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Nrp1 blocking antibody

Manufactured by R&D Systems
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The NRP1 blocking antibody is a laboratory tool used to inhibit the function of the Neuropilin-1 (NRP1) protein. NRP1 is a cell surface receptor involved in various biological processes. The antibody binds to NRP1 and blocks its interaction with other molecules, which can be useful for studying the role of NRP1 in cellular and molecular research.

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Lab products found in correlation

Su1498, by Merck Group (2 mentions) Ve cadherin, by Santa Cruz Biotechnology (2 mentions) P enoss1177, by Cell Signaling Technology (2 mentions) Pvegfr2 y1175, by Cell Signaling Technology (2 mentions) Tvegfr2, by Cell Signaling Technology (2 mentions) Piezo1, by Abcam (2 mentions) T enos, by BD (2 mentions) P vinculiny822, by Abcam (2 mentions) T vinculin, by Merck Group (2 mentions) Integrin αvβ3 clone lm609, by Merck Group (2 mentions) Plxnd1, by Thermo Fisher Scientific (2 mentions) Gq 11, by Santa Cruz Biotechnology (2 mentions) Semaphorin 3e, by R&D Systems (2 mentions) T akt, by Cell Signaling Technology (2 mentions) Pakt s473, by Cell Signaling Technology (2 mentions)

2 protocols using nrp1 blocking antibody

1

VEGFR2 and Semaphorin 3E Signaling

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The antibodies used for western blotting included phospho(p)-ERK1/2T-202;Y-204, total(t)-ERK1/2, pAktS473, tAkt, p-eNOSS1177, pVEGFR2Y1175, tVEGFR2 (all antibodies from Cell Signaling Technology), t-eNOS (BD Biosciences), p-VinculinY822 (AbCam), t-Vinculin (Sigma Aldrich), PI3K/P85 (Upstate), integrin αvβ3 (clone LM609, Merck), Shc (Abcam),VE-cadherin (Santa Cruz), PlxnD1 (Thermo Fisher Scientific and Abcam), Piezo1 (Abcam), Gq/11 (Santa Cruz Biotechnology), Src (Upstate)
The inhibitors used in the study included VEGFR2 tyrosine kinase inhibitor SU1498 (Sigma Aldrich). Recombinant Semaphorin 3E was purchased from R&D Systems (Bio-techne, Minneapolis, MN, USA) and used at 10 μM. NRP1 blocking antibody was purchased from R&D Systems and Sema3E blocking antibody was from Thermo Fisher Scientific USA.
Mehta V., Pang K.L., Rozbesky D., Nather K., Keen A., Lachowski D., Kong Y., Karia D., Ameismeier M., Huang J., Fang Y., del Rio Hernandez A., Reader J.S., Yvonne Jones E, & Tzima E. (2020). The Guidance Receptor Plexin D1 Moonlights as an Endothelial Mechanosensor. Nature, 578(7794), 290-295.
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2

VEGFR2 and Semaphorin 3E Signaling

Check if the same lab product or an alternative is used in the 5 most similar protocols
The antibodies used for western blotting included phospho(p)-ERK1/2T-202;Y-204, total(t)-ERK1/2, pAktS473, tAkt, p-eNOSS1177, pVEGFR2Y1175, tVEGFR2 (all antibodies from Cell Signaling Technology), t-eNOS (BD Biosciences), p-VinculinY822 (AbCam), t-Vinculin (Sigma Aldrich), PI3K/P85 (Upstate), integrin αvβ3 (clone LM609, Merck), Shc (Abcam),VE-cadherin (Santa Cruz), PlxnD1 (Thermo Fisher Scientific and Abcam), Piezo1 (Abcam), Gq/11 (Santa Cruz Biotechnology), Src (Upstate)
The inhibitors used in the study included VEGFR2 tyrosine kinase inhibitor SU1498 (Sigma Aldrich). Recombinant Semaphorin 3E was purchased from R&D Systems (Bio-techne, Minneapolis, MN, USA) and used at 10 μM. NRP1 blocking antibody was purchased from R&D Systems and Sema3E blocking antibody was from Thermo Fisher Scientific USA.
Mehta V., Pang K.L., Rozbesky D., Nather K., Keen A., Lachowski D., Kong Y., Karia D., Ameismeier M., Huang J., Fang Y., del Rio Hernandez A., Reader J.S., Yvonne Jones E, & Tzima E. (2020). The Guidance Receptor Plexin D1 Moonlights as an Endothelial Mechanosensor. Nature, 578(7794), 290-295.
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