1.5t clinical mri systems

MRI-examinations were performed to determine liver fat content (LFC) and volumes of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) as previously described (23 (link)). All exams were performed using 1.5T clinical MRI-systems from Philips Medical System (Amsterdam, The Netherlands) after a light meal and in close proximity to the OGTT. Water-fat imaging techniques were used throughout. The scans were done over 16 cm along the craniocaudal axis and centered on the L1 vertebra. The adipose tissue volumes were determined using a fully automated segmentation method that uses a filtering technique to separate VAT from SAT. Liver fat image reconstruction was done by a multi-resolution version of a method that employs a whole-image optimization approach (27 (link)). A single operator trained by an experienced radiologist performed the measurements by manual segmentation in the axial slices of the water images using the software ImageJ (version 1.42q, http://rsbweb.nih.gov/ij/).

MRI-examinations were performed to determine liver fat content (LFC) and volumes of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) as previously described (29 (link)). All exams were performed using 1.5 T clinical MRI-systems from Philips Medical System (Netherlands) after a light meal and in close proximity to the OGTT. Water-fat imaging techniques were used throughout. The scans were done over 16 cm along the craniocaudal axis and centered on the L1 vertebra. The adipose tissue volumes were determined using a fully automated segmentation method that uses a filtering technique to separate VAT from SAT. Liver fat image reconstruction was done by a multi-resolution version of a method that employs a whole-image optimization approach (30 (link)). A single operator trained by an experienced radiologist performed the measurements by manual segmentation in the axial slices of the water images using the software ImageJ (version 1.42q, http://rsbweb.nih.gov/ij/).