Vysis myc

Manufactured by Abbott

The Vysis MYC is a laboratory equipment product developed by Abbott. It is designed for the detection and analysis of the MYC gene, which is involved in cell growth and division. The Vysis MYC provides a tool for researchers and clinicians to study the genetic profile of samples.

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Lab products found in correlation

Novocastra, by Leica (2 mentions)

Close spelling variants of this product

Vysis LSI SpectrumOrange c-MYC Probe (4 citations) Vysis LSI MYC dual-color break-apart rearrangement probe (3 citations)

2 protocols using vysis myc

EBV Latency and MYC/IGH Translocations

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Epstein-Barr virus (EBV) latency was assessed by in situ hybridization using the probes (Novocastra; Leica Biosystems, Wetzler, Germany for BL and ZytoFast EBV-CISH system; ZytoVision, Bremerhaven, Germany for HL) against EBV-encoded small RNAs (EBER1 and EBER2). C-MYC/IGH translocations were analyzed by fluorescence in situ hybridization using a break-apart probe (Vysis MYC; Abbott, Abbott Park, IL). The studies used formalin-fixed, paraffin-embedded tissue on 22 BLs and 33 HLs.

Yaqo R.T., Jalal S.D., Ghafour K.J., Hassan H.A, & Hughson M.D. (2019). Non-Hodgkin Lymphoma in the Middle East Is Characterized by Low Incidence Rates With Advancing Age. Journal of Global Oncology, 5, JGO.18.00241.

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Assessing BL Latency and Translocations

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BL EBV latency was assessed by chromogenic in situ hybridization (ISH) using the Novocastra (Leica Biosystems, Wetzler, Germany) probe for EBER. C-MYC/IGH translocations were analyzed by fluorescence in situ hybridization using a break-apart probe (Vysis MYC, Abbott Laboratories, Abbott Park, IL). EBER and MYC translocation studies used formalin-fixed, paraffin-embedded tissue of 24 BL.

Muhealdeen D.N., Shwan A., Yaqo R.T., Hassan H.A., Muhammed B.O., Ali R.M, & Hughson M.D. (2022). Epstein-Barr virus and Burkitt’s lymphoma. Associations in Iraqi Kurdistan and twenty-two countries assessed in the International Incidence of Childhood Cancer. Infectious Agents and Cancer, 17, 39.

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