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Salicylic acid

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Salicylic acid is a white crystalline compound commonly used as a laboratory reagent. It has the chemical formula C6H4(OH)COOH and is a carboxylic acid derived from the metabolism of salicin. Salicylic acid is a widely used chemical in various scientific and industrial applications.

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Lab products found in correlation

Ethanol, by Sinopharm (2 mentions) Tetracycline, by Maclin Biochemical Technology (2 mentions) Norfloxacin, by Maclin Biochemical Technology (2 mentions) Penicillin sodium, by Maclin Biochemical Technology (2 mentions) Diuron, by Maclin Biochemical Technology (2 mentions) Disulfiram, by Maclin Biochemical Technology (2 mentions) N n dimethylformamide (dmf), by Sinopharm (2 mentions) Hydrochloric acid (hcl), by Sinopharm (2 mentions) Acetone, by Sinopharm (2 mentions) Methanol, by Sinopharm (2 mentions) Co no3 2, by Sinopharm (2 mentions) Ti no3 4, by Sinopharm (2 mentions) Tetrahydrofuran, by Sinopharm (2 mentions) Nitric acid, by Sinopharm (2 mentions) Nano3, by Sinopharm (2 mentions) Ca no3 2, by Sinopharm (2 mentions) Zn no3 2, by Sinopharm (2 mentions) Fe no3 3, by Sinopharm (2 mentions) Trichloroacetic acid, by Maclin Biochemical Technology (2 mentions) Ferrous sulfate, by Maclin Biochemical Technology (2 mentions)

10 protocols using salicylic acid

1

Synthesis and Characterization of H4TCPB

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1,2,4,5-Tetrakis (4-carboxyphenyl) benzene (H4TCPB, 98%) was supplied by Jilin Chinese Academy of Science-Yanshen Technology Co., Ltd (Changchun, China). Hydrochloric acid (HCl, 36-38%) was purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai China) N, N-dimethylformamide (DMF, 99.5%), ethanol (99.7%), methanol (99.5%), acetone (99.5%), tetrahydrofuran (99.5%) nitric acid (HNO3, 65%), NaNO3 (99%), KNO3 (99%), Ca(NO3)2 (99%), Ti(NO3)4 (99%), Zn(NO3)2 (99%), Co(NO3)2, (99%), and Fe(NO3)3 (99%) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai China) A wide range of antibiotics and chemicals, i.e., tetracycline, penicillin sodium, salicylic acid, diuron, disulfiram, and norfloxacin, were purchased from Shanghai Maclin Biochemical Technology Co., Ltd. (Shanghai China).
Zhang X., Liu W., Yang M, & Li Z. (2023). The Fabrication and Mechanism of a Crystalline Organic Fluorescent Probe Based on Photoinduced Electron Transfer. Molecules, 28(19), 6774.
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2

Synthesis and Characterization of H4TCPB

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1,2,4,5-Tetrakis (4-carboxyphenyl) benzene (H4TCPB, 98%) was supplied by Jilin Chinese Academy of Science-Yanshen Technology Co., Ltd (Changchun, China). Hydrochloric acid (HCl, 36-38%) was purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai China) N, N-dimethylformamide (DMF, 99.5%), ethanol (99.7%), methanol (99.5%), acetone (99.5%), tetrahydrofuran (99.5%) nitric acid (HNO3, 65%), NaNO3 (99%), KNO3 (99%), Ca(NO3)2 (99%), Ti(NO3)4 (99%), Zn(NO3)2 (99%), Co(NO3)2, (99%), and Fe(NO3)3 (99%) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai China) A wide range of antibiotics and chemicals, i.e., tetracycline, penicillin sodium, salicylic acid, diuron, disulfiram, and norfloxacin, were purchased from Shanghai Maclin Biochemical Technology Co., Ltd. (Shanghai China).
Zhang X., Liu W., Yang M, & Li Z. (2023). The Fabrication and Mechanism of a Crystalline Organic Fluorescent Probe Based on Photoinduced Electron Transfer. Molecules, 28(19), 6774.
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3

Extraction and Characterization of Bioactive Compounds from Chrysanthemum Flowers

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Methanol and formic acid of chromatographic grade were purchased from Beijing Mreda technology Co., Ltd. (Beijing, China). The reference standards including L-7G, 3,5-DCQA, 4,5-O-dicaffeoylquinic acid (4,5-DCQA), apigenin-7-O-glucuronide (A-7G), and kaempferol-3-O-rutinoside (K-3R) were purchased from Sichuan Weikeqi Biological Technology Co., Ltd. (Chengdu, China), while ChA was purchased from Chengdu Purechem-standard Biological Technology Co., Ltd. (Chengdu, China). Their purities were all not less than 98%. Potassium persulfate, salicylic acid, 1,1-Diphenyl-2-picrylhydrazyl (DPPH), and 2,2′-biazo-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) of analytical grade were purchased from Shanghai Maclean Biochemical Technology Co., Ltd. (Shanghai, China), while ferrous sulfate heptahydrate was purchased from Shanghai Aladdin Biochemical Technology Co., Ltd. (Shanghai, China). Other reagents were of analytical grade and water was purified using a Milli-Q system (Millipore, Bedford, MA, United States).
A total of 30 flower head samples of CMs were collected and identified by Associate Professor Shuai Ji of our laboratory as the dried flower heads of Chrysanthemum morifolium (Ramat.) Hemsl. The information of the samples was shown in Table 1.
Lu Y.F., Li D.X., Zhang R., Zhao L.L., Qiu Z., Du Y., Ji S, & Tang D.Q. (2022). Chemical Antioxidant Quality Markers of Chrysanthemum morifolium Using a Spectrum-Effect Approach. Frontiers in Pharmacology, 13, 809482.
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4

Antioxidant Capacity Evaluation Protocol

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Folin-Ciocalteu reagent, gallic acid, rutin, 2,6-ditert-butyl-4-methylphenol (BHT), 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH), 2,2-diazo-bis (3-ethyl-benzothiazole-6-sulfonic acid) diammonium salt (ABTS), tripyridyltriazine (TPTZ), isopropyl myristate (IPM), Span80, Tween 80, salicylic acid, trichloroacetic acid, ferric chloride, ferrous sulfate heptahydrate, potassium peroxodisulfate, potassium ferricyanide, etc. were all purchased In Shanghai Maclean Biochemical Technology Co., Ltd. Superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), glutathione reductase (GR) and MDA content kits were purchased from Beijing Soleibao Technology Co., Ltd. All reagents used in this study either analytical or chemical grade were commercially available.
Wang L., Ahmad S., Wang X., Li H, & Luo Y. (2021). Comparison of Antioxidant and Antibacterial Activities of Camellia Oil From Hainan With Camellia Oil From Guangxi, Olive Oil, and Peanut Oil. Frontiers in Nutrition, 8, 667744.
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5

Comprehensive Degradation Assay for Polycyclic Aromatic Hydrocarbons

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PAHs and heterocyclic compounds (PHE, NAP, ACE, FLN, ANT, FLU, BaA, PYE, CHR, DBT, DBF, CA, and indole) used for the degradation assay were purchased from Aladdin or J&K Scientific. Standards of metabolic intermediates, such as 1‐hydroxy‐2‐naphthoic acid, salicylic acid, 9‐fluorenol, 9‐fluorenone, indigo, and dibenzothiophene‐S‐oxide, were purchased from either Macklin or Sinopharm Chemical Reagent Co., Ltd. All water‐insoluble substrates were dissolved in N,N‐dimethylformamide (DMF) as stock solutions and the appropriate volume was added to the medium before use. BSTFA for derivatization of samples was purchased from Sigma‐Aldrich. The purity of all chemicals exceeded 99%. The PHE degraders were cultured with an MSM with PHE as the sole carbon source. MSM per liter consists of 3.7 g KH2PO4, 5.2 g K2HPO4·3H2O, 2.0 g NH4Cl, 1.0 g Na2SO4, 0.1 g MgSO4, and 1 ml trace metal solution
44 (link). Luria–Bertani (LB) broth medium (tryptone 1%, yeast extract 0.5%, and NaCl 1%) was used for the cultivation of E. coli and was supplemented with antibiotics when necessary. All abbreviations in the text are listed in Table S4.
Zhang L., Liu H., Dai J., Xu P, & Tang H. (2022). Unveiling degradation mechanism of PAHs by a Sphingobium strain from a microbial consortium. mLife, 1(3), 287-302.
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6

Antimicrobial Activity Screening Protocol

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Hesperetic acid, 2-hydroxybenzene-1,4-dicarboxylic acid (2-HTPA), thymol, carvacrol, eugenol, cinnamaldehyde, salicylic acid, trans-cinnamic acid, and trans-ferulic acid, as well as ethanol were purchased from Shanghai Macklin Biochemical Co., Ltd. Tween 80 was supplied by Beijing Solarbio Science & Technology Co., Ltd. LB broth was purchased from Beijing Aoboxing Bio-tech Co., Ltd. S. aureus 186335 was obtained from Beijing Beina Chuanglian Biotechnology Institute. Bacillus subtilis CMCC63501 (B. subtilis), Pseudomonas aeruginosa ATCC27853 (P. aeruginosa), and Escherichia coli ATCC25922 (E. coli) were purchased from Beijing Solarbio Science & Technology Co., Ltd.
Wang Z., Pan F., Zhang M., Liang S, & Tian W. (2024). Discovery of potential anti- Staphylococcus aureus natural products and their mechanistic studies using machine learning and molecular dynamic simulations. Heliyon, 10(9), e30389.
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7

Extraction and Analysis of Dandelion Bioactives

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Dandelion powder (3000 mesh) of the whole grass plant (Hebei, China), purchased from a local pharmacy (Taian, Shandong), stored in sealed light-resistant packaging at − 20 °C before use. The ethanol and formic acid used for HPLC-MS analysis were of chromatographic grade and obtained from Tianjin KaiTong Chemical Reagent Co., LTD (Tianjin, China). Diphenyl-1-picrylhydrazyl (DPPH), Diammonium 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonate) (ABTS), salicylic acid, and ferrous sulfate were of analytical grade and purchased from Shanghai Macklin Biochemical Co., LTD (Shanghai, China). Amberlite XAD-7HP macroporous resin was obtained from Shanghai Aladdin Bio-Chem Technology Co., Ltd. (Shanghai, China).
Wu P., Ben T., Zou H, & Chen Y. (2022). PARAFAC modeling of dandelion phenolic compound fluorescence relation to antioxidant properties. Journal of Food Measurement and Characterization, 16(4), 2811-2819.
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8

Antioxidant Capacity of Pullulan-Based Composites

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Bovine serum albumin (BSA), epigallocatechin gallate (EGCG), anhydrous ferric chloride, potassium ferricyanide, ferrous ammonium sulfate hexahydrate, salicylic acid, trichloroacetic acid, 1,1-diphenyl-2-Picrylhydrazine (DPPH), and 2,2′-Diaza-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) were obtained from Shanghai Macklin Biochemical Co., Ltd. (Shanghai, China). Pullulan (PUL) was purchased from Shanghai Yien Chemical Technology Co., Ltd. (Shanghai, China). Hydrogen peroxide (purity ≥ 30%), potassium dihydrogen phosphate, dipotassium hydrogen phosphate, absolute ethanol, hydrochloric acid, and sodium hydroxide were purchased from China National Medicines Corporation Ltd. (Shanghai, China).
Li Z., Wang X., Zhang M., He H., Liang B., Sun C., Li X, & Ji C. (2022). The Loading of Epigallocatechin Gallate on Bovine Serum Albumin and Pullulan-Based Nanoparticles as Effective Antioxidant. Foods, 11(24), 4074.
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9

Synthesis of Zinc-Based Catalysts

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Zinc nitrate hexahydrate [Zn(NO3)2·6H2O] (99%, AR), melamine (99%, AR), polyvinylpyrrolidone K30 (GR), N-hexane (AR), Dichloromethane (AR), sodium borohydride (>98%), anhydrous ethanol (99.7%, AR), sodium hydroxide (>96%, AR), isopropyl alcohol (99.7%, AR), and toluene (99.5%, AR) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Salicylic acid (99.5%, AR), glutaric dialdehyde (AR), and CALB (immobilized lipase B from Candida Antarctica) were purchased from Macklin Biochemical Co., Ltd. (Shanghai, China). Span 85 (AR), Palladium(II) acetylacetonate (99%), rac-1-Phenylethylamine (99%), and (S)-1-Phenethylamine (>98%) were purchased from Aladdin Bio-Chem Technology Co., Ltd. (Shanghai, China). Imidazole-2-carbaldehyde (>95%) was purchased from Bide Pharmatech Ltd. (Shanghai, China). The 4-Chlorophenyl pentanoate was obtained via chemical organic synthesis. Hydrogen (>99.99%) was obtained from Hangzhou Minxing Chemical Technology Co., Ltd. (Hangzhou, China).
Li P., Zhu J., Zhang H., Wang L., Wang S., Zhang M., Wu J., Yang L, & Xu G. (2023). Preparation of Coupling Catalyst HamZIF-90@Pd@CALB with Tunable Hollow Structure for Efficient Dynamic Kinetic Resolution of 1-Phenylethylamine. Molecules, 28(3), 922.
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10

Synthesis of Silver Nanoparticles

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Silver nitrate (AgNO3) was purchased from Beijing TanMo Quality Testing Technology (China); l-glutathione reduced (GSH, ≥ 97%), sodium borohydride (NaBH4, ≥ 97%), and sodium hydroxide (NaOH, ≥ 97%) were purchased from Tianjin heowns Biochemical Technology (China); Salicylic acid (C7H6O3, ≥ 99.5%) and ferrous sulfate (FeSO4, ≥ 98%) were purchased from Shanghai Macklin Biochemical (China); Ultrapure Millipore water (H2O, 18.2 MΩ) was used in the whole study.
Guo J., Yang H., Liu Y., Liu W., Zhao R., Li H., Long W., Xu W., Guo M, & Zhang X. (2021). Atomically precise silver clusterzymes protect mice from radiation damages. Journal of Nanobiotechnology, 19, 377.
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