed (10) as previously described (18) . In addition, two Velcro straps were used to minimise any subject movement during the scan as well as provide a consistent body position for subsequent scans. One strap was secured around the ankles above the foot positioning pad and the other strap was secured around the trunk at the level of the mid forearms (19) . All scans were analysed automatically by the DXA software but all regions of interest were reconfirmed before being included in the subsequent statistical analysis.
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