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Para aminophenol

Manufactured by Merck Group
Sourced in Germany

Para-aminophenol is a chemical compound used as an intermediate in the production of various pharmaceuticals and dyes. It is a white crystalline solid with a melting point of approximately 184°C. Para-aminophenol is primarily utilized as a precursor in the synthesis of other chemical compounds, but its specific core function is not provided in order to maintain an unbiased and factual approach without extrapolation.

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3 protocols using para aminophenol

1

Synthesis of Organic Compounds

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Meta-aminophenol, para-aminophenol, 4-hydroxycoumarin, acetic acid, methanol, ethanol, toluene, acetone, dimethyl sulfoxide, potassium-tetrachloridopalladate(II), and phosphoryl chloride were obtained from Sigma-Aldrich, Germany.
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2

Characterization of Nanomaterial Coatings

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Vinyltrichlorosilan (VTCS) was obtained from abcr GmbH (Karlsruhe, Germany) and stored under nitrogen.Coverslips of size 26 × 76 mm were purchased from Menzel (Braunschweig, Germany) and para-aminophenol, para-nitrophenol and sodium borohydride were obtained from Sigma-Aldrich (St.Louis, MO, USA) and used as received. The holes in the glass slides were drilled using a KL450 ultrasonic drill (AQUARUS, Pappenheim, Germany). Sputtering targets (Mo, Pt, Ni, Cu, Au) were obtained from BALTIC Preparation e.K (Wetter, Germany). Sputtering was conducted with a CCU-010 HV coating unit (Safematic, Zizers, Switzerland). BLAUBRAND® intraMARK (Brandt GMBH, Wertheim, Germany) 5 µL capillaries were purchased from the University of Zurich supply shop. An IPC high-precision multichannel dispenser (ISM930C) was used as peristaltic pump (Ismatec, Wertheim, Germany). Double distilled water was from a glass double distillery apparatus (GFL, Burgwedel, Germany) and was used to treat the slides prior to coating (SNFs, bagels); all other solutions were prepared from ultrapure water (Simplicity® UV system) (Millipore, Billerica, MA, USA). SEM images were taken on a 450 Zeiss Gemini (Zeiss, Jena, Germany). TEM was performed using a FEI Tecnai G2 Spirit (FEI company, Hillsboro, OR, USA).
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3

Simultaneous Quantification of Analgesics

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Pure samples—drotaverine (DRO) was kindly supplied by Alexandria Pharmaceuticals and Chemical Industries, Alexandria, Egypt. CAF and PCT were kindly supplied by Minapharm Pharmaceutical Company, Cairo, Egypt. Para-aminophenol was purchased from Sigma Aldrich, Germany. The purities were found to be 100.25 ± 0.39, 99.56 ± 0.59, 99.98 ± 0.25 and 99.99 ± 0.39 for DRO, CAF, PCT and PAP respectively.

Market sample—Petro tablets, labelled to contain 40 mg (DRO)/400 mg (PCT)/60 mg (CAF), Soumadril Compound tablets labelled to contain 200 mg Carisopradol (CAR)/160 mg (PCT)/32 mg (CAF) and Panadol Extra tablets labelled to contain 500 mg (PCT)/65 mg (CAF), were purchased from the Egyptian market.

Solvents—Spectroscopic analytical grade methanol (S.d.fine-chem limited-Mumbai).

Stock standard solutions—(1 mg/mL) stock solution of each of DRO, CAF, PCT and PAP in methanol were prepared. The prepared solutions were found to be stable without any degradation when stored in the dark in the refrigerator at 4° C for 1 week except for PAP which should be freshly prepared.

Working standard solutions—(50 μg/mL) working solutions for DRO, CAF, PCT and PAP were prepared from (1 mg/mL) stock solutions by appropriate dilutions with methanol.

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