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Xeleris functional imaging workstation

Manufactured by GE Healthcare
Sourced in United States

The Xeleris Functional Imaging Workstation is a software application designed for the analysis and processing of functional imaging data. It provides tools for image visualization, quantification, and reporting.

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4 protocols using xeleris functional imaging workstation

1

Standardized PET/CT Imaging Protocol

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Fasting for more than 6 hours prior to the FDG PET/CT exam was requested. Blood glucose level was controlled to be less than 150 mg/dl before tracer injection. Patients were asked to lie down comfortably for minimized uptake of skeletal muscles after intravenous injection of F-18 FDG (7 MBq per kilogram) with the 55 ± 5 minutes mean uptake time. With an “arm-up” position, the spiral low dose CT scan with 140 kV, 80 mA and 3.75 mm section thickness was acquired from vertex to mid-thigh. Then the reverse direction emission acquisition (4 minutes/bed position) was conducted. All the FDG PET/CT images were acquired with the Discovery ST 16 PET/CT scanner (GE Medical System, Waukesha, Wisconsin, USA). Using previous CT transmission for attenuation correction, the PET images were reconstructed iteratively (i.e. order subset expectation maximization). The reconstructed images were displayed on the Xeleris Functional Imaging Workstation (GE Medical System, Waukesha, Wisconsin, USA) for interpretation.
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2

Gastric and Esophageal Transit Imaging

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For both gastric emptying and oesophageal transit studies, the radioactive counts were drawn around the oesophagus, neo-stomach (i.e. including proximal and distal stomach) and small bowel; these were defined as the regions of interest (ROI). Normal oesophageal transit was defined as the complete clearance across the esophagogastric junction by progressive antegrade transit without reflux in the 1 min. Delayed transit was defined as any noticeable hold-up of the bolus or evidence of reflux back into the oesophagus. After the 90 min, any residual activity retained in the oesophagus and stomach were quantified using the first 2 min acquisition frame compared to the residual activity in the final 2 min period. Radioactive counts were represented as a function of time in a time-activity curve (TAC) over 60 s (one image per second). The sleeve shapes were classified into three different patterns of intragastric meal distribution: proximal (dilated portion of the proximal sleeve), antral (dilated portion of the antrum), and uniform (tubular-shaped sleeve). All images were processed on a General Electric Xeleris Functional Imaging Workstation.
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3

FDG PET/CT Imaging Protocol for Oncology

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All the FDG PET/CT images were acquired using the Discovery ST 16 PET/CT scanner (GE Medical System, Waukesha, Wisconsin, USA). Every patient was asked to fast for at least 6 hours prior to the examination. The blood glucose level was measured to enssure no more than 150 mg/dl before the tracer injection. After intravenous injection of 370-555 MBq (10-15 mCi) of 18F-FDG, patients were asked to lie comfortably to reduce muscular uptake. The mean uptake time was 55 ± 5 minutes. Spiral low dose CT scan (140 kV, 80 mA, 3.75 mm section thickness) was acquired with a craniocaudal direction and an “arm up” position, followed by the emission acquisition with a reverse direction. The emission scan time per bed was 4 minutes. PET images were reconstructed iteratively (order subset expectation maximization) with CT data for attenuation correction. The Xeleris Functional Imaging Workstation (GE Medical System, Waukesha, Wisconsin, USA) was used for image display and interpretation.
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4

FDG PET/CT Imaging Procedure for Women

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Women who participated in this study fasted for at least 6 hours before undergoing FDG PET/CT imaging. Their serum glucose levels were checked before the injection of the 18 F-FDG radioactive tracer. All women had blood glucose levels < 150 mg/dL at the time of the tracer injection. Each woman received 370-555 MBq (10-15 mCi) of 18 F-FDG, based on her body weight (0.19 mCi/kg). After injecting the radioactive tracer, the woman rested for ˜60 minutes. Whole body FDG PET/CT (Discovery ST-16; GE Healthcare, Milwaukee, WI) was performed from the head to the upper thigh with the woman supine.
Before PET scanning, CT scanning was performed with the following parameters: 0.6 seconds per rotation, 120 kV, 100 mA, and 3.75-mm thick slices. After completing a plain CT, PET images of the same areas were acquired in the two-dimensional mode for 4 minutes per bed position. Attenuation-corrected PET images were reconstructed using an ordered subset expectation maximization iterative reconstructed algorithm. The FDG PET/CT images were reconstructed by the Xeleris functional imaging workstation (GE Healthcare). A standardized uptake value (SUV) was determined semi-automatically on the Xeleris workstation.
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