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Ge discovery 690 pet ct scanner

Manufactured by GE Healthcare
Sourced in United States

The GE Discovery 690 PET/CT scanner is a diagnostic imaging device that combines Positron Emission Tomography (PET) and Computed Tomography (CT) technologies. It is designed to capture high-quality images of the body's internal structures and functions.

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5 protocols using ge discovery 690 pet ct scanner

1

PSMA-PET Imaging for Radiation Planning

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Prior to radiation treatment, all patients underwent a PSMA-PET (68Ga-PSMA-11) examination with low-dose CT. One hour after the injection of 2.5 MBq/kg bodyweight, with a maximum of 300 MBq, patients were scanned from the mid-thigh level to the base of the skull using a GE Discovery 690 PET-CT scanner (GE HealthCare, Milwaukee, WI, USA). The scan was analysed by two experienced readers, one a specialist in nuclear medicine and the other an oncologist, blinded to the PSA response. Uptakes not typical of a normal physiological pattern or unspecific uptake patterns were regarded as suspicious for malignancy. The treatment planning CT was available for correlation in the reading situation.
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2

Retrospective Prostate Cancer PET/CT Analysis

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We retrospectively investigated 49 prostate cancer patients with a
median age of 66 (range 46–81). Each patient was scanned by a GE
Discovery 690 PET/CT scanner (GE healthcare, Waukesha, WI). Institutional review
board approval was obtained; informed consent was not required for this Health
Insurance Portability and Accountability Act (HIPPA)-compliant retrospective
analysis. For each patient, the CT image volume has size of 512 × 512
with a number of slices around 250. The voxel size of CT is 1.37 × 1.37
× 3.75 mm. PET image volume has size of 192 × 192 with the same
number of slices as CT. The voxel size of PET is 3.65 × 3.65 ×
3.75 mm. The prostates and DILs of all 49 patients were manually contoured by a
radiologist and then reviewed and modified by a second radiologist. Each patient
had one to three DILs. The consensus contours were used as the ground truth
contours.
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3

Aortic Aneurysm PET-CT Imaging Protocol

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Patients with AAA were recruited from Cambridge University Hospitals, UK. The inclusion criteria were: age >50 years and presence of an aneurysm between 3.0 and 5.5 cm. Exclusion criteria were: insulin dependent diabetes, type 2 diabetes with a fasting glucose of >11 mmol/L, any disease expected to shorten life expectancy to <2 years, women of childbearing age not taking contraception, severe renal failure (serum creatinine >250 µmol/L), known contrast allergy or the inability to provide informed consent. All subjects provided written informed consent in accordance with the research protocol approved by the local institutional review board (IRB; MREC 09/H0308/27). All patients underwent 18F-FDG PET-CT imaging of the aorta using a GE Discovery 690 PET/CT scanner (GE Healthcare, USA). The details of imaging protocol are provided in Supplementary Material.
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4

Whole-Body PET/CT Imaging Protocol

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Whole-body PET/CT images were acquired on a Biograph mCT Flow 20-4R PET/CT scanner (Siemens, Healthcare GmbH, Erlangen, Germany) and a GE Discovery 690 PET/CT scanner (General Electric, Munich, Germany) as previously reported [22 (link),23 (link),24 (link)]. Patients fasted at least 4 h prior to administration of approximately 250 MBq 2-deoxy-2-[18F]fluoro-D-glucose (2-[18F]FDG), and emission scan acquisition of the immobilized head and neck, thorax, abdomen, and pelvis started approximately 60 min after intravenous tracer administration. Unless contraindicated, iodine-containing contrast medium (Ultravist 300, Bayer Vital GmbH, Leverkusen, Germany or Imeron 350, 2.5 mL/s, Bracco Imaging Deutschland GmbH, Konstanz, Germany) was administered for diagnostic computed tomography (CT) imaging (100–190 mAs, 120 kV; portal venous phase).
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5

Assessing Aortic Aneurysm Risk with 18F-FDG PET-CT

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Patients with AAA were recruited from Cambridge University Hospitals, United Kingdom. The inclusion criteria were age >50 years and presence of an aneurysm between 3.0 and 5.5 cm. Exclusion criteria were insulin-dependent diabetes mellitus, type 2 diabetes mellitus with a fasting glucose of >11 mmol/L, any disease expected to shorten life expectancy to <2 years, women of childbearing age not taking contraception, severe renal failure (serum creatinine >250 µmol/L), known contrast allergy, or the inability to provide informed consent. All subjects provided written informed consent in accordance with the research protocol approved by the local institutional review board (MREC 09/H0308/27). All patients underwent 18F-FDG PET-computed tomography (CT) imaging of the aorta using a GE Discovery 690 PET/CT scanner (GE Healthcare). The details of imaging protocol are provided in Material in the Data Supplement.
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