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Grafton

Manufactured by Medtronic
Sourced in United States

Grafton is a lab equipment product developed by Medtronic. It is designed to facilitate laboratory procedures and analysis. The core function of Grafton is to provide a reliable and efficient platform for various laboratory tasks, but a detailed description while maintaining an unbiased and factual approach is not available.

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9 protocols using grafton

1

Oblique Lumbar Interbody Fusion at L5-S1

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We performed OLIF at L5–S1 [10 (link)]. The patient position was the same as the position of OLIF at L1–L5. We inserted a round-shaped PEEK cage (Perimeter, Medtronic, USA) with 12° lordotic angle into the center of the disc space in an oblique direction. Demineralized bone matrix (Grafton, Medtronic, USA) was also used as fusion material.
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2

Oblique Lumbar Interbody Fusion

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We performed OLIF at L1–L5 [10 (link)]. Patients were positioned in the right lateral decubitus position without hip flexion. A large rectangular polyether-ether ketone (PEEK) cage (Clydesdale, Medtronic, USA) with 6° or 12° lordotic angle and 20 mm width was inserted into the disc space. We used a 6° cage for the L1–L3 levels and a 12° cage for the L3–L5 levels to make a greater lordotic angle at the lower lumbar levels. The cage was filled with demineralized bone matrix (Grafton, Medtronic, USA) for bone fusion. We tried to insert the cages anteriorly close to the anterior disc margin for more posterior shortening by rod compression.
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3

Posterior Lumbar Decompression and Fusion

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In contrast, during this procedure, a midline skin incision was first created, and the muscle fascia was incised in line with the skin incision; then, the spinous process and interspinous ligament complex were identified. Meticulous dissection was performed through the proximal facet to distal facet joint with a Bovie dissector, and decompression was completed, including removal of the inter-spinous ligament complex. Inter-body fusion with cage was performed with harvested lamina and facet bone and demineralized bone matrix (Grafton; Medtronic, Minneapolis, MN, USA). Bilateral pedicle screws were placed at the anatomical position on the corresponding level manually, and correct screw position was confirmed with fluoroscopy (Fig. 1b).
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4

Lateral Lumbar Interbody Fusion Technique

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This technique was performed by the author (W.L.). The patient was placed in the right lateral decubitus position. The surgical approach was performed to reach the retroperitoneal corridor between the psoas muscle and great vessels. The self-retaining retractor was placed upon the operated disk level after sequential dilators were applied. Thorough discectomy and endplate preparation were performed using the orthogonal maneuver. The appropriate-sized cage (CLYDESDALE; Medtronic) filled with DBM (GRAFTON; Medtronic) was inserted orthogonally into the operated disk space. Percutaneous posterior instrumentation was placed in prone position after completion of the lateral procedure.
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5

OLIF25 Surgical Technique

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The surgical technique for OLIF25 has been published previously.6) (link) Briefly, patients were positioned in the right lateral decubitus position under general anesthesia. Using C-arm imaging, a 4–5 cm oblique skin incision was made from the anterior margin of the target disc. The external oblique, internal oblique, and transverse abdominis muscles were split along directions of muscle fibers. The target disc was approached anteriorly through the retroperitoneal space, and a cage (Clydesdale; Medtronic, Minneapolis, MN, USA) packed with a demineralized bone matrix (Grafton; Medtronic, Minneapolis, MN, USA) was inserted using an orthogonal maneuver after the disc was removed. In case of multilevel surgery, the operation was performed from the lowest disc and proceeded upward by the same way as mentioned herein.
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6

Minimally Invasive Lateral Interbody Fusion

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OLIF involves minimally invasive lateral interbody fusion using a left-sided retroperitoneal approach and percutaneous pedicle screw fixation.
The intervertebral disc was exposed through an open corridor between the psoas muscle and aorta. The sympathetic chain and ureter were mobilized anteriorly. The procedure was performed using an OLIF system (Medtronic, Memphis, TN, USA), fusion material (Grafton, Medtronic, Memphis, TN, USA), and a percutaneous pedicle screw fixation system (Longitude system, Medtronic, Memphis, TN, USA). We determined the height of the cage to be inserted by using the presurgery CT scan. If the intervertebral disc space was < 6 mm, a 10-mm cage was inserted. If the intervertebral disc space was ≥ 6 mm, a cage 4 mm greater than the disc height was inserted. The indirect decompression effect on the constant disc height was evaluated. We did not perform posterior decompression on any of the patients.
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7

Minimally Invasive Lateral Lumbar Interbody Fusion

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After general anesthesia was done, the patient was positioned in the right lateral decubitus position. The targeted intervertebral disc levels were checked using the C-arm fluoroscope, and skin marking was done. A skin incision was made along the anterolateral part of the abdomen, corresponding to the skin marking of the targeted disc. The external oblique, internal oblique, and transverse abdominis muscles were bluntly dissected layer by layer to access the retroperitoneal space. The operated intervertebral disc was identified and prepared for the discectomy. In cases where the patient had no or a narrow surgical corridor, the sponge and retractor were used to retract the psoas muscle posteriorly in order to create a working space between the great vessel and the psoas muscle (Figure 3). The self-retaining tubular retractors were then applied to the created corridor before disc space preparation. After discectomy and endplate preparation were done, the appropriate-size cage filled with demineralized bone matrix (DBM; GRAFTON®, Medtronic, Minneapolis, MN, USA) was inserted in the disc space. Finally, the percutaneous posterior fixation with percutaneous pedicle screws and rods was done.
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8

Surgical Technique for Oblique Lumbar Interbody Fusion

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The surgical technique used for OLIF has been previously described at our institute [13 (link),14 (link),20 (link)]. The patients were briefly placed in the right lateral decubitus position for the left-sided retroperitoneal approach. The surgical level of the disc was marked on the skin in true lateral view under C-arm fluoroscopy. An oblique skin incision was made 3–5 cm ventral to the anterior margin of the intervertebral disc. After dissecting the 3 layers of the abdominal wall muscles, the peritoneal fat was identified. The disc annulus was exposed through an open corridor between the psoas muscle and peritoneum. At the anterior border of the psoas muscle, the plane between the disc annulus and the psoas muscle was bluntly dissected using a peanut gauze ball to not injure the psoas muscle bundle. A slight dorsal retraction of the psoas muscle was applied during tubular retractor fixation. The entire surgery was performed using a Medtronic OLIF system (Medtronic, Memphis, TN, USA) with a minimally invasive tubular retractor, fusion material (Grafton, Medtronic), and a percutaneous pedicle screw fixation system (either Sextant or Longitude system, Medtronic) (Fig. 1). Posterior decompression was not performed on any of the patients included in this study.
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9

Minimally Invasive Transforaminal Lumbar Interbody Fusion

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During this procedure, a lateral skin incision was created on the symptomatic side. The muscle fascia was incised in line with the skin incision, and the muscle plane between the multifidus and longissimus muscles was identified with a gloved finger. Dilating instrument retractors (METRx; Medtronic, Minneapolis, MN, USA) were attached, and a decompression maneuver was completed. Inter-body fusion with cage was performed with harvested lamina and facet bone and demineralized bone matrix (Grafton; Medtronic, Minneapolis, MN, USA). For percutaneous pedicle screw fixation, a contralateral skin incision was made through the intermuscular plane, bilateral pedicle screws were placed on the corresponding level, and a rod was inserted percutaneously under fluoroscopic guidance (Longitude; Medtronic, Minneapolis, MN, USA) (Fig. 1a).

MI TLIF approach (a) and conventional TLIF approach (b).

Figure 1
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