Antifungals

Manufactured by Merck Group

Sourced in United States, Germany

Antifungals are laboratory equipment used to identify and study fungal organisms. They provide essential tools for the detection, analysis, and examination of fungal species in various research and diagnostic applications.

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Lab products found in correlation

Bradford reagent, by Merck Group (1 mentions) Dulbecco modified eagle medium (dmem), by Merck Group (1 mentions) Glutamine, by Merck Group (1 mentions) Pnfkb, by Cell Signaling Technology (1 mentions) 2 thiobarbituric acid, by Merck Group (1 mentions) Pbs buffer, by Lonza (1 mentions)

Spelling variants of this product

Antifungal drugs (5 citations) Antibiotic/antifungal solution (5 citations) Antibiotics/antifungals (2 citations) Reference antibacterial and antifungal compounds (2 citations) Penicillin-streptomycin antibiotic antifungal cocktail (2 citations) Antibiotic/antifungal (2 citations)

2 protocols using antifungals

Antifungal Susceptibility of C. haemulonii

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Due to the clinical origin of both strains and their relatedness to the multidrug resistant members of the C. haemulonii complex, their in vitro antifungal susceptibility was determined by the broth dilution method using the European Committee on Antimicrobial Susceptibility Testing (EUCAST) protocol.²¹ Antifungals were obtained from Sigma–Aldrich (St. Louis, MI, USA). Included in this test were: amphotericin B (AMB), anidulafungin (ANI), micafungin (MCF), 5-flucytosine (5FC), and various azoles including fluconazole (FLU), itraconazole (ITR), voriconazole (VOR), posaconazole (POS), and isavuconazole (ISA). The concentrations tested ranged between 0.03 and 16 μg/ml for all drugs, except fluconazole (0.125–64 μg/ml). MIC values were determined after 24 h and 48 h.

de Jong A.W., Al-Obaid K., Mohd Tap R., Gerrits van den Ende B., Groenewald M., Joseph L., Ahmad S, & Hagen F. (2023). Candida khanbhai sp. nov., a new clinically relevant yeast within the Candida haemulonii species complex. Medical Mycology, 61(2), myad009.

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Bioactive Glass Synthesis and Characterization

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The substances used for synthesizing the bioactive glasses (H₃BO₃, CaF₂, and V₂O₅), along with the Bradford reagent, 2-thiobarbituric acid, glutamine, DMEM, 10% fetal bovine serum (FBS), hydrocortisone, antibiotics, and antifungals were purchased from Sigma Aldrich, GmbH (Darmstadt, Germany). PBS buffer was acquired from Lonza (Brussels, Belgium) and standard Ca²⁺ solutions from Fluka (Frankfurt, Germany). Phosphorylated histone H₂AX (pS139; γH₂AX) was purchased from Stressgen Bioreagents Corporation (Victoria, BC, Canada). Antibodies against nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) and pNF-KB were obtained from Cell Signaling Technology, Inc. (Danvers, MA, USA) and glyceraldehyde 3-dehydrogenase (GAPDH) was acquired from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

Clichici A., Filip G.A., Achim M., Baldea I., Cristea C., Melinte G., Pana O., Tudoran L.B., Dudea D, & Stefan R. (2022). Characterization and In Vitro Biocompatibility of Two New Bioglasses for Application in Dental Medicine—A Preliminary Study. Materials, 15(24), 9060.

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