PD-L1 aptamer was modified with a 5′ polyT spacer and 5′thiol. The DNA of SH-TTTTTTTTTT-ACGGGCCACATCAACTCATTGATAGACAATGCGTCCACTGCCCGT was synthesized by Invitrogen (Shanghai, China). Fexofenadine was purchased from Tokyo Chemical Industry Co., Ltd. (Shanghai, China). Bovine serum albumin (BSA) was purchased from TBD Science Bio-engineering Co., Ltd. (Tianjin, China). Tris (2-carboxyethyl) phosphine (TCEP) and coumarin 6 were purchased from Sigma-Aldrich (Shanghai, China). Sulfosuccinimidyl 4-[N-maleimidomethyl]cyclohexane-1-carboxylate (Sulfo-SMCC) was purchased from Jinsui Bio-Technology Co., Ltd. (Shanghai, China).
Fexofenadine
Manufactured by Tokyo Chemical Industry
Sourced in Japan
Fexofenadine is a laboratory equipment product produced by Tokyo Chemical Industry. It is a chemical compound used in various research and development applications.
Automatically generated - may contain errors
Lab products found in correlation
Ofloxacin, by MedChemExpress (2 mentions)
Lamotrigine, by MedChemExpress (2 mentions)
Digoxin, by MedChemExpress (2 mentions)
Atenolol, by MedChemExpress (2 mentions)
Carbamazepine, by MedChemExpress (2 mentions)
Propranolol, by MedChemExpress (2 mentions)
Diltiazem, by MedChemExpress (2 mentions)
Quinidine, by MedChemExpress (2 mentions)
Antipyrine, by MedChemExpress (2 mentions)
Coumarin 6, by Merck Group (1 mentions)
Tris 2 carboxyethyl phosphine tcep, by Merck Group (1 mentions)
Memantine, by MedChemExpress (1 mentions)
Gabapentin, by MedChemExpress (1 mentions)
Acetaminophen, by Merck Group (1 mentions)
Pemetrexed, by MedChemExpress (1 mentions)
Citalopram, by MedChemExpress (1 mentions)
Sumatriptan, by Tokyo Chemical Industry (1 mentions)
Ganciclovir, by MedChemExpress (1 mentions)
Loratadine, by Tokyo Chemical Industry (1 mentions)
Pranlukast, by Cayman Chemical (1 mentions)
4 protocols using fexofenadine
1
Functionalized PD-L1 Aptamer Synthesis
2
Comparative Physicochemical Characterization
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In this study, 14 compounds with different physiochemical properties were selected. Antipyrine, ofloxacin, lamotrigine, digoxin, quinidine, atenolol, carbamazepine, propranolol, diltiazem, memantine, diphenhydramine, pyrilamine, and gabapentin were purchased from MedChemExpress (Monmouth Junction). Fexofenadine was purchased from Tokyo Chemical Industry. The other chemicals and reagents were of the HPLC grade or better.
3
Physicochemical Characterization of Diverse Compounds
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In all, 18 compounds with different physiochemical properties were selected for this study. Antipyrine, ganciclovir, ofloxacin, 4‐aminoAntipyrine, lamotrigine, theophylline, citalopram, digoxin, quinidine, pemetrexed, atenolol, carbamazepine, propranolol, and diltiazem were purchased from MedChemExpress (Monmouth Junction). Acetaminophen was purchased from Sigma‐Aldrich. Fexofenadine and sumatriptan were purchased from Tokyo Chemical Industry. Cimetidine was purchased from National Institute for the Control of Pharmaceutical and Biological Products. All the other chemicals were of the HPLC grade or better.
4
Diverse Pharmacological Modulators of Inflammatory Pathways
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Montelukast, pranlukast and zafirlukast as leukotriene receptor antagonists were purchased from Cayman Chemical (Ann Arbor, MI, USA). Suplatast tosilate as a Th2 cytokine inhibitor, sodium cromoglicate, tranilast, amlexanox and pemirolast as mediator release inhibitors, ozagrel as a thromboxane A2 synthesis inhibitor, seratrodast as a thromboxane A 2 receptor antagonist, diphenhydramine as an ethanolamine H1 blocker, chlorpheniramine as a propylamine H1 blocker, cyproheptadine as a piperidine H1 blocker, promethazine as a phenothiazine H1 blocker, and ketotifen, fexofenadine, epinastine, cetirizine, levocetirizine, emedastine, loratadine, azelastine, mequitazine and ebastine as second-generation H1 receptor antagonists were purchased from Tokyo Chemical Industry (Tokyo, Japan).
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