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Theophylline tp

Manufactured by Merck Group
Sourced in United States, United Kingdom

Theophylline (TP) is a chemical compound used in various laboratory applications. It is a crystalline substance that is soluble in water and organic solvents. TP is commonly used as a reference standard in analytical techniques such as high-performance liquid chromatography (HPLC) and spectrophotometry for the quantification of theophylline in biological samples.

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2 protocols using theophylline tp

1

Theophylline-loaded Polymeric Hydrogel Synthesis

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Theophylline (TP) was obtained from Sigma-Aldrich (St. Louis, MI, USA). Poly(aspartic acid) (ASPA, MW: 133.10, purity = 99 plus%) was purchased from ACROS, NJ, USA. Moreover, 2-acrylamido-2-methylpropanesulfonic acid (AMPS) (purity = 98%) and N,N′-methylene bisacrylamide (MBA, purity = 97%) were procured from Alfa Aesar (Lancashire, UK). Similarly, ammonium peroxodisulfate (APS) (purity = 98%) and sodium hydrogen sulfite (SHS) (purity = 58.5%) were acquired from Showa (Tokyo, Japan) and Avantor Performance Materials (LLC, Radnor, Italy), respectively.
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2

Ternary Amorphous Solid Dispersions

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Flufenamic acid form I (FFA I), Nicotinamide (NIC) (≥99.5% purity) and Theophylline (TP) (≥99.5% purity) were purchased from Sigma-Aldrich (Dorset, UK). Poly (ethylene glycol) 4000 (PEG) was purchased from Sigma-Aldrich (Dorset, UK). Plasdone K-29/32 (PVP) and Plasdone S-630 (PVP-VA) were gifts from Ashland Inc. (Schaffhausen, Switzerland). Methanol (HPLC grade) and ethanol (lab grade) were purchased from Fisher Scientific UK (Loughborough, UK) and used as received. Double distilled water was generated from a Bi-Distiller (WSC044.MH3.7, Fistreem International Limited, Loughborough, UK) and used throughout the study.
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