The embolization procedure was performed by the neurointerventionists. All procedures were performed under general anesthetics following surgical evacuation during the same hospital admission. Systemic heparinization was not used. Femoral or radial access was employed at the discretion of the treating neurointerventionist. Common carotid and external carotid angiography were performed using a standard 5 or 6 French catheter. Under roadmap guidance, a microcatheter (Headway Duo 167, Terumo Microvention) or balloon microcatheter (Scepter XC, Scepter mini, Terumo Microvention) with guidewire was advanced into the MMA. MMA angiography was then performed to identify both frontal and parietal branches as well as to exclude potential dangerous anastomoses. Embolization was performed with one of the following embolic agents including Squid-12 (Balt, Montmorency, France), Onyx-18 (Medtronic, Irvine, CA, USA), Phil 25% (MicroVention, Aliso Viejo, USA), and 25% n-butyl cyanoacrylate (n-BCA) (B. Braun, Melsungen, Germany) with 75% Lipiodol (Guerbet, Villepinte, France), at the discretion of the treating neurointerventionist. When anterograde flow through MMA branches was no longer visible, the procedure was concluded.
Onyx 18
Manufactured by Medtronic
Sourced in France, United States
The Onyx-18 is a compact and versatile lab equipment designed for use in various scientific and research settings. It serves as a centrifuge, enabling the separation of different components within a liquid sample through the application of controlled centrifugal force. The Onyx-18 is capable of processing a range of sample volumes and can be programmed to operate at specific speeds and durations to meet the requirements of diverse laboratory procedures.
Automatically generated - may contain errors
Lab products found in correlation
3 protocols using onyx 18
1
MMA Embolization Procedure Protocols
2
Onyx Embolization through Microcatheter
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A dimethyl sulphoxide-compatible microcatheter (detachable tip: Apollo, Ev3, Irvine, California, USA or Sonic, Balt Extrusion, Montmorency, France//non-detachable tip: Echelon-10, Ev3-Covidien, Dublin, Ireland) was advanced to the respective feeder artery. A second microcatheter (Magic 1.2FM, Balt Extrusion, Montmorency, France or Echelon-10) was positioned alongside the primary microcatheter, with its tip slightly further distal to the detachment zone marking. The plug was formed by injecting coils and a subsequent mixture of acrylate glue (Histoacryl, B. Braun, Melsungen, Germany) and iodized oil (Lipiodol Ultra Fluide, Guerbet, France) in a ratio of 1:2 through the secondary microcatheter. The second microcatheter was removed after coil/glue delivery and plug completion. Following plug formation, continuous anterograde injection of the Onyx 18 (Medtronic, Irvine, California, USA) was performed via the primary microcatheter. Whenever possible, the primary microcatheter was withdrawn completely after nidus occlusion. In cases of microcatheter entrapment, however, the detachable tip remained in situ. Following the intervention, patients underwent post-operative MRI and neurological monitoring while hospitalized.
3
Embolization of Low-grade Brain AVMs
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Informed consent was obtained from all patients or their next of kin. The goal of the procedure was to cure low-grade bAVMs in one session, if possible, or in multiple sessions. All procedures were performed under general anesthesia using a biplane flat-panel angiographic suite (Artis zee with PURE, Siemens). Patients were heparinized with 2500-5000 U after the femoral or radial puncture. Depending on the accessibility and angioarchitecture of the bAVM, an arterial or venous approach was considered and undertaken. The most common arterial access was femoral before 2019, and it was changed to radial access for most cases after 2019. A direct puncture of the internal jugular vein was used for the venous approach. A transvenous approach was considered if we did not find a safe transarterial approach for EVT. All bAVMs were embolized by injection of liquid embolic agents, including Onyx-18 (Medtronic), Squid-18 (Emboflu), and Glubran 2 (GEN). All patients were transferred to the ICU after the procedure, and systolic blood pressure was maintained at less than 90 mm Hg for 24 hours. In patients who underwent multiple sessions, the interval between sessions was 6-12 weeks.
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