Iu22 system

Manufactured by Philips

Sourced in United States, Italy

The Philips IU22 system is an advanced ultrasound imaging device designed for a wide range of clinical applications. It features high-resolution imaging capabilities and a versatile platform to support various diagnostic procedures.

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Lab products found in correlation

Logiq e9 system, by GE Healthcare (2 mentions) Mylab 90, by Esaote (2 mentions) Sonovue contrast agent, by Bracco (1 mentions) Ge voluson 730, by GE Healthcare (1 mentions) Sonovue, by Bracco (1 mentions) Resona 7, by Mindray (1 mentions) Acuson sequoia 512 scanner, by Siemens (1 mentions) L12 5 linear transducer, by Philips (1 mentions) Aplio 500, by Toshiba (1 mentions)

Spelling variants of this product

IU22 ultrasound system (97 citations) IU22 US system (8 citations) IU22 xMATRIX ultrasound system (8 citations) Ultrasound Systems IU22 (2 citations) IU22 Colour Doppler Ultrasound System (2 citations) IU22 ultrasonography system (2 citations)

26 protocols using iu22 system

Prostate Vascularization Imaging Before and After TPLA

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Grayscale TRUS and CEUS images of the prostate were simultaneously acquired using the MyLab Eight eXP system (Esaote, Florence, Italy) with a 4 MHz TRT33 biplane probe and the Philips IU22 system (Phillips Healthcare, Bothell, WA, USA) with a 3.5 MHz C10-3V endocavity probe. This was performed before, during, immediately after, and 4 wk after TPLA, which was 1–3 d prior to RARP. Periprocedural prostate vascularization was demonstrated by CEUS in combination with a 2.4 ml intravenous bolus injection, followed by 1 ml/min continuous infusion of the Sonovue contrast agent (Bracco, Milan, Italy) using the VueJect infusion pump (Bracco).
CEUS recordings before and after TPLA were acquired with a 9 Hz frame rate by experienced operators (>200 TRUS procedures per year) and were preceded by intravenous bolus injections of 2.4 ml the Sonovue contrast agent (Bracco, Milan, Italy) and 5 ml saline flush. Transverse and sagittal sweeps were acquired for segmentation and three-dimensional (3D) reconstruction when wash-in of contrast agent was completed, based on visual inspection.

van Riel L.A., van Kollenburg R.A., Freund J.E., Almasian M., Jager A., Engelbrecht M.R., Smit R.S., Bekers E., Nieuwenhuijzen J.A., van Leeuwen P.J., van der Poel H., de Reijke T.M., Beerlage H.P., Oddens J.R, & de Bruin D.M. (2023). Reliable Visualization of the Treatment Effect of Transperineal Focal Laser Ablation in Prostate Cancer Patients by Magnetic Resonance Imaging and Contrast-enhanced Ultrasound Imaging. European Urology Open Science, 54, 72-79.

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Hemodialysis Access Monitoring Protocol

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The prespecified trial protocol dictated a follow-up period of 12 months. At the haemodialysis unit, monthly recordings of volume flow (Transonic HD03 Hemodialysis Monitor; Transonic Systems Inc., Ithaca, NY, USA) were undertaken as part of routine care. If large flow reductions were noticed (i.e. >50% as prespecified), a duplex ultrasound examination was performed (Philips iU22 system; Philips Healthcare). Ultrasound was also performed when clinical haemodialysis access related problems were detected regardless of volume flow measurements. When duplex ultrasound indicated a significant stenosis or restenosis, corresponding to clinical or functional issues, the patient was scheduled for a new endovascular procedure. No regularly timed prespecified investigations were performed, other than volume flow measurements, as was the standard clinical practice.

Fransson T., Gottsäter A., Abdulrasak M., Malina M, & Resch T. (2022). Drug-eluting balloon (DEB) versus plain old balloon angioplasty (POBA) in the treatment of failing dialysis access: A prospective randomized trial. The Journal of International Medical Research, 50(3), 03000605221081662.

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Carotid and Vertebral Artery Ultrasound Protocol

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For CDU, an iU22 system (Philips Healthcare, Bothell, WA) with a 9-3 MHz linear array probe and 5-1 MHz curvilinear array probe was used. According to the ultrasound protocol previously described by Pellerito (21 ), all CDUs were performed by the same physician (Z. J.), who had 8 years of experience in vascular ultrasonography, had performed more than 2000 vascular cases per year, and who was unaware of the patient's clinical data (other imaging data, physical examination results, laboratory results, and patient history). The ultrasound parameters measured were peak systolic velocity (PSV) and acceleration time (AT) at the stenotic segment of the SA, peak systolic velocity (PSVd) and acceleration time (ATd) at the distal segment of the SA, and peak reversed velocity (PRV) of the VA. The spectral waveforms of the stenotic SA, distal SA, and VA were recorded. The ratios of PSV to PSVd (PSVr) and ATd to AT (ATr) were also calculated. AT represents the time from systolic acceleration to peak flow. PRV represents the value from the baseline to the reversed systolic peak of VA. The waveforms of the stenotic and distal SA included the triphasic, biphasic, and monophasic waveforms. The waveforms of the VA included the unchanged, mid-systolic notch, bidirectional, and completely retrograde waveforms (Figure 2).

Zhang J., Wang L., Chen Y., Wang S., Xing Y, & Cui L. (2022). Color Doppler Ultrasonography for the Evaluation of Subclavian Artery Stenosis. Frontiers in Neurology, 13, 804039.

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Ultrasound-Based Hepatic Steatosis Assessment

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Abdominal ultrasound scans were performed on all participants. We used the iU22 system (Philips Ultrasound, Bothell, WA) with a C5-1 pure wave transducer (5–1 MHz) or the LOGIQ E9 system (GE Medical Systems, Inc, Wauwatosa, WI) with a C1-5 transducer (1–6 MHz) to scan the liver.
The diagnosis of hepatic steatosis was made on the basis of 5 known criteria: namely, liver to kidney contrast, brightness of the liver parenchyma, deep beam attenuation, echogenic walls in the small intrahepatic vessels, and definition of the gallbladder wall. Based on these findings, and using a standardized algorithm, we categorized the degree of steatosis as a 4-level variable (none, mild, moderate, or severe).^{16 (link),17}

Ze E.Y., Kim B.J., Jun D.H., Kim J.G., Kang H, & Lee D.Y. (2017). The Fatty Liver Index: A Simple and Accurate Predictor of Colorectal Adenoma in an Average-Risk Population. Diseases of the Colon and Rectum, 61(1), 36-42.

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Standardized Ultrasound Evaluation of AVF

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Ultrasound images were obtained at 1 day and 6 weeks after the AVF creation surgery for the HFM study patients and at 6 weeks and 6 months postoperatively for the ancillary study patients. All ultrasound examinations were performed using the iU22 system (Philips Healthcare, Andover, MA) by registered vascular sonographers who received dedicated training by the HFM Ultrasound Core on standardization of blood flow rate acquisition and methods to minimize errors.^{17 (link)} For this reason, intra- and inter-sonographer variability was not examined further.
At each visit, the blood flow measurement was repeated three times at a location 2 cm proximal to the anastomosis in the proximal artery (PA) and 10 cm distal to the anastomosis in the draining vein (DV, Fig 1). The sample volume included the whole lumen (Fig 2, A) except in rare cases where the lumen was larger than the ultrasound machine’s maximal sample volume. Cross-sectional images were also obtained at these sites for determination of the lumen diameter. Since all ultrasound images gave us interpretable results, we did not discard any DUS flow measurements.

He Y., Shiu Y.T., Pike D.B., Roy-Chaudhury P., Cheung A.K, & Berceli S.A. (2018). Comparison of hemodialysis arteriovenous fistula blood flow rates measured by Doppler ultrasound and phase-contrast magnetic resonance imaging. Journal of vascular surgery, 68(6), 1848-1857.e2.

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Sonographic Examination of Thyroid Nodules

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During the sonographic examination, the patient was in the supine position, with the neck fully exposed. Both gray scale and color Doppler examinations were performed with a 4- to 13-MHz linear probe (MyLab 90; EsaoteSpA, Genoa, Italy; iU22 system, Philips, Seattle, WA) by 2 radiologists with more than 5 years of experience in thyroid imaging. The focus, gain, and depth were adjusted to obtain the best image. Doppler parameters were optimized to maximize Doppler sensitivity in the absence of any color noise in normal thyroid tissue. Images of each suspicious nodule were obtained both in transverse and longitudinal orientations. The patients who had nodules with no malignant features needed a regular follow up every 6 months. If the size of nodule remained stable, further follow-up was performed. All images were recorded and uploaded to a picture archiving and communication system for further analysis.

Ni X., Xu S., Zhang B., Zhan W, & Zhou W. (2022). Clinical and Sonographic Features of Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features: A Retrospective Study. Ultrasound Quarterly, 39(1), 23-31.

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Ultrasound Criteria for Hepatobiliary Conditions

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Ultrasound was part of the routine examination and was performed by 2 experienced ultrasound radiologists with at least 5 years of experience using an IU 22 system (Philips, Best, Netherlands). An individual was diagnosed with gallbladder stones when the ultrasound examination showed a strong echogenic light group in the gallbladder followed by a sound shadow, which moved with a change in body position. An individual was diagnosed with gallbladder polyps when the ultrasound examination showed that papillary or mulberry-like nodules protruded into the gallbladder with strong or medium echoes and did not change with body position. An individual was diagnosed with fatty liver when the ultrasound examination showed that the liver had fatty liver changes (hyperechogenicity due to increased acoustic interface caused by the intracellular accumulation of lipid vesicles, blurring of vascular margins, increased liver size, and increased acoustic attenuation). Dyslipidemia diagnosis was determined using the “Guidelines for the Prevention and Treatment of Dyslipidemia in Chinese Adults” developed by the Chinese Cardiovascular Disease Association in 2007. Diabetes (DM) and hypertension diagnoses were made using 1999 World Health Organization standards. Obesity and overweight diagnoses were made using WHO recommendations (overweight: BMI ≥24 kg/m²; obesity: BMI ≥28 kg/m²).

Zhang X., Guan L., Tian H, & Li Y. (2022). Prevalence and Risk Factors of Gallbladder Stones and Polyps in Liaoning, China. Frontiers in Medicine, 9, 865458.

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Ultrasonography for Carotid Artery Stenosis

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All participants underwent high-resolution B-mode ultra-sonography of their extracranial arteries. All arterials scans were performed by two independent sonographers using the iU-22 system (Philips Medical Systems, Bothell, WA, USA). The sonographers were blinded to the participants’ baseline information. CAS was defined according to the diagnostic criteria of the Radiological Society of North America.16 (link) Briefly, stenosis was defined as peak systolic velocity (PSV) ≥125 cm/s in the presence of an atherosclerotic lesion or a maximum diameter reduction of ≥50%. Participants with PSV <125 cm/s and no signs of atherosclerotic lesions were considered to be without stenosis.17 (link)

Zhu B., Zhang L., Cheng X.P., Wang L., Tian Y., Li X.X., Liu Y.P, & Zhao Z.G. (2018). The association between metabolic syndrome and asymptomatic carotid artery stenosis in menopausal women: a cross-sectional study in a Chinese population. Therapeutics and Clinical Risk Management, 14, 2183-2188.

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Multimodal Imaging of Abnormal Placenta

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Abdominal ultrasound and MRI were performed by obstetricians or radiologists experienced in abnormal adherent placenta. Ultrasounds were performed using the equipment including the IU 22 system (Philips Medical Systems, Bothell, WA) and the GE Voluson 730 or E8 (GE Medical Systems, Zipf, Austria) with 4 to 9 MHz or 5 to 9 MHz transabdominal transducers, and 3 to 9 MHz and 4 to 8 MHz endovaginal transducers. MRI was performed with a 1.5 Tesla scanner General Electric (GE Healthcare, Waukesha, WI). The MRI protocols were similar in both hospitals and included T1-weighted sequences and T2-weighted MR sequences. Seven MRI scans were done after intravenous injection of gadolinium, 6 were MR diffusion-weighted imaging. Abdominal ultrasound images and MRI were blindly estimated by 3 experienced obstetricians and radiologists with >10 years of evaluation experience of placentation disorders, respectively.

Xia H., Ke S.C., Qian R.R., Lin J.G., Li Y, & Zhang X. (2020). Comparison between abdominal ultrasound and nuclear magnetic resonance imaging detection of placenta accreta in the second and third trimester of pregnancy. Medicine, 99(2), e17908.

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Contrast-Enhanced Ultrasound Imaging Protocol

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BMUS and CEUS examinations were performed by experienced radiologists using a LOGIQ E9 system (GE Healthcare, Milwaukee, WI, USA) equipped with a C1-6 abdominal convex probe and an iU22 system (Philips Bothell, Washington, USA) equipped with a C5-1 convex array transducer. A dose of 1.5~2.4 ml of SonoVue (Bracco, Milan, Italy) was antecubitally injected and immediately followed by a 5.0-ml saline injection. Images were continuously recorded for at least 4~6 min post-injection and stored as digital cine clips.

Chen Y., Lu Q., Zhang W., Cao J., Dong Y, & Wang W. (2022). Preoperative Differentiation of Combined Hepatocellular-Cholangiocarcinoma From Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: A Nomogram Based on Ultrasonographic Features and Clinical Indicators. Frontiers in Oncology, 12, 757774.

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