Zantac

As mentioned above, when all pH measurements were ceased, any required analgesic intervention was instituted to ensure adequate post-operative pain relief. Rescue analgesia with morphine 0.2 mg/kg IM and fentanyl 2 μg/kg IV to effect were administered during recovery as required.
All cases with documented GOR during anesthesia underwent esophageal lavage with NaCl 0.9% (normal saline) at the end of the surgery and received prophylactic treatment for esophagitis. The treatment included metoclopramide (Primperan; Sanofi-Aventis, Kallithea, Greece) at 0.2 mg/kg BID (twice a day) per os, ranitidine (Zantac; GlaxoSmithKline, Chalandri, Greece) at 2 mg/kg BID per os and sucralfate (Peptonorm; Uni-Pharma, Kifisia, Greece) at 30 mg/kg BID per os. Treatment was instituted for 5 days and the owners were encouraged to inform the clinic if they observed any signs of vomiting, hypersalivation, or regurgitation that persisted.

A seven-day treatment with ranitidine (Zantac; GlaxoSmithKline Hellas, Athens, Greece, 2 mg/kg BW, PO, BID), metoclopramide (Primperan; Sanofi-aventis Hellas, Athens, Greece, 0.3 mg/kg BW, PO, BID) and sucralfate (Peptonorm; Uni-Pharma, Athens, Greece, 30 mg/kg BW, QID, PO) was recommended for all the dogs that experienced GOR. The owners of these animals were informed about the possible complications, such as oesophagitis and oesophageal stricture, and were instructed to contact the clinic if their dogs showed any sign of oesophageal dysfunction, such as unexplained anorexia, regurgitation, vomiting or hypersalivation.