Overnight fasting blood samples were routinely drawn. Fasting blood glucose, total cholesterol (TC), triglycerides (TG), HDL-C, and LDL-C were measured using an ADVIA-2400 automatic biochemical analyzer (Siemens, Erlangen, Germany) and the triglyceride test kit (GPO-PAP, Shanghai Huachen, Shanghai, China). A BNP II protein analyzer (Siemens, Erlangen, Germany) was used to test serum high-sensitivity CRP (hs-CRP) (C-reactive protein kit, Siemens Healthcare Diagnostics Products GmbH, Erlangen, Germany), glycated hemoglobin (HbA1c) (HBIC HbA1c kit, Siemens Healthcare Diagnostics Products GmbH, Erlangen, Germany), and homocysteine (Hcy) (Hcy kit, Siemens Healthcare Diagnostics Products GmbH, Erlangen, Germany).
Non-HDL-C was calculated by subtracting HDL-C levels from TC. Non-HDL-C levels were classified into two grades according to the criteria recommended by the Patient-centered management of dyslipidemia developed by the NLA in 2015 [7 (link)]: normal group (non-HDL-C <3.4 mmol/l) and high group (non-HDL-C ≥3.4 mmol/l). The high group can be further divided into higher than normal (3.4 mmol/l ≤ non-HDL-C <4.2 mmol/l), critical high (4.2 mmol/l ≤ non-HDL-C <5.0 mmol/l), and very high (non-HDL-C ≥5.0 mmol/l).
Non-HDL-C was calculated by subtracting HDL-C levels from TC. Non-HDL-C levels were classified into two grades according to the criteria recommended by the Patient-centered management of dyslipidemia developed by the NLA in 2015 [7 (link)]: normal group (non-HDL-C <3.4 mmol/l) and high group (non-HDL-C ≥3.4 mmol/l). The high group can be further divided into higher than normal (3.4 mmol/l ≤ non-HDL-C <4.2 mmol/l), critical high (4.2 mmol/l ≤ non-HDL-C <5.0 mmol/l), and very high (non-HDL-C ≥5.0 mmol/l).