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Tail cuff plethysmograph

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The Tail-cuff plethysmograph is a lab equipment used to measure the blood pressure in small animals, such as mice or rats. It utilizes a cuff placed around the animal's tail to detect changes in blood volume, which are then used to calculate the blood pressure.

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Lab products found in correlation

Ms550d, by Fujifilm (3 mentions)

2 protocols using tail cuff plethysmograph

1

Tail-cuff Blood Pressure Monitoring

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Blood pressure was measured using a tail‐cuff plethysmograph (Visitech Systems). This plethysmograph allows the recordings of systolic and diastolic blood pressures which allows the calculation of mean arterial pressure (MAP) using its Analysis Software. Mice were trained for tail‐cuff blood pressure measurements 1 week before starting the experiments. Blood pressure measurements were performed at the same time of the day (11 AM to 1 PM) to standardize for the influence of the circadian cycle on blood pressure. The average blood pressure was obtained by calculating the average readings of 10 measurements for a single trial. Blood pressure was measured one day before the start of minipump implantation (0 day, considered as baseline) and then on days 7, 14, 21, and 28 of the 4‐week experimental period.
Majid D.S., Mahaffey E., Castillo A., Prieto M.C, & Navar L.G. (2021). Angiotensin II‐induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor‐alpha type 1 receptor. Physiological Reports, 9(16), e14990.
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2

Echocardiographic Analysis in Mice

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Echocardiographic analysis was performed using a Vevo2100 echocardiography machine (VisualSonics, Toronto, Canada) and a linear-array 40MHz transducer (MS-550D). LV systolic and diastolic measurements were captured in M-mode from the parasternal short axis. Tissue Doppler was used to measure diastolic dysfunction in a subset of mice at Day 28. All echocardiography was performed in a blinded fashion. Systolic/diastolic blood pressure and resting heart rate were evaluated by a non-invasive tail cuff plethysmograph, on which mice were trained prior to measurements (Visitech Systems, Apex, NC).
Burke R.M., Lighthouse J.K., Mickelsen D.M, & Small E.M. (2019). Sacubitril/valsartan decreases cardiac fibrosis in left ventricle pressure overload by restoring PKG signaling in cardiac fibroblasts. Circulation. Heart failure, 12(4), e005565.
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