Phosphotungstic acid

Manufactured by Maclin Biochemical Technology

Sourced in China

Phosphotungstic acid is a chemical compound with the formula H3PW12O40. It is a white crystalline solid that is used as a reagent in various analytical and chemical applications. The primary function of phosphotungstic acid is to serve as a precipitating agent for certain proteins and other organic compounds.

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Lab products found in correlation

Pyrene, by Maclin Biochemical Technology (1 mentions) Glutaraldehyde, by Maclin Biochemical Technology (1 mentions) Docetaxel, by Merck Group (1 mentions) Polysorbate 80, by Maclin Biochemical Technology (1 mentions) Anti β tubulin antibody, by BioLegend (1 mentions) Fitc gelatin, by AnaSpec (1 mentions) Fitc anti mouse cd44, by BioLegend (1 mentions) 3 maleimidopropionic acid, by Merck Group (1 mentions) Cell counting kit 8 cck 8, by Dojindo Laboratories (1 mentions) 4 6 diamidino 2 phenylindole (dapi), by Solarbio (1 mentions) Hoechst 33342, by Solarbio (1 mentions) Fetal bovine serum (fbs), by Wisent (1 mentions) Rpmi 1640 medium, by Wisent (1 mentions) Triethylamine tea, by Maclin Biochemical Technology (1 mentions) Sodium hydroxide (naoh), by Merck Group (1 mentions) Hydrochloric acid (hcl), by Merck Group (1 mentions) Tetrahydrofuran thf, by Shanghai Titan Scientific (1 mentions) Acetonitrile, by Shanghai Titan Scientific (1 mentions) Triethylamine, by Maclin Biochemical Technology (1 mentions) Tetrahydrofuran, by Maclin Biochemical Technology (1 mentions)

3 protocols using phosphotungstic acid

Docetaxel-Based Tumor-Targeted Nanoparticles

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Docetaxel, 3-maleimidopropionic acid, 4-(dimethylamino) pyridine (DMAP), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDCI) were obtained from Sigma–Aldrich (Burlington, MA, USA). Deuterium chloride, dimethyl sulfoxide (DMSO) and dichloromethane (DCM) were purchased from Innochem (Beijing, China). Cy5.5 dye, pyrene, glutaraldehyde, polysorbate 80 and phosphotungstic acid were provided by Macklin (Shanghai, China). APC anti-mouse CD133, FITC anti-mouse CD44, anti-β-tubulin antibody were purchased from Biolegend (San Diego, CA, USA). Hoechst 33,342 and DAPI were purchased from Solarbio (Beijing, China). TRITC-phalloidin was provided by Lablead (Beijing, China). Cell counting kit-8 (CCK-8) was provided by Dojindo Laboratories (Kumamoto, Japan). FITC-gelatin was purchased from AnaSpec (Fremont, CA, USA). RPMI-1640 medium and FBS were acquired from Wisent (Nanjing, China).

Li C., Lang J., Wang Y., Cheng Z., Zu M., Li F., Sun J., Deng Y., Ji T., Nie G, & Zhao Y. (2023). Self-assembly of CXCR4 antagonist peptide–docetaxel conjugates for breast tumor multi-organ metastasis inhibition. Acta Pharmaceutica Sinica. B, 13(9), 3849-3861.

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Avermectin-loaded EMA Nanoparticle Synthesis

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Ethylene–maleic anhydride copolymer (EMA, prepared in our lab according to reference [60 (link)] number average molecular weight (M_n) is 5978 g/moL, weight average molecular weight (M_w) is 10,913 g/moL, polydispersity index (PDI) is 1.826), avermectin (Avm, MYM Biological Technology Company, Telangana, IN, USA, 95%), avermectin emulsifiable concentrate (Avm-EC, Chinese Academy of Agricultural Sciences, Beijing, China, 5%), Nile red (Shanghai Bide Pharmatech Co., Ltd., Shanghai, China, 98%), dialysis bag (MD3500, Spectrumlabs, San Francisco, CA, USA). Tetrahydrofuran (THF), dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), acetonitrile, N-methyl-2-pyrrolidinone (NMP), and 1,3-dimethyl-3,4,5,6-tetrahydro-2(¹H)-pyrimidinone (DMPU) were purchased from Shanghai Titan Scientific Co., Ltd., Shanghai, China, AR. Hydrochloric acid (0.0998 mol/L) and sodium hydroxide (NaOH, 0.0998 mol/L) were purchased from Sigma–Aldrich, St. Louis, MO, USA, AR. Triethylamine (TEA) and phosphotungstic acid were purchased from Shanghai Macklin Biochemical Co., Ltd., Shanghai, China, AR.

Cheng Y., Pan Z., Tang L., Huang Y, & Yang W. (2024). Fabrication of Eco-Friendly Hydrolyzed Ethylene–Maleic Anhydride Copolymer–Avermectin Nanoemulsion with High Stability, Adhesion Property, pH, and Temperature-Responsive Releasing Behaviors. Molecules, 29(5), 1148.

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Synthesis of PEGylated Bedaquiline Derivatives

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Methoxypolyethylene glycol-OH (mPEG, MW2000); α-bromoisobutyryl bromide (EBiB, 98%, 195.05 g mol^–1); 2,2-dipyridyl (bPy, 99%, 156.19 g mol^–1); cuprous bromide (CuBr, 99%, 143.15 g mol^–1); N,N,N′,N′,N′-pentamethyldiethylenetriamine (PMDETA, 173.3 g mol^–1); dichloromethane (DCM); triethylamine; tetrahydrofuran (THF); and phosphotungstic acid were purchased from Macklin (Shanghai, China). 2-(Diisopropylamino) ethyl methacrylate (DPA) was purchased from Sigma-Aldrich (Merck KGaA, German). Bedaquiline was purchased from MedChemExpress (United States).

Zhang M., Yu Z, & Lo E.C. (2021). A New pH-Responsive Nano Micelle for Enhancing the Effect of a Hydrophobic Bactericidal Agent on Mature Streptococcus mutans Biofilm. Frontiers in Microbiology, 12, 761583.

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