A fiberoptic bronchoscope (BF‐P260F, Olympus, Tokyo, Japan), processor monitor (EU‐ME1; Olympus), ultrasonic host (MAJ‐935, Olympus) and R‐EBUS with a 1.4‐mm diameter (UM‐S20‐17S, Olympus) were used for R‐EBUS. A guiding sheath had (diameter 1.95 mm), and biopsy forceps (diameter 1.5 mm) were used (K‐201, Olympus). Before the interventional surgery, the lesion location was determined using preoperative thin‐layer CT under local infiltration anaesthesia combined with intravenous anaesthesia. A fasting period of 6 h for solid and liquid food was required before the surgery. The heart rate, blood pressure and pulse oxygen levels were monitored throughout the operation, with nasal oxygen provided as necessary to maintain blood oxygen saturation above 90%. During the surgery, the bronchoscope was first delivered to the bronchial lesion site based on CT imaging, and a small ultrasonic probe was inserted into the guide sheath to locate and fix the probe. The visible bronchial segments were continuously examined until a characteristic ultrasound signal indicating the presence of solid lesions was observed (Figure 1B ). Subsequently, the EBUS probe was removed, and the sampling instrument was inserted through the guide sheath to obtain tissue samples.
Maj 935
Manufactured by Olympus
Sourced in Japan
The MAJ-935 is a laboratory equipment product developed by Olympus. It is designed to perform a core function without further interpretation on its intended use.
Automatically generated - may contain errors
Lab products found in correlation
Um s20 17s, by Olympus (4 mentions)
K 201, by Olympus (2 mentions)
Bf p260f, by Olympus (2 mentions)
Maj 1720, by Olympus (2 mentions)
Um 2r, by Olympus (2 mentions)
Eu me1, by Olympus (1 mentions)
Bf f260, by Olympus (1 mentions)
Um 3r, by Olympus (1 mentions)
Gf ue160 al5, by Olympus (1 mentions)
Um dp12 25r, by Olympus (1 mentions)
Um dp20 25r, by Olympus (1 mentions)
Sonovue, by Bracco (1 mentions)
Gf uct260, by Olympus (1 mentions)
Ez shot 3 plus, by Olympus (1 mentions)
Echotip ultra, by Cook Medical (1 mentions)
Echotip procore, by Cook Medical (1 mentions)
9 protocols using maj 935
1
Ultrasound-Guided Bronchial Lesion Biopsy
2
Ultrasound Endoscopy for Lesion Evaluation
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For lesions with the diameter shorter than 2 cm, the ultrasound endoscope mainframe was OLYMPUS EU-ME2 (Olympus Corporation, 7,016,223, Tokyo Metropolis, Japan), the microprobe driver was MAJ-935 (Olympus Corporation, SFDA(I)20,123,232,155, Tokyo Metropolis, Japan), and the probe was UM-3R (20 MHz) (Olympus Corporation, 7,173,855, Tokyo Metropolis, Japan). Besides, the PENTAX Medical ultrasound endoscope (HOYA Corporation, EE012155, Tokyo Metropolis, Japan) was employed for assessing lesions with the diameter over 2 cm, or that could not be displayed clearly by the scanning of the ultrasound small probe, or accompanied with extraluminal growth, with a frequency of 7.5 to 10 MHz. All scans were performed using the water-filling method.
3
R-EBUS-Guided Transbronchial Lung Biopsy
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Electronic video bronchoscope (Olympus BF-F260 or Olympus BF-P-260F, Olympus, Tokyo, Japan), ultrasonic host (MAJ-935, Olympus, Tokyo, Japan), R-EBUS with a 1.4 mm diameter (UM-S20-17S, Olympus, Tokyo, Japan), and Biopsy forceps (JHY-FB-18-105-O-O-A1, Changzhou Jiuhong) were used in performing R-EBUS-guided TBLB or TBLB.
4
Endoscopic Ultrasound Examination Techniques
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Endoscopic ultrasound examination included the use of the EU-ME2 PP ultrasound host (Olympus Japan), MAJ-935 or MAJ-1720 ultrasound probe driver, UM-2R, UM-3R ultrasound microprobe, or the GF-UE160-AL5 radial array scanning endoscope. Ultrasound scanning was performed by the water injection method. The liquid and gas in the gastric cavity were first removed, and the target lesions of ultrasonic scanning were displayed and confirmed. Then, water was slowly injected at a low flow rate, and the lesion was completely immersed in degassed water following suction of gastric air. The micro-probe was taken out of the endoscopic channel for ultrasound scanning, and for larger lesions, a radial scanning ultrasound was used for ultrasound scanning. The following features were recorded: location, size, the presence of mucosal ulceration, shape, original layer, echogenicity, echo uniformity, the presence of marginal halos, cystic change, and calcification.
5
Multimodal Imaging of Hepatic Lesions
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DCEUS examinations were performed with Acuson Seioquoia 512 ultrasound system, equipped with contrast pulse sequencing (CPS) technology; UOCA Xinzhang®(Huqingyutang, HangZhou, China) was made from a soya derivative; Intravenous contrast agent SonoVue (Bracco, Milan, Italy)–a suspension of sulfur hexafluoride microbubbles.
EUS studies were performed with EndoEcho system (Olympus, Japan): Model for the host EU-M2000; endoscopic ultrasonography for the Olympus GF-UM 2000-ring endoscopic ultrasound scan, the department tip diameter of 12.7 mm, pipe pliers diameter of 2.2 mm, scan range of 360°; Olympus UM-DP12-25R, and UM-DP20-25R ultrasonic micro-probe; ultrasonic probe drive MAJ-935; MH-303 bladders (Japan); sterile degassed water (our hospital).
EUS studies were performed with EndoEcho system (Olympus, Japan): Model for the host EU-M2000; endoscopic ultrasonography for the Olympus GF-UM 2000-ring endoscopic ultrasound scan, the department tip diameter of 12.7 mm, pipe pliers diameter of 2.2 mm, scan range of 360°; Olympus UM-DP12-25R, and UM-DP20-25R ultrasonic micro-probe; ultrasonic probe drive MAJ-935; MH-303 bladders (Japan); sterile degassed water (our hospital).
6
Radial EBUS-Guided Bronchial Biopsies
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Bronchoscopy was performed with 2% topical lidocaine and intravenous sedation with midazolam and fentanyl. We used Olympus BF-1T180 bronchoscopes.
Radial EBUS was performed with an endoscopic ultrasound system Olympus EU ME 30; ultrasound probes 20 MHz Olympus UM-S20-17S and MAJ-935 probe driving unit. Procedures were performed by five operators, all with more than 4 years of experience in bronchoscopy. Radial scanning probe was inserted in the airways via flexible bronchoscope. All visible, relevant segments were scanned using ultrasound. If the lesion was visualized, the distance between the bronchoscope inserted in the orifice of the bronchus and the lesions was measured. The EBUS probe was then removed and forceps were introduced through the bronchoscope channel. Biopsies (at least four forceps biopsies) were performed in the same subsegment and at the same distance from the orifice of the bronchus. If the lesion was not visualized, blind forceps, brush, and bronchial wash biopsies were obtained from the relevant lung segments without fluoroscopy.
Radial EBUS was performed with an endoscopic ultrasound system Olympus EU ME 30; ultrasound probes 20 MHz Olympus UM-S20-17S and MAJ-935 probe driving unit. Procedures were performed by five operators, all with more than 4 years of experience in bronchoscopy. Radial scanning probe was inserted in the airways via flexible bronchoscope. All visible, relevant segments were scanned using ultrasound. If the lesion was visualized, the distance between the bronchoscope inserted in the orifice of the bronchus and the lesions was measured. The EBUS probe was then removed and forceps were introduced through the bronchoscope channel. Biopsies (at least four forceps biopsies) were performed in the same subsegment and at the same distance from the orifice of the bronchus. If the lesion was not visualized, blind forceps, brush, and bronchial wash biopsies were obtained from the relevant lung segments without fluoroscopy.
7
Comprehensive EUS Mapping of Lesions
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A EUS probe (UM-2R; Olympus, Tokyo, Japan) and probe driving unit (MAJ-935; Olympus) were initially used to map the lesions. The imaging frequency of the probe was 12 MHz.
EUS was performed by an experienced endosonographer (J.S.R.). All examinations were performed under intravenous sedation using midazolam and propofol. The lesion was scanned after filling the stomach with deaerated water.
DH Kim and HS Lee recorded and reviewed the following EUS features for all lesions: 1) location, 2) gross shape 4 In the S-type, the lesion originated in the second or third layer. In the D-type, the lesion was in the third and fourth layers with or without extension into the fifth layer. Moreover, PM thickening was defined as "PMep/PMnormal ≥2" (Fig. 2).
EUS was performed by an experienced endosonographer (J.S.R.). All examinations were performed under intravenous sedation using midazolam and propofol. The lesion was scanned after filling the stomach with deaerated water.
DH Kim and HS Lee recorded and reviewed the following EUS features for all lesions: 1) location, 2) gross shape 4 In the S-type, the lesion originated in the second or third layer. In the D-type, the lesion was in the third and fourth layers with or without extension into the fifth layer. Moreover, PM thickening was defined as "PMep/PMnormal ≥2" (Fig. 2).
8
EUS-guided Fine Needle Tissue Aspiration for Subepithelial Lesions
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The EUS Probe (UM-2R; Olympus, Tokyo, Japan) and probe driving unit (MAJ-935; Olympus) were used to map the lesion. The image frequency of the probe was 12 MHz. EUS-guided FNTA was performed with a linear array echoendoscope (GF-UCT260; Olympus) and probe driving unit (MAJ-1720; Olympus). Under ultrasound guidance, SETs were punctured with 19-, 20-, 22-, or 25-gauge needles (EchoTip ProCore, Cook Medical Inc, Bloomington, IN; EchoTip Ultra, Cook Medical; EZ Shot3 Plus, Olympus). After visualizing the tip of the catheter, the needle was advanced from the catheter sheath through the wall of the gastrointestinal (GI) tract and into the target lesions under ultrasound guidance. The stylet was removed, and the initial passes were performed by moving the needle back and forth within the target lesion for 15 to 30 seconds. No suction was applied during biopsy unless the biopsy failed to yield any material or if the lesion was cystic.
9
Bronchoscopic Ultrasound-Guided Lung Biopsy
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The procedure was performed using a flexible bronchoscope (4.0 mm outer diameter, 2.0 mm working channel diameter, BF-P290; 2.8 mm outer diameter, 1.2 mm working channel diameter, BF-XP290. Olympus, Tokyo, Japan); Archimedes VBN System (Broncus, CA, United States); ultrasound processor (EU-ME2PP, Olympus, Tokyo, Japan), probe driving unit (MAJ-935, Olympus, Tokyo, Japan), rEBUS probe (UM-S20-17S, 20 MHz, outer diameter 1.7 mm; Olympus, Tokyo, Japan); guide sheath (outer diameter 1.95 mm, K-201; Olympus Tokyo, Japan); C-arm x-ray machine.
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