L-Buthionine-sulfoximine (BSO) was purchased from Santa Cruz Biotechnology (cat#: sc-218630). Reduced GSH and N-Acetyl-L-cysteine (NAC) were purchased from Sigma-Aldrich. Oxaliplatin was provided by Fresenius Kabi (5 mg/mL, Bad Homburg, Germany).
L buthionine sulfoximine bso
Manufactured by Santa Cruz Biotechnology
Sourced in United States
L-Buthionine-sulfoximine (BSO) is a laboratory reagent used in research. It functions as a potent and selective inhibitor of gamma-glutamylcysteine synthetase, a key enzyme in the biosynthesis of glutathione.
Automatically generated - may contain errors
Lab products found in correlation
Reduced gsh, by Merck Group (1 mentions)
N acetyl l cysteine, by Merck Group (1 mentions)
Oxaliplatin, by Fresenius (1 mentions)
D glucose, by Merck Group (1 mentions)
Anhydrous citric acid, by Merck Group (1 mentions)
Pyruvate, by Merck Group (1 mentions)
Oxaloacetic acid, by Merck Group (1 mentions)
Bptes, by Merck Group (1 mentions)
2 protocols using l buthionine sulfoximine bso
1
Inhibition of Glutathione Synthesis
2
Metabolic Modulation via Bioactive Compounds
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Dimethyl-α-ketoglutarate (α-KG), (–)-Epigallocatechinmo nogallate (EGCG), oxaloacetic acid (OAA), pyruvate, Adenosine 5ʹ-triphosphate (ATP), citric acid-anhydrous, glutathione reduced ethyl ester (GSHe), and D-(+)-glucose were purchased from Sigma-Aldrich (USA). L-Buthionine sulfoximine (BSO) was purchased from Santa Cruz Biotechnology (USA). All of above chemicals were diluted with culture medium to the indicated final concentrations just before use. Bis-2-(5-phenylacetamido-1,3,4- thiadiazol-2-yl) ethyl sulfide (BPTES) (Sigma, USA) was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 10 mM. Additional dilutions of BPTES were made in methanol and used at the indicated final concentrations.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!