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Bp 2000 analysis system

Manufactured by Visitech
Sourced in United States

The BP-2000 Analysis System is a laboratory instrument designed for the analysis of various samples. It performs automated measurements and data processing to provide analytical results. The core function of the BP-2000 is to conduct sample analysis, without further interpretation or extrapolation on its intended use.

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2 protocols using bp 2000 analysis system

1

Systolic Blood Pressure Measurement in Mice

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Systolic blood pressure was measured in trained conscious mice, maintained at normal body temperature, using a BP-2000 Analysis System (Visitech Systems) as previously described (104 (link)). Mice were “trained” to the procedure twice daily for 3 consecutive days, and data were recorded over the following 2 d. Statistical analyses are from 10 readings for each mouse.
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2

Telemetric Bladder Function Assessment

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Mice were anaesthetised with isoflurane (1–5%), and an HDX11 telemeter (Data Sciences International Inc., New Brighton, MN, USA; Figure 2A) implanted subcutaneously via a laparotomy with the pressure line inserted into the bladder and secured by a suture. Animals recovered over 7–10 days with prophylactic antibiotics and analgesics. After recovery, animals were housed in modified metabolic cages where telemeter recordings were obtained through receiving units (RSC-1, Data Sciences International Inc.). Load cells (5 μl/10 Hz sensitivity) below each cage measured the duration and volume of voids, and filter paper recorded voiding patterns. Data were recorded with 12-hour light/dark cycles using LabChart (ADInstruments, Colorado Springs, CO, USA) and OxyMax (Columbus Instruments, Columbus, OH, USA) software. Arterial blood pressure (BP) and heart rate (HR) were measured using a BP-2000 analysis system (Visitech Systems, Apex, NC, USA) before cinaciguat administration and then immediately, 1 h and 2 h after administration. Animals were acclimatised to the procedure for a week before cinaciguat treatment. Decerebrate CMG recordings were conducted as previously described [27 (link)].
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