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Rabbit anti hif 1α monoclonal antibody

Manufactured by Merck Group
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Rabbit-anti-HIF-1α monoclonal antibody is a laboratory reagent designed for the detection and analysis of the hypoxia-inducible factor-1 alpha (HIF-1α) protein. This antibody is specific to the HIF-1α subunit and can be used in various immunological techniques to study the expression and regulation of this transcription factor, which plays a crucial role in the cellular response to low oxygen conditions.

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Lab products found in correlation

Rabbit anti vegf monoclonal antibody, by Merck Group (3 mentions) Rabbit anti gapdh monoclonal antibody, by Merck Group (3 mentions) Diazoxide, by Merck Group (2 mentions) Ros scavenger n 2 mercaptopropionylglycine, by Merck Group (2 mentions) Hif 1 agonist dimethyloxaloylglycine, by Merck Group (2 mentions)

3 protocols using rabbit anti hif 1α monoclonal antibody

1

Cardioprotective Preconditioning Mechanisms

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Diazoxide, mitoKATP blocker −5-hydroxydecanoate (5-HD), ROS scavenger—N-2-mercaptopropionylglycine (MPG), and HIF-1 agonist—dimethyloxaloylglycine (DMOG) were purchased from Sigma (St. Louis, MO, USA). Rabbit-anti-HIF-1α monoclonal antibody, rabbit-anti VEGF monoclonal antibody, and rabbit-anti-GAPDH monoclonal antibody were purchased from Sigma. Pentobarbital was purchased from Shanghai Tyrael Biological Technology Co., Ltd. The study was approved by the Institutional Review Board of The Affiliated Hospital of Zunyi Medical University, Guizhou, China.
Chen X.Y., Wang J.Q., Cheng S.J., Wang Y., Deng M.Y., Yu T., Wang H.Y, & Zhou W.J. (2021). Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes. Frontiers in Cardiovascular Medicine, 8, 711465.
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2

Investigating Hypoxia Signaling Pathways

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Sevoflurane was purchased from Maruishi Pharmaceutical, Japan. Rabbit-anti-HIF-1α monoclonal antibody, rabbit-anti-VEGF monoclonal antibody, rabbit-anti-eNOS monoclonal antibody, and rabbit-anti-GAPDH monoclonal antibody were purchased from Sigma, USA. HIF-1α inhibitor 2ME2 was purchased from selleck, USA. Pentobarbital was purchased from Shanghai Tyrael Biological Technology Co., LTD.
Wu J., Yang L., Xie P., Yu J., Yu T., Wang H., Maimaitili Y., Wang J., Ma H., Yang Y, & Zheng H. (2017). Cobalt Chloride Upregulates Impaired HIF-1α Expression to Restore Sevoflurane Post-conditioning-Dependent Myocardial Protection in Diabetic Rats. Frontiers in Physiology, 8, 395.
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3

Cardioprotective Preconditioning Mechanisms

Check if the same lab product or an alternative is used in the 5 most similar protocols
Diazoxide, mitoKATP blocker −5-hydroxydecanoate (5-HD), ROS scavenger—N-2-mercaptopropionylglycine (MPG), and HIF-1 agonist—dimethyloxaloylglycine (DMOG) were purchased from Sigma (St. Louis, MO, USA). Rabbit-anti-HIF-1α monoclonal antibody, rabbit-anti VEGF monoclonal antibody, and rabbit-anti-GAPDH monoclonal antibody were purchased from Sigma. Pentobarbital was purchased from Shanghai Tyrael Biological Technology Co., Ltd. The study was approved by the Institutional Review Board of The Affiliated Hospital of Zunyi Medical University, Guizhou, China.
Chen X.Y., Wang J.Q., Cheng S.J., Wang Y., Deng M.Y., Yu T., Wang H.Y, & Zhou W.J. (2021). Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes. Frontiers in Cardiovascular Medicine, 8, 711465.
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