All MRI images were collected using a
GE 3T MRI scanner (GE Medical Systems, Milwaukee, WI) equipped with a standard head coil. Participants were asked to remain awake, relaxed, keep their eyes closed, and not to do any specific thinking during functional data collection. Conventional imaging sequences, which included T1-weighted images and T2-FLAIR images, were acquired for each subject to detect clinically asymptomatic lesions.
Using an echo-planar imaging (EPI) sequence, the rs-fMRI data were obtained with the following parameters: repetition time (TR)/echo time (TE) = 3,000 ms/40 ms, flip angle = 90°, 25 slices, thickness/gap = 5/0 mm, matrix size = 96 × 96, and field of view = 24 × 24 cm, 128 time points. Each scan lasted ~6 min.
Three-dimensional brain high-resolution T1-weighted structural images were acquired using a 3D magnetization-prepared rapid-acquisition gradient-echo (3D-MPRAGE sequence). The parameters are as follows: 176 sagittal slices, TR = 5.6 ms, TE = 1.7 ms, matrix = 256 × 256, (FOV) = 25.6 × 25.6 cm, and thickness/gap = 1.2/0 mm. This session lasted for ~5 min.
Ma C., Tian F., Ma M.G., Su H.W., Fan J.C., Li Z.H, & Ren Y.D. (2020). Preferentially Disrupted Core Hubs Within the Default-Mode Network in Patients With End-Stage Renal Disease: A Resting-State Functional Magnetic Resonance Imaging Study. Frontiers in Neurology, 11, 1032.