Methanol chromatographic reagent grade

Zinc nitrate hexahydrate (Zn(NO₃)₂·6H₂O) was purchased from Shanghai Aladdin Biochemical Technology Co., Ltd. (Shanghai, China). Terephthalic acid (H₂BDC) and dimethyl sulfoxide (DMSO) were obtained from Tianjin Guangfu Fine Chemical Research Institute (Tianjin, China). Triethylamine (TEA) was acquired from Tianjin Fuchen Chemical Reagent Factory (Tianjin, China). Trichloromethane (CHCl₃) and N,N-Dimethylformamide (DMF) were got from Beijing Chemical Factory (Beijing, China). ORI was purchased from Nantong Feiyu Biotechnology Co., Ltd. (Nantong, China). Methanol (Chromatographic reagent grade) was obtained from Thermo Fisher Scientific (Shanghai, China). PBS and penicillin-streptomycin mixture were purchased from Solarbio (Beijing, China). High-glucose Dulbecco’s Modified Eagle Medium (DMEM) was obtained from Corning (Manassas, VA, USA). Fetal bovine serum was available from Zhejiang Tianhang Biotechnology Co., Ltd. (Zhejiang, China). 3-(4,5-dimethylthiazol-2-yl)-2,5-dipheny-ltetrazolium bromide (MTT) was obtained from Beijing Biodee Biotechnology Co., Ltd. (Beijing, China). 4′,6-diamidino-2-phenylindole (DAPI) and Annexin V-FITC Apoptosis Detection Kit were purchased from Shanghai Beyotime Biotechnology Co., Ltd. (Shanghai, China). All chemicals were of analytical grade or higher.

Zinc nitrate hexahydrate (Zn(NO₃)₂·6H₂O) was purchased from Shanghai Aladdin Biochemical Technology Co., Ltd. (Shanghai, China); triethylamine (TEA) and 4′,4-biphthalic acid (4,4′-BPDC) were bought from the Tianjin Guangfu Fine Chemical Research Institute (Tianjin, China); N,N-dimethylformamide (DMF) and trichloromethane (CHCl₃) were obtained from the Beijing Chemical Factory (Beijing, China); methanol (chromatographic reagent grade) was obtained from Thermo Fisher Scientific (Shanghai, China); curcumin (CUR)( Figures S4–S7) was purchased from Shanghai Yuanye Bio-Technology Co., Ltd. (LOT:R12A10S85604, 98%); dimethyl sulfoxide (DMSO), high-glucose Dulbecco’s modified Eagle’s medium (DMEM), PBS, and a penicillin–streptomycin mixture were purchased from Solarbio (Beijing, China); fetal bovine serum (FBS) was acquired from Corning; 3-(4,5-dimethylthiazol-2-yl)-2,5-dipheny-ltetrazolium bromide (MTT) was acquired from Beijing BioDee Biotechnology Co., Ltd. (Beijing, China); 4′,6-diamidino-2-phenylindole (DAPI), an Annexin V-FITC Apoptosis Detection Kit, Lyso-Tracker Red Kit, ROS assay kit, and mitochondrial membrane potential assay kit with JC-1 were purchased from Shanghai Beyotime Biotechnology Co., Ltd. (Shanghai, China); HepG2 cells were purchased from Guangzhou Jeniobio Biotechnology (Beijing, China).