1.5t system

Manufactured by GE Healthcare

Sourced in United States

The 1.5T system is a magnetic resonance imaging (MRI) device designed for clinical use. It operates at a magnetic field strength of 1.5 Tesla, which is a common field strength for MRI scanners. The core function of the 1.5T system is to generate high-quality images of the human body for diagnostic purposes.

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Lab products found in correlation

Molybdenum target radiographic image unit, by GE Healthcare (4 mentions) 3t scanner, by Philips (2 mentions) 3t system, by Philips (2 mentions) Magnetom verio, by Siemens (1 mentions) Magnevist, by Bayer (1 mentions) 3t magnetic resonance scanner, by Philips (1 mentions) Ge 1.5t, by Philips (1 mentions) Gyroscan intera 1.5t, by Philips (1 mentions) 3t intera, by Philips (1 mentions) Somaton definition as, by Siemens (1 mentions)

24 protocols using 1.5t system

Healthy Brain MRI Dataset

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This dataset comprises images from normal, healthy participants, along with demographic characteristics, collected as part of the IXI project available for download (https://brain-development.org/ixi-dataset/). The data have been collected at three hospitals in London (Hammersmith Hospital using a Philips 3T system, Guy’s Hospital using a Philips 1.5T system, and Institute of Psychiatry using a GE 1.5T system). Inclusion criteria for the present study were availability of completed baseline MRI data.

Hahn T., Ernsting J., Winter N.R., Holstein V., Leenings R., Beisemann M., Fisch L., Sarink K., Emden D., Opel N., Redlich R., Repple J., Grotegerd D., Meinert S., Hirsch J.G., Niendorf T., Endemann B., Bamberg F., Kröncke T., Bülow R., Völzke H., von Stackelberg O., Sowade R.F., Umutlu L., Schmidt B., Caspers S., Kugel H., Kircher T., Risse B., Gaser C., Cole J.H., Dannlowski U, & Berger K. (2022). An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling. Science Advances, 8(1), eabg9471.

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Preoperative MRI Imaging Protocol

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Preoperative MRI was performed using a 3T scanner (Magnetom Verio; Siemens, Erlangen, Germany). The routine imaging protocol included the following sequences: sagittal T1-weighted spin-echo (TR/TE, 440ms/2.48ms), axial T2-weighted fast spin-echo (FSE) (TR/TE, 4900ms/96ms), axial T1-weighted spin-echo sequence (TR 250ms, TE 2.67ms) performed before and after intravenous administration of gadolinium-DTPA (Magnevist, Bayer-Schering), 5mm slice thickness, 1mm intersection gap. MRI data for vessel size imaging (VSI) was acquired using a 1.5T system (GE Healthcare) with following sequences: i.v. injection of Gd-DTPA using a gradient-echo spin-echo (GE-SE) sequence, with acquisition parameters: field of view = 24 × 24cm, TR 1500ms, TE (GE) 30ms, TE (SE) 100ms, flip angles = 90°, matrix size = 64 × 64, NEX 1, slice number was 7, and 50 images were obtained at each slice. As well, 0.2mmol of gadobutrol per kilogram of body weight was injected at a rate of 3mL/s and immediately followed by a 20mL bolus of saline.

Kang H., Chen P., Guo H., Zhang L., Tan Y., Xiao H., Yang A., Fang J, & Zhang W. (2020). Vessel Size Imaging is Associated with IDH Mutation and Patient Survival in Diffuse Lower-Grade Glioma. Cancer Management and Research, 12, 9801-9811.

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Radiographic and MRI Evaluation of Intervertebral Disc Height

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Seven days after the initial puncture, each group of rats was randomly selected to undergo X-ray and MRI scans before sacrifice [25 (link)]. The rats were maintained in a supine position with their tails straight for placement on a molybdenum target radiographic-image unit (GE, Boston, MA, USA). Radiographs were captured at a collimator-to-film distance of 66 cm, an exposure of 63 mAs, and a penetration power of 35 kV. We performed MRI using a 1.5 T system (GE) to obtain T2-weighted images (repetition time: 3000 ms; echo time: 80 ms; field of view: 200 mm²; slice thickness: 1.4 mm) in the coronal plane. All the radiographic images were saved in a Neusoft PACS/RIS DICOM 3.0 medical imaging system (Neusoft, Jinan, China). The IVD height and the adjacent upper and lower vertebral body heights were measured using Neusoft PACS/RIS measuring tools, and the disc height index (DHI) was calculated from these values.

Yu H., Hou G., Cao J., Yin Y., Zhao Y, & Cheng L. (2021). Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway. Oxidative Medicine and Cellular Longevity, 2021, 6632786.

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Pelvic MRI Acquisition Protocol

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All patients underwent pelvic MRIs in a 1.5-T system (GE Medical System, Milwaukee, Wisconsin) using torso coil, and the axial, coronal, and sagittal planes were included. Fast imaging using steady-state acquisition and fast inversion recovery motion insensitive were used. Their parameters were as follows: flip angle of 60° and 55°; echo time/repetition time of 1.6–1.8/3.6–3.9 ms and 2.0–5.3 ms/7.7–10.7 ms, respectively; thickness of 4 to 5 mm; slice interval of 0 to 2 mm; 224 × 224 matrix; and a field of view of 360 to 420 mm.

Chu C., Zhao S., Ding M., Liu M., Zhang Y., Bao L., Wang D, & Li W. (2019). Combining Clinical Characteristics and Specific Magnetic Resonance Imaging Features to Predict Placenta Accreta. Journal of Computer Assisted Tomography, 43(5), 775-779.

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LPBA40 Brain MRI Parcellation Protocol

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The LPBA40 dataset was used for validation of the proposed method ([18 (link)], http://www.loni.usc.edu/atlases/Atlas_Detail.php?atlas_id=12). It consists of 40 T1-weighted brain MRI data (20 males and 20 females, 29.20 ± 6.30 years). The scans were acquired with a three-dimensional spoiled gradient echo sequence on a GE 1.5 T system as 124 contiguous 1.5 mm coronal slices. The acquisition parameters were repetition time, 10.0–12.5 ms; echo time, 4.22–4.5 ms; flip angle, 20°; field of view, 220 mm or 200 mm. Experienced raters parcellated all 40 brain datasets manually into 56 structures, including the cerebellum and brain stem.

Lee D.K., Yoon U., Kwak K, & Lee J.M. (2015). Automated Segmentation of Cerebellum Using Brain Mask and Partial Volume Estimation Map. Computational and Mathematical Methods in Medicine, 2015, 167489.

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Radiographic and MRI Evaluation of Rabbit Joints

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The rabbits in each group were performed an X-ray before execution. Radiographs were captured at a collimator-to-film distance of 66 cm, an exposure of 63 mAs and a penetration power of 35 kv. MRI was performed for each group at 3, 6, 11 and 14 weeks, and T2-weighted images (repetition time: 3000 ms; echo time: 80 ms; field of view: 200 mm²; slice thickness: 1.4 mm) were obtained by MRI using a 1.5-T system (GE) in the sagittal plane. The MRI grade of NPs was evaluated as previously reported.

Yang W., Jia C., Liu L., Fu Y., Wu Y., Liu Z., Yu R., Ma X., Gong A., Liu F., Xia Y., Hou Y., Li Y, & Zhang L. (2022). Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress. Inflammation, 46(1), 270-284.

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MRI-based Brain Volumetric Analysis

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T1-weighted MRI images from each participant were generated using a General Electric 1.5 T system and applying a high-resolution antenna and a homogenization PURE filter (Fast Spoiled Gradient Echo sequence, TR/TE/TI = 11.2/4.2/450 ms; flip angle 12°; 1 mm slice thickness, 256 × 256 matrix, and FOV 25 cm). Freesurfer software (version 6.1.0) was used for automated cortical parcellation and subcortical segmentation [21 (link)]. The measures that were included in further analyses were total gray matter (GM), precuneal, and hippocampal volumes (in mm³). The volumes of bilateral structures were collapsed in order to obtain a single measure for each region.

de Frutos-Lucas J., Cuesta P., Ramírez-Toraño F., Nebreda A., Cuadrado-Soto E., Peral-Suárez Á., Lopez-Sanz D., Bruña R., Marcos-de Pedro S., Delgado-Losada M.L., López-Sobaler A.M., Concepción Rodríguez-Rojo I., Barabash A., Serrano Rodriguez J.M., Laws S.M., Dolado A.M., López-Higes R., Brown B.M, & Maestú F. (2020). Age and APOE genotype affect the relationship between objectively measured physical activity and power in the alpha band, a marker of brain disease. Alzheimer's Research & Therapy, 12, 113.

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Dynamic Contrast-Enhanced MRI Protocol

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MRI scans at each time included pre- and post-Gd-DTPA volumetric T1-weighted, T2-weighted fluid-attenuated inversion recovery (FLAIR), and 3-D volumetric DCE T1-weighted images. To eliminate the time-of-flight effect from in-flow blood proton spins, all DCE images were acquired in the sagittal plane and covered the whole brain. For the first 12 patients who were scanned on a 1.5-T system (General Electric HealthCare), the DCE images were acquired using a 3-D gradient echo sequence with a flip angle of 20°, TE/TR of 1.08/3.4 ms, a voxel size of 0.86 × 0.86 × 6 mm³ and a temporal resolution of approximately 6 seconds. Due to the system upgrade, the remaining 15 patients had scans on a 3-T scanner (Philips Healthcare), and had the DCE images acquired with TE/TR of 1.05/5.14 ms, a voxel size of 2 × 2 × 2 mm³. All patients had a single dose (0.1 mL/kg) of Gd-DTPA, injected at a rate of 2 mL/s. No patient was scanned on different scanners.

Farjam R., Pramanik P., Aryal M.P., Srinivasan A., Chapman C.H., Tsien C.I., Lawrence T.S, & Cao Y. (2015). A radiation-induced hippocampal vascular injury surrogate marker predicts late neurocognitive dysfunction. International journal of radiation oncology, biology, physics, 93(4), 908-915.

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Intervertebral Disc Height Measurement

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Seven days after the initial annulus puncture, each group of rats (n = 20) was randomly selected to undergo X-ray (n = 10) and MRI (n = 10) scans before these were sacrificed. The rats were kept in a supine position with their tails straight for placement on a molybdenum target radiographic-image unit (General Electric, Boston, MA, USA). Radiographs were taken at a collimator-to-film distance of 66 cm, an exposure of 63 mAs, and a penetration power of 35 kV. We performed MRI using a 1.5 T system (GE) to obtain T2-weighted images (repletion time: 3,000 ms; echo time: 80 ms; field of view: 200 mm²; slice thickness: 1.4 mm) on the coronal plane. All of the radiographic images were saved in a Neusoft PACS/RIS DICOM 3.0 medical imaging system (Neusoft, Liaoning, China). IVD height and the adjacent upper and lower vertebral-body heights were measured using Neusoft PACS/RIS measuring tools; from these values, the disc height index (DHI) was calculated.

Liu Y., Lin J., Wu X., Guo X., Sun H., Yu B., Shen J., Bai J., Chen Z., Yang H., Geng D, & Mao H. (2019). Aspirin-Mediated Attenuation of Intervertebral Disc Degeneration by Ameliorating Reactive Oxygen Species In Vivo and In Vitro. Oxidative Medicine and Cellular Longevity, 2019, 7189854.

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Imaging Evaluation of Annulus Puncture

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After 4, 7, 14, and 28 days of initial annulus puncture, 10 rats in each group (n = 10) were randomly chosen to undergo X-ray and MRI before they were sacrificed. These rats were kept in a supine position with their tails placed in a straight line on a molybdenum target radiographic image unit (GE Healthcare, Chicago, IL, USA). Radiographs were taken at a collimator-to-film distance of 66 cm, an exposure of 63 mAs, and a penetration power of 35 kV. MRI was performed using a 1.5T system (GE) to obtain T2-weighted images (repletion time, 3000 ms; echo time, 80 ms; field of view, 200 × 200 mm; slice thickness, 1.4 mm) in the coronal plane.

Wu X., Liu Y., Guo X., Zhou W., Wang L., Shi J., Tao Y., Zhu M., Geng D., Yang H, & Mao H. (2018). Prolactin inhibits the progression of intervertebral disc degeneration through inactivation of the NF-κB pathway in rats. Cell Death & Disease, 9(2), 98.

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