MI was induced by ligation of the left coronary artery using an 8–0 polypropylene suture through left thoracotomy under 1.0% isoflurane anesthesia and mechanical ventilation9 (link), 32 (link). At 20 minutes or Day 28 after coronary artery ligation (a model for the treatment of acute MI or post-MI chronic heart failure, respectively), IL-4c (5 μg of recombinant mouse IL-4 [PeproTech, 214-14] mixed with 25 μg of a neutralizing monoclonal anti-IL-4 antibody [BD Biosciences, 554387] dissolved in 100 μl of phosphate-buffered saline [PBS]) was injected into the peritoneal cavity of the mice). IL-4c is known to have an expanded in-vivo half-life of IL-4 (over 24 hours versus 30 minutes for sole protein)17 (link), 25 (link). An equivalent volume of PBS was injected in a similar method as a control.
Neutralizing monoclonal anti il 4 antibody
Manufactured by BD
Neutralizing monoclonal anti-IL-4 antibody is a laboratory reagent used for research purposes. It is an antibody that binds to and neutralizes the cytokine interleukin-4 (IL-4). This antibody can be utilized in various in vitro and in vivo experimental models to study the biological functions of IL-4.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using neutralizing monoclonal anti il 4 antibody
1
Interleukin-4 Complex Cardiac Repair Protocol
2
Interleukin-4 Complex Cardiac Repair Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
MI was induced by ligation of the left coronary artery using an 8–0 polypropylene suture through left thoracotomy under 1.0% isoflurane anesthesia and mechanical ventilation9 (link), 32 (link). At 20 minutes or Day 28 after coronary artery ligation (a model for the treatment of acute MI or post-MI chronic heart failure, respectively), IL-4c (5 μg of recombinant mouse IL-4 [PeproTech, 214-14] mixed with 25 μg of a neutralizing monoclonal anti-IL-4 antibody [BD Biosciences, 554387] dissolved in 100 μl of phosphate-buffered saline [PBS]) was injected into the peritoneal cavity of the mice). IL-4c is known to have an expanded in-vivo half-life of IL-4 (over 24 hours versus 30 minutes for sole protein)17 (link), 25 (link). An equivalent volume of PBS was injected in a similar method as a control.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!