Anti madcam1 meca367

Manufactured by BioXCell

The Anti-MADCAM1 (MECA367) is a monoclonal antibody that binds to the MAdCAM-1 (mucosal addressin cell adhesion molecule-1) protein. MAdCAM-1 is involved in the recruitment and homing of lymphocytes to mucosal tissues. This antibody can be used in research applications to study the role of MAdCAM-1 in biological processes.

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Lab products found in correlation

Anti igd 11 26c 2a, by BioLegend (1 mentions) Anti vcam1 429, by BD (1 mentions) Anti cd35 8c12, by BD (1 mentions) Rat igg2a isotype control 2a3, by BioXCell (1 mentions) Anti cd11a m17 4, by BioXCell (1 mentions)

2 protocols using anti madcam1 meca367

Immunohistochemical Staining of Cryosections

Cited 1 time

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Cryosections 7um in thickness were cut and fixed in cold acetone.
Sections were stained with anit-ICAM1 (3E2; BD Biosciences); anti-VCAM1 (429; BD
Biosciences); anti-MADCAM1(MECA367; Bio X Cell); anti-IgD (11-26c.2a;
Biolegend); anti-Vitronectin (347317; R&D); rat IgG2a isotype control
(2A3; Bio X Cell) or anti-CD35 (8C12; BD Biosciences) using described protocols
(36 (link)).

Wang X., Rodda L., Bannard O, & Cyster J.G. (2014). Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness. Journal of immunology (Baltimore, Md. : 1950), 192(10), 4601-4609.

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Blocking Effectors and HR Ligands in Tumor Models

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Effectors were blocked with either 100 μg anti-rat IgG (Jackson Immunoresearch), anti-α₄ (PS/2) (ATCC), anti-CD44 (IM7), anti-α₄β₇ (DATK32) or anti-CD11a (M17/4) (all BioXcell) for 30 min before injection into tumor-bearing animals. HR ligands were blocked by IP injection of 100 μg anti-VCAM-1 (M/K-2.7) or anti-MadCAM-1 (MECA-367) (BioXcell) 6h prior to effector transfer.

Woods A.N., Wilson A.L., Srivinisan N., Zeng J., Dutta A.B., Peske J.D., Tewalt E.F., Gregg R.K., Ferguson A.R, & Engelhard V.H. (2017). Differential expression of homing receptor ligands on tumor associated vasculature that control CD8 effector T cell entry. Cancer immunology research, 5(12), 1062-1073.

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