Pnu 282987

Manufactured by Pfizer

Sourced in United States, United Kingdom

PNU-282987 is a lab equipment product developed by Pfizer. It is a highly sensitive and precise instrument used for the detection and analysis of various biological and chemical compounds. The core function of PNU-282987 is to provide accurate and reliable measurements, enabling researchers to gather critical data for their scientific investigations.

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Lab products found in correlation

Pnu 120596, by Pfizer (2 mentions) Donepezil, by Abcam (1 mentions) Methyllycaconitine mla, by Abcam (1 mentions) Mecamylamine hydrochloride, by Merck Group (1 mentions) Methyllycaconitine citrate, by Bio-Techne (1 mentions) Nicotine hydrogen tartrate, by Merck Group (1 mentions) Pluronic f 127, by Thermo Fisher Scientific (1 mentions) Tetrodotoxin citrate, by Bio-Techne (1 mentions) Sazetidine a dihydrochloride, by Bio-Techne (1 mentions) Fluo 3 am, by Thermo Fisher Scientific (1 mentions) Fura 2 am, by Thermo Fisher Scientific (1 mentions) L glutamine, by Thermo Fisher Scientific (1 mentions) Triton x 100, by Merck Group (1 mentions)

2 protocols using pnu 282987

Pharmacological Modulation of Neuronal Receptors

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Methyllycaconitine (MLA), donepezil, TTX and 6,7-dinitroquinoxaline-2,3-dione (DNQX) were purchased from Abcam. PNU-120596 and PNU-282987 were provided by Pfizer Inc. USA. All other drugs and compounds were purchased from Sigma Aldrich.

Udakis M., Wright V.L., Wonnacott S, & Bailey C.P. (2016). Integration of inhibitory and excitatory effects of α7 nicotinic acetylcholine receptor activation in the prelimbic cortex regulates network activity and plasticity. Neuropharmacology, 105, 618-629.

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Neuronal Calcium Signaling Assay

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Triton X-100, (-)-nicotine hydrogen tartrate and mecamylamine hydrochloride, were purchased from Sigma-Aldrich (Poole, Dorset, UK); B27, l-glutamine, antibiotics, fluo-3 AM, fura-2 AM, and pluronic f127 were obtained from Life Technologies (Paisley, UK); sazetidine-A dihydrochloride, tetrodotoxin citrate, methyllycaconitine citrate and 5-iodo-A85380 dihydrochloride were purchased from Tocris Bioscience (Avonmouth, UK); PNU-120596 and PNU-282987 were provided by Pfizer Inc. USA; general reagents were purchased from Fisher Scientific (Loughborough, UK).

Brown J.L, & Wonnacott S. (2014). Sazetidine-A Activates and Desensitizes Native α7 Nicotinic Acetylcholine Receptors. Neurochemical Research, 40(10), 2047-2054.

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