Cs 2500 automated coagulation analyzer

Manufactured by Sysmex

Sourced in Japan

The CS 2500 is an automated coagulation analyzer designed for clinical laboratories. It is capable of performing a range of coagulation tests, including prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen analysis. The CS 2500 automates the testing process, providing efficient and reliable results.

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Lab products found in correlation

Unicel dxh 800 hematology analyzer, by Beckman Coulter (2 mentions) Au5800 chemistry analyzer, by Beckman Coulter (2 mentions) Advia centaur xp immunoassay analyzer, by Siemens (1 mentions)

Close spelling variants of this product

Sysmex CS‐2500 coagulation analyzer CS-2500 Sysmex automated analyzer

3 protocols using cs 2500 automated coagulation analyzer

COVID-19 Diagnostic Laboratory Protocol

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Patients’ demographic data, signs and symptoms, comorbidities, and laboratory data were reviewed and collected from the hospital’s electronic information system. Laboratory data of the patients within the first 24 h after admission to the hospital were evaluated.
Complete blood count analyses were performed in UniCel DxH 800 hematology analyzer (Beckman Coulter, Miami, FL, USA), while C-reactive protein (CRP), glucose, creatinine, alanine aminotransferase (ALT), aspartate aminotransferase (AST), direct bilirubin (DBil), total bilirubin (TBil), and ferritin analyses were performed in AU 5800 chemistry analyzer (Beckman Coulter, High Wycombe, UK). ADVIA Centaur XP immunoassay analyzer (Siemens Healthineers, Erlangen, Germany) was used for high sensitive troponin I (hs-TNI) analyses. CS 2500 automated coagulation analyzer (Sysmex Corporation, Kobe, Japan) was used for prothrombin time (PT) and activated partial prothrombin time (APTT) determination. COVID-19 diagnosis was done by real-time polymerase chain reaction (RT-PCR) (Bio-Speedy COVID-19 RT-qPCR kit, Bioeksen R&D Technologies Ltd, Istanbul, Turkey) of viral nucleic acids form throat swab samples.

Karakoyun I., Colak A., Turken M., Altin Z., Arslan F.D., Iyilikci V., Yilmaz N, & Kose S. (2020). Diagnostic utility of C-reactive protein to albumin ratio as an early warning sign in hospitalized severe COVID-19 patients. International Immunopharmacology, 91, 107285.

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Comprehensive Laboratory Profiling in COVID-19

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Patient demographic characteristics, including age, sex, vaccination rate, and underlying diseases, were obtained from the hospital’s electronic information system. Laboratory parameters were evaluated within 24 hours of admission.
Complete blood count analyses (including total and differential leukocyte counts) were performed using a BC7500 Automated Hematology Analyzer (Mindray Corp., Shenzhen, China). CRP and serum amyloid A (SAA) levels were measured using an Aristo-Specific Protein Analyzer (Goldsite Diagnostics, Shenzhen, China). Total protein (TP), albumin, and prealbumin levels were measured using an AU5800 Automated Chemistry Analyzer (Beckman Coulter, High Wycombe, UK). Serum levels of IL-6 and procalcitonin (PCT) were measured using a Cobas 601 chemiluminescent immunoassay (Roche, Germany). Plasma D-dimer and fibrinogen levels were measured using a CS 2500 Automated Coagulation Analyzer (Sysmex Corporation, Japan). NLR was calculated by dividing the neutrophil count by the lymphocyte count, and C-reactive protein to albumin ratio (CAR) was calculated by dividing the CRP level by the albumin level. CPAR was calculated by dividing the CRP level by the prealbumin level. The P/F ratio was determined by blood gas analysis with PaO₂/FiO₂.

Pan K., Jin Y., Du W., Wang M., Zhang Y., Liu S, & Zhang Y. (2024). Prognostic value of the neutrophil-to-lymphocyte ratio and C-reactive-protein-to-prealbumin ratio in hospitalized older patients with coronavirus disease 2019. Medicine, 103(16), e37809.

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Comprehensive COVID-19 Diagnostic Biomarkers

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At the first admission of the patients, complete blood count parameters, serum
CRP, procalcitonin (PCT), ferritin, lactate dehydrogenase (LDH), urea,
creatinine, total bilirubin (T.Bil), D-dimer, ALT, AST, CK and highly sensitive
troponin I (hs-TNI) were determined. Complete blood count parameters were
assessed by the UniCel DxH 800 hematology analyzer (Beckman Coulter, Miami, FL,
USA) was employed; serum D-dimer levels by the CS 2500 automated coagulation
analyzer (Sysmex Corporation, Kobe, Japan); serum PCT and hs-TNI levels by th
ADVIA Centaur XP immunoassay analyzer (Siemens Healthineers, Erlangen, Germany)
and serum CRP, ferritin, ALT, AST, urea, creatinine, LDH, CK, T.Bil levels by
the AU 5800 chemistry analyzer (Beckman Coulter, High Wycombe, UK).
SARS-CoV-2 nucleic acid amplification tests in throat swab specimens were
performed by reverse transcription real-time polymerase chain reaction (RT-PCR)
with the Bio-Speedy COVID-19 RT-qPCR kit(Bioeksen R&D Technologies Ltd.,
Istanbul, Turkey).

Colak A., Oncel D., Altın Z., Turken M., Arslan F.D., Iyilikci V., Yilmaz N., Oncel G, & Kose S. (2022). Usefulness of laboratory parameters and chest CT in the early diagnosis of COVID-19. Revista do Instituto de Medicina Tropical de São Paulo, 64, e28.

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