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Biocel a10

Manufactured by Merck Group
Sourced in United States

Biocel A10 is a laboratory centrifuge designed for general-purpose applications. It is a benchtop model with a fixed-angle rotor that can accommodate multiple sample tubes or microplates. The centrifuge provides precise speed control and consistent sample separation, making it suitable for a variety of laboratory workflows.

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2 protocols using biocel a10

1

Development of Novel DPI Device

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Rifampicin (> 98.0%, lot number: 6K4AF-RO) was ordered from TCI (Tokyo, Japan). With the exception of water, which was purified in-house (Merck-Millipore Biocel A10, Burlington, MA, USA), all solvents were HPLC grade. Oxygen (99.99%), the octafluorocyclobutane (OFCB) (99.99%), and nitrogen (N 2 ) (99.99%) gases were purchased from Air Liquide (Paris, France), and hexamethlydisiloxane (HMDSO) was ordered from Sigma-Aldrich (St. Louis, MO, USA). Polyamide (PA) plastic material used to develop the plasma processes was kindly provided by Hadi-Plast (Hadi-Plast GmbH & Co. KG, Hövelhof, Germany). The Presspart prototype DPI (PP DPI) tested was provided by Heitkamp & Thumann Ltd. (Blackburn, UK). The set-up of this novel DPI was described and explained in a previous study [32] .
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2

Characterization of Albuterol Sulfate Dry Powder Inhalers

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The albuterol sulfate–alpha lactose monohydrate formulation (Cyclocaps®) (PB Pharma GmbH, Meerbusch, Germany) was purchased from a pharmacy. For spray-drying, rifampicin and amoxicillin were ordered from TCI (Tokyo, Japan). Except for water, which was purified in-house (Merck-Millipore Biocel A10, Burlington, MA, USA), all other solvents were HPLC grade. Inhalac 251® was a kind gift from MEGGLE GmbH & Co. KG (Wasserburg am Inn, Germany). The Lupihaler® devices (Lupin Limited, Mumbai, India) were purchased from a pharmacy in India. The Handihaler® and Presspart prototype DPI inhalers were gifts from Boehringer Ingelheim (Ingelheim am Rhein, Germany) and H&T Presspart (Blackburn, United Kingdom), respectively.
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