Ikk inhibitor bay 117085

Manufactured by Cayman Chemical

Sourced in United States

IKK inhibitor Bay 11-7085 is a small molecule that inhibits the IKB kinase (IKK) enzyme complex. The IKK complex plays a crucial role in the activation of the NF-kB signaling pathway.

Automatically generated - may contain errors

Lab products found in correlation

Antibody against actin, by Merck Group (1 mentions) Tasquinimod, by Selleck Chemicals (1 mentions) Horseradish peroxidase hrp conjugated secondary antibody, by Santa Cruz Biotechnology (1 mentions) Ci994, by Selleck Chemicals (1 mentions) Nexturastat a, by Selleck Chemicals (1 mentions) Sc 33020, by Santa Cruz Biotechnology (1 mentions) Sc 372, by Santa Cruz Biotechnology (1 mentions) Iκbα sc 371, by Santa Cruz Biotechnology (1 mentions) Sc 7178, by Santa Cruz Biotechnology (1 mentions) Bortezomib, by Selleck Chemicals (1 mentions)

2 protocols using ikk inhibitor bay 117085

Epigenetic Regulation in Cells

Check if the same lab product or an alternative is used in the 5 most similar protocols

Antibodies against human p65 NFκB (sc-372), K9/14 acetylated histone H3 (sc-8655), HDAC1 (sc-81598), HDAC2 (sc-6296), HDAC3 (sc-11417), CBP (sc-7300), and p300 (sc-585) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA). Antibody against actin was purchased from Sigma (St. Louis, MO). Horseradish peroxidase (HRP)-conjugated secondary antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA). Romidepsin was from ChemieTek (Indianapolis, IN). CI994, tasquinimod, and nexturastat A were from Selleckchem (Houston, TX). IKK inhibitor Bay 117085 was purchased from Cayman Chemicals (Ann Arbor, MI). All other reagents were molecular biology grade and were from Sigma (St. Louis, MO).

Gatla H.R., Zou Y., Uddin M.M, & Vancurova I. (2017). Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cells. Oncotarget, 8(41), 70798-70810.

+ Open protocol

+ Expand

Characterization of NF-κB signaling components

Check if the same lab product or an alternative is used in the 5 most similar protocols

Purified polyclonal antibodies against human p65 NFκB (sc-372), phosphorylated p65 NFκB at S536 (sc-33020), p50 NFκB (sc-7178), and IκBα (sc-371) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Purified polyclonal antibody against actin was from Sigma (St. Louis, MO, USA). Horseradish peroxidase (HRP)-conjugated anti-rabbit, anti-mouse and anti-goat secondary antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA). Bortezomib was obtained from Selleck Chemicals (Houston, TX, USA). The IKK inhibitor Bay 117085 was purchased from Cayman Chemicals (Ann Arbor, MI, USA). All other reagents were molecular biology grade and were from Sigma (St. Louis, MO, USA).

Singha B., Gatla H.R., Phyo S., Patel A., Chen Z.S, & Vancurova I. (2015). IKK inhibition increases bortezomib effectiveness in ovarian cancer. Oncotarget, 6(28), 26347-26358.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!