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Type 7650

Manufactured by Ugo Basile
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Sourced in Italy

The Type 7650 is a laboratory equipment product manufactured by Ugo Basile. It serves as a core function for the intended application, but a detailed description cannot be provided while maintaining an unbiased and factual approach without extrapolation.

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Lab products found in correlation

6 protocols using type 7650

1

Rotarod Test for Motor Coordination

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The rotarod test was performed at seven, fifteen and twenty-four weeks of age to evaluate coordination and motor skill acquisition (Type 7650; Ugo Basile). The mice were placed on the rotating rod (3 cm diameter, 30 cm long) for 4 trials every day for a period of 4 days. Each trial lasted a maximum of 10 min. The rod accelerated from 4 to 40 rpm in 5 min, and remained at 40 rpm for the remaining 5 min. The time the mice took to fall was recorded. Two subsequent rotations around the rod were also counted as a fall.
Coffin S.L., Durham M.A., Nitschke L., Xhako E., Brown A.M., Revelli J.P., Gonzalez E.V., Lin T., Handler H.P., Dai Y., Trostle A.J., Wan Y.W., Liu Z., Sillitoe R.V., Orr H.T, & Zoghbi H.Y. (2022). Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron, 111(4), 481-492.e8.
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2

Rotarod Test for Motor Coordination

Check if the same lab product or an alternative is used in the 5 most similar protocols
The rotarod test was performed at seven, fifteen and twenty-four weeks of age to evaluate coordination and motor skill acquisition (Type 7650; Ugo Basile). The mice were placed on the rotating rod (3 cm diameter, 30 cm long) for 4 trials every day for a period of 4 days. Each trial lasted a maximum of 10 min. The rod accelerated from 4 to 40 rpm in 5 min, and remained at 40 rpm for the remaining 5 min. The time the mice took to fall was recorded. Two subsequent rotations around the rod were also counted as a fall.
Coffin S.L., Durham M.A., Nitschke L., Xhako E., Brown A.M., Revelli J.P., Gonzalez E.V., Lin T., Handler H.P., Dai Y., Trostle A.J., Wan Y.W., Liu Z., Sillitoe R.V., Orr H.T, & Zoghbi H.Y. (2022). Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron, 111(4), 481-492.e8.
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3

Rotarod Test for Motor Coordination

Check if the same lab product or an alternative is used in the 5 most similar protocols
The rotarod test was performed at 7 and 24 weeks of age to evaluate coordination and motor skill acquisition (type 7650; Ugo Basile). The mice were placed on the rotating rod (3 cm diameter, 30 cm long) for 4 trials every day for a period of 4 days. Each trial lasted a maximum of 10 minutes. The rod accelerated from 4 to 40 rpm in 5 minutes and remained at 40 rpm for the remaining 5 minutes. The time the mice took to fall was recorded. Two subsequent rotations around the rod were also counted as a fall.
Nitschke L., Coffin S.L., Xhako E., El-Najjar D.B., Orengo J.P., Alcala E., Dai Y., Wan Y.W., Liu Z., Orr H.T, & Zoghbi H.Y. (2021). Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1. JCI Insight, 6(3), e144955.
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4

Rotarod Test for Motor Coordination

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The rotarod test was performed at 10 wk of age to evaluate coordination and motor skill acquisition (type 7650; Ugo Basile). For each test, the mice were habituated for 30 min in the test room before testing. The mice were placed on the rotating rod (3-cm diameter, 30 cm long) for four trials every day for a period of 4 d. Each trial lasted a maximum of 10 min. The rod accelerated from 4 to 40 rpm in 5 min, and remained at 40 rpm for the remaining 5 min. The time the mice took to fall was recorded. Two subsequent rotations around the rod were also counted as a fall.
Nitschke L., Tewari A., Coffin S.L., Xhako E., Pang K., Gennarino V.A., Johnson J.L., Blanco F.A., Liu Z, & Zoghbi H.Y. (2020). miR760 regulates ATXN1 levels via interaction with its 5′ untranslated region. Genes & Development, 34(17-18), 1147-1160.
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5

Accelerated Rotating Rod Test

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Coordination and motor function were measured by using an accelerated rotating rod test (type 7650; Ugo Basile, Milan, Italy). Mice were placed on the rod (3 cm diameter, 30 cm long) for four trials, with each trial lasting 5 minutes. The rod accelerated from 4 to 40 rpm in 5 min. Latency to fall for each mouse was recorded.
Comerota M., Gedam M., Xiong W., Jin F., Deng L., Wang M., Wang J, & Zheng H. (2023). Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates Ab pathology in a mouse model of Alzheimer’s disease. Research Square.
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6

Rotarod Test for Motor Coordination

Check if the same lab product or an alternative is used in the 5 most similar protocols
The rotarod test was performed at 7 or 11 weeks of age to evaluate coordination and motor skill acquisition (type 7650; Ugo Basile). The mice were placed on the rotating rod (3 cm diameter, 30 cm long) for 4 trials every day for a period of 4 days. Each trial lasted a maximum of 10 minutes. The rod accelerated from 4 to 40 rpm in 5 minutes and remained at 40 rpm for the remaining 5 minutes. The amount of time it took for the mice to fall was recorded. Two subsequent rotations around the rod were also counted as a fall.
Orengo J.P., Nitschke L., van der Heijden M.E., Ciaburri N.A., Orr H.T, & Zoghbi H.Y. (2022). Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model. JCI Insight, 7(8), e154442.
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