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As1200

Manufactured by Agilent Technologies

The AS1200 is a high-performance liquid chromatography (HPLC) autosampler designed for efficient sample handling and injection. It features a precise and reliable sample delivery system to ensure accurate and reproducible results.

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4 protocols using as1200

1

Evaluation of Beam Positioning Accuracy

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Figure 1a shows the experimental setup for the evaluation of beam‐positioning accuracy. TrueBeam STx (Varian Medical Systems), with a 2.5 mm leaf‐width HD120 multileaf collimator (MLC) and carbon fiber couch (Brainlab, Munich, Germany), was used to evaluate the beam‐positioning accuracy. A WL test‐dedicated phantom with a 3 mm diameter steel ball (TM‐WINS: R‐Tech Inc., Tokyo, Japan) was placed on the couch top and aligned with the room laser beam. This study evaluated the beam‐positioning accuracy using the WL test and EPID‐based measurements.16 The EPID (aS‐1200, Varian Medical Systems) had a pixel pitch of 0.336 mm and image size of 1190 × 1190 pixels. Here, the EPID was set with a source‐to‐detector distance of 1500 mm and pixel size of 0.244 mm at the isocenter plane. MLC‐shaped square fields of 10 × 10 mm2 were created separately at the isocenter and off‐axis positions. Figure 1b shows an example of an MLC‐shaped square field. Here, MLC‐shaped square fields were created at each off‐axis position (distances of 0, 25, 50, 75, and 100 mm away from the isocenter position) in the Y direction in the beam's eye view (BEV). For each gantry angle, 17 patterns of MLC‐shaped fields were observed at positions of 0, 25, 50, 75, and 100 mm in the X and Y directions.
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2

Comparing MLI and SLI EPID Designs

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The effect of employing MLI structure as opposed to the typical SLI design for GOS EPIDs was studied. The SLI design was based on a Varian AS-1200 where the GOS thickness (NGOS) was approximately 290 μm. The modeled MLI detector is based on the prototype imager, which is installed with 430 μm of GOS in each layer.
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3

Varian's Halcyon Linac for IGRT

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Varian's ring‐shaped Halcyon linac (Varian Medical Systems, Palo Alto, CA, version 2.0) is designed for image‐guided radiation therapy (IGRT). The treatment unit is equipped with a double stack multi‐leaf collimator (SX2 MLC) with individual leaf widths of 1.0 cm when projected at isocenter. Both layers, which possess a relative offset of 0.5 cm, can independently contribute to beam modulation. The preconfigured system supports only a single flattening‐filter‐free (FFF) beam at nominal beam energy of 6MV. For fluence measurement the Halcyon linac is equipped with a light sensitive a‐Si photodiode based EPID (aS1200, Varian Medical Systems, Palo Alto, CA). Its active area covers 43 × 43 cm2 with a 154 cm source‐to‐imager distance (SID) and a 1280 × 1280 pixel matrix, translating into an imaging area of 28 × 28 cm² and a resolution of about 45 pixels/cm at isoplane.
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4

MLC Performance Evaluation on Linear Accelerators

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Tests were performed on 11 Varian linear accelerators (7 C‐series, 3 TrueBeam, and 1 TrueBeam‐Edge) at 5 photon clinical sites: 1 university clinic with 4 linacs, 3 community sites with 2 linacs, and 1 community site with 1 linac at the time of data acquisition. Among the 11 linacs, 3 were installed during the period of data collection, 1 was decommissioned, and 1 was taken over by another hospital system. Two MLC systems were tested: HD120, with leaf sizes of 2.5 and 5 mm; and Millennium 120, with leaf sizes of 5 and 10 mm. A 100‐cm source–imager distance (SID) was chosen based on the largest MLC field size. For each test, the collimator was rotated to 90° to align the longer dimension of the portal imager along the MLC bank. Although these MLC patterns can be collected by either films or an EPID imager, all images in this study were collected using Varian EPID aS1000 and aS1200 imager models. The aS1000 has a resolution of 1024 × 768 pixels and an active area of 40.1 × 30.1 cm2 (equivalent to 0.392‐mm pixel size).22 The aS1200 has a resolution of 1280 × 1280 pixels and an active area of 43.1 × 43.1 cm2 (equivalent to 0.336‐mm pixel size).23
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