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2 anthranilic acid

Manufactured by Merck Group
Sourced in Germany

2-anthranilic acid is a chemical compound used as a raw material in various industrial applications. It is a white crystalline solid with a characteristic odor. 2-anthranilic acid is a precursor for the synthesis of a wide range of chemical products, including pharmaceuticals, dyes, and other specialty chemicals. Its core function is to serve as a building block for the production of more complex molecules, and it is widely used in the chemical industry.

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2 protocols using 2 anthranilic acid

1

Synthesis of Dihydro-coumaroyl and Coumaroyl Anthranilate Amides

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The chemical standard for methyl 3-hydroxy-2-(3-(4-hydroxyphenyl)propanamido)benzoate [dihydro-coumaroyl anthranilate amide (2)] and (E)-methyl 3-hydroxy-2-(3-(4-hydroxyphenyl)acrylamido)benzoate [coumaroyl anthranilate amide (3)] was purchased from Toronto Research Chemicals (Canada). Methyl 2-amino-3-hydroxybenzoate [3-HAA methyl ester (1)] was purchased from Apollo Scientific (UK). p-Coumaric acid, malonyl-CoA, 3-HAA, methyl 3-hydroxybenzoate, 2-amino-3-methoxybenzoic acid, 2-amino-4-methoxybenzoic acid, 2-amino-5-methoxybenzoic acid, 2-amino-5-hydroxybenzoic acid, and 2-anthranilic acid were purchased from Sigma-Aldrich (St. Louis, MO). Naringenin chalcone was purchased from Biosynth Carbosynth (USA). Naringenin was purchased from MedChemExpress (USA). p-coumaroyl-CoA standard was purchased from PlantMetaChem (Germany).
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2

Glycan Analysis of Monoclonal Antibodies

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Rapid PNGase F was purchased from New England BioLabs (Frankfurt am Main, Germany). Acetonitrile, 1-butanol, ethanol, acetic acid, 1-propanol, and 96-well filter plates were obtained from Merck (Darmstadt, Germany). Formic acid, 2-methylpyridine borane complex, and 2-anthranilic acid were acquired from Sigma-Aldrich (Munich, Germany); 96-well Strata SI-1 SPE plates were from Phenomenex (Aschaffenburg, Germany). Monoclonal antibodies and Fc-fusion proteins were procured from in-house development at Novartis. Reversed-phase chromatographic columns were from Phenomenex (Luna Omega 1.6 μm C18; 150 × 2.1 mm; Luna Omega Polar 1.6 μm C18; 150 × 2.1 mm) and Agilent (Zorbax RRHD Bonus RP 1.8 μm C14; 150 × 2.1 mm) and the HILIC column was purchased from Waters (ACQUITY UPLC Glycan BEH Amide 1.7 μm, 150 × 2.1 mm).
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