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Tanshinone 1

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Tanshinone I is a natural product isolated from the root of Salvia miltiorrhiza, commonly known as Danshen. It is a non-pharmacological laboratory reagent used for research purposes.

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Lab products found in correlation

Crystal violet staining solution, by Beyotime (1 mentions) Ferrostatin 1, by Selleck Chemicals (1 mentions) C11 bodipy581 591, by Thermo Fisher Scientific (1 mentions) Trolox, by MedChemExpress (1 mentions) Cisplatin, by MedChemExpress (1 mentions) Sulfasalazine, by MedChemExpress (1 mentions) Cryptotanshinone, by MedChemExpress (1 mentions) Tanshinone iia, by MedChemExpress (1 mentions) Erastin, by MedChemExpress (1 mentions)

2 protocols using tanshinone 1

1

Tanshinone I and Ferrostatin-1 Stock Preparation

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Tanshinone I (MedChemExpress, Cat#HY-N0134) and Ferrostatin-1 (Selleck, Cat# S7243) were dissolved in dimethyl sulfoxide (DMSO) at 10 mM stock concentration and stored in aliquots at −20 °C. Thiazolyl blue tetrazolium bromide (MTT, Sigma, Cat#M2128) was dissolved in phosphate-buffered saline (PBS) at 5 mg/mL concentration and stored in aliquots at 4 °C. Crystal violet staining solution (Cat#C0121) was purchased from Beyotime Biotechnology.
Zhang M., Xiang R., Glorieux C, & Huang P. (2022). PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation. International Journal of Molecular Sciences, 23(19), 11721.
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2

Investigating Lipid Peroxidation Inhibitors

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Cryptotanshinone, tanshinone I, tanshinone IIA, erastin, RSL3, sulfasalazine, Trolox, and cisplatin were purchased commercially from MedChemExpress (MCE). NADH and H2O2 were purchased from Beyotime Biotechnology. L-α-phosphatidylcholine (egg, chicken) was purchased from Merck. AAPH was purchased from Sigma-Aldrich. C11-BODIPY581/591 was purchased from Invitrogen.
Wang T.X., Duan K.L., Huang Z.X., Xue Z.A., Liang J.Y., Dang Y., Zhang A., Xiong Y., Ding C., Guan K.L, & Yuan H.X. (2022). Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis. Life Science Alliance, 6(1), e202201667.
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