100 series spectrophotometer fourier transform infrared ftir

Shimadzu XRD-6000 Diffractometer (Shimadzu Corporation, Tokyo, Japan) was used for X-ray diffraction (XRD) studies with CuKα radiation at 30 kV and 30 mA. A Perkin-Elmer 100 series spectrophotometer Fourier transform infrared (FTIR) (Waltham, MA, USA) was applied for the functional group analysis and spectra were recorded by the direct sample method. For the optical and in vitro release studies a Perkin Elmer Lambda 35 ultraviolet-visible spectrophotometer (Waltham, MA, USA) was used. The Raman spectra were recorded with excitation wavelength (598 nm) using Raman spectrometer Witec Model: Alpha 300R (Witec, Ulm, Germany). The drug loading was quantified using Sykam high performance liquid chromatography (HPLC) system (SYKAM GmbH, Eresing, Germany) was used with the a Sykam S3250 UV/Vis detector auto injector Sykam 5300, and the Sykam quaternary pump system 5300 made in Germany, with a Zorbax Rx-Sil column of 4.6 × 150 mm, with 5 μm particle size (Agilent Technologies, Santa Clara, CA, USA).

For X-ray diffraction (XRD) studies, a Shimadzu XRD-6000 Diffractometer (Shimadzu Corporation, Tokyo, Japan), was utilized with CuK_α radiation at 30 kV and 30 mA. For the functional group analysis, a Perkin-Elmer (Waltham, MA, USA) 100 series spectrophotometer Fourier Transform infrared (FTIR) was used, and spectra were recorded by the direct sample method. For the optical and release studies, a Lambda 35 ultraviolet-visible spectrophotometer (Perkin Elmer) was used. A Raman spectrometer, Witec Model: Alpha 300R was used for the RAMAN analysis of the samples with 532 nm excitation. For drug quantification, Sykam high performance liquid chromatography (HPLC) system (SYKAM GmbH, Eresing, Germany) was used with the auto injector Sykam 5300, a Sykam S3250 UV/Vis detector, and the Sykam quaternary pump system 5300 made in Germany, with a Zorbax Rx-Sil column of 4.6 × 150 mm, and with 5 μm particle size (Agilent Technologies, Santa Clara, CA, USA).