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1 ethyl 3 3 dimethylaminopropyl carbodiimide hydrochloride edc hcl

Manufactured by Sinopharm
Sourced in China

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC·HCl) is a chemical compound commonly used as a coupling agent in various laboratory applications. It facilitates the formation of amide bonds between carboxyl groups and primary amine groups. EDC·HCl is a white crystalline solid that is soluble in water and other polar solvents.

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2 protocols using 1 ethyl 3 3 dimethylaminopropyl carbodiimide hydrochloride edc hcl

1

Synthesis and Characterization of Cumyl Dithiobenzoate

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The synthesis of cumyl dithiobenzoate (CDB) was conducted according to the literature procedure.[34 (link)] 1-Bromohexane, hydroxyethyl methylacrylate (HEMA), 2,4-dihydroxybenzaldehyde, tetrabutylammonium hexafluorophosphate (TBAPF6) and 3,4-diaminobenzoic acid, (≥98%) were purchased from J&K Chemical (China) and used as received. Tetrahydrofuran (THF) was refluxed over potassium/benzophenone until the solution turned blue and distilled before use. 2,2′-Azobis(2-methylpropionitrile) (AIBN, 99%) was recrystallized twice from ethanol and dried under vacuum at room temperature. Di-tert-butyl dicarbonate, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC·HCl), trifluoroacetic acid, K2CO3, KI, Ni(CH3COO)2·4H2O, Cu(CH3COO)2·4H2O, Zn(CH3COO)2·4H2O, and triethylamine were purchased from Sinopharm Chemical Reagent limited corporation (China) and used as received.
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2

Poly γ-glutamic acid and ε-Polylysine Modification

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Poly γ-glutamic acid was provided from Shineking Biotechnology (Nanjing, China). ε-Polylysine was offered from Silver-Elephant Bio-engineering Co. (Zhejiang, China). 4-Morpholineethanesulfonic acid (MES), N-hydroxysuccinimide (NHS), and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC·HCl) were supplied from Sinopharm Chemical Reagent Co. (Shanghai, China), respectively. NaCl, CaCl2, and CrCl3·6H2O were purchased from Sinopharm group Co., Ltd. (Shanghai, China).
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