Compound 101 hb2840

Manufactured by Hello Bio

Sourced in United Kingdom

Compound 101 (HB2840) is a laboratory reagent manufactured by Hello Bio. It is a chemical compound used in various research applications. The core function of Compound 101 is to serve as a research tool, providing researchers with a standardized and reliable substance for their experiments.

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Compound 101 (2 citations)

2 protocols using compound 101 hb2840

Opioid Receptor Ligand Procurement

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SNC80 (ab120684) was obtained from Abcam (Cambridge, UK). DADLE (E7131), fentanyl (F3886), [Met]-enkephalin (M6638), morphin-6-glucuronide (M3528), naloxone (N7758), deltorphin II (T0675), [Leu]-enkephalin (L91333) and phorbol-12-myristat-13-acetat (PMA) (P8139) were purchased from Sigma-Aldrich (Steinheim, Germany). DPDPE (1431), naltrindole (0740), naltribene (0892), naltrexone (0677), AR-M1000390 (4335) and forskolin (1099) were obtained from Tocris (Wiesbaden-Nordenstadt, Germany). Norbuprenorphine (BUP-982-FB) and buprenorphine (BUP-399-HC) were purchased from Lipomed (Arlesheim, Switzerland). ADL5859 (Axon1751) was obtained from Axonmedchem (Groningen, Netherlands). Levomethadone (00424906) was purchased from Sanofi-Aventis (Frankfurt, Germany). Morphine (26-6) was obtained from Merck Pharma (Darmstadt, Germany). Lambda-phosphatase (P0753S) and deltorphin I (sc-396073) were purchased from Santa Cruz (Heidelberg, Germany). Compound 101 (HB2840) was obtained from Hello Bio (Bristol, UK).

Mann A., Liebetrau S., Klima M., Dasgupta P., Massotte D, & Schulz S. (2020). Agonist-induced phosphorylation bar code and differential post-activation signaling of the delta opioid receptor revealed by phosphosite-specific antibodies. Scientific Reports, 10, 8585.

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Dopaminergic Receptor Ligand Assays

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Terguride (ab144611) was obtained from Abcam. Aripiprazole (SML-0935), PMA (P8139) and pergolide mesylate (P8828) were purchased from Sigma-Aldrich. Apomorphine hydrochloride (2073), MLS1547 (6171), ropinirole (3680), quinpirole hydrochloride (1061), dopamine hydrochloride (3548), cabergoline (2664), bromocriptine mesylate (0427), forskolin (1099), SCH23390 (0925), PTX (3097), haloperidol hydrochloride (0931), L-741,626 (1003) and roxindole (1559) were obtained from Tocris. UNC9994 (A16087) was purchased from AdooQ Bioscience. Lambda-phosphatase (P0753S) was obtained from Santa Cruz. Compound 101 (HB2840) was obtained from Hello Bio. Terguride, PMA, forskolin, L-741,626, aripiprazole, pergolide, apomorphine, MLS1547, ropinirole, cabergoline, bromocriptine, haloperidol, roxindole, UNC9994 and compound 101 are DMSO-soluble and all the other mentioned compounds are water-soluble.

Mann A., Keen A.C., Mark H., Dasgupta P., Javitch J.A., Canals M., Schulz S, & Robert Lane J. (2021). New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling. Scientific Reports, 11, 8288.

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