Activc

Manufactured by B. Braun

Sourced in Germany

ActivC is a laboratory equipment product designed for cell culture applications. It serves as a cell culture incubator, providing a controlled environment for cell growth and maintenance.

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Lab products found in correlation

4 protocols using activc

Cervical Radiculopathy Treatment Comparison

Cited 1 time

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A prospective, randomized double-blind multicenter trial among patients with cervical radiculopathy due to single-level disc herniation was conducted. Patients were randomly assigned into three groups: anterior cervical discectomy with arthroplasty (ACDA; activC, Aesculap AG, Tuttlingen, Germany), anterior cervical discectomy with fusion (ACDF; Cage standalone) and anterior cervical discectomy without fusion (ACD). The design and study protocol were published previously.13 (link) The protocol was approved by medical ethics committees, including an approval for randomization after anesthetic induction. All patients gave informed consent. The 2-year follow-up data revealed no differences in clinical outcomes.14 (link)

Yang X., Donk R., Arts M.P., Bartels R.H, & Vleggeert-Lankamp C.L. (2020). Prosthesis in Anterior Cervical Herniated Disc Approach Does Not Prevent Radiologic Adjacent Segment Degeneration. Spine, 45(15), 1024-1029.

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Comparing Cervical Disc Interventions

Cited 1 time

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A prospective, randomized double-blind multicenter trial among patients with cervical radiculopathy due to single level disc herniation was conducted. Patients were randomly assigned into three groups: anterior cervical discectomy with arthroplasty (ACDA; activC, Aesculap AG, Tuttlingen, Germany), anterior cervical discectomy with fusion (ACDF; Cage standalone), and anterior cervical discectomy without fusion (ACD). The protocol was approved by medical ethics committees, including an approval for randomization after anesthetic induction. All patients gave informed consent. The design and study protocol were published previously.^{25 (link)}

Yang X., Donk R., Bartels R.H., Arts M.P., Depreitere B, & Vleggeert-Lankamp C.L. (2020). Comparing Heterotopic Ossification in Two Cervical Disc Prostheses. Spine, 45(19), 1329-1334.

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ActivC Artificial Cervical Disc Characteristics

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The investigational device used in the ACDA group was the ActivC flat artificial cervical disc (Aesculap AG, Tuttlingen, Germany). The ActivC device is composed of two flat Cobalt-Chrome-Molybden alloy metal endplate components with spikes on the superior endplate, an inferior endplate and a keel for primary stability. The inferior prosthesis plate has an integrated polyethylene inlay. The implants are available in six different sizes (XS, S, M, L, XL and XXL) and in three heights (5, 6, and 7 mm).

Goedmakers C.M.W., de Vries F., Bosscher L., Peul W.C., Arts M.P, & Vleggeert-Lankamp C.L.A. (2023). Long-term results of the NECK trial-implanting a disc prosthesis after cervical anterior discectomy cannot prevent adjacent segment disease: five-year clinical follow-up of a double-blinded randomised controlled trial. The spine journal : official journal of the North American Spine Society, 23(3).

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Cervical Radiculopathy Treatment Comparison

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A prospective, randomized double-blind multicentre trial among patients with cervical radiculopathy due to single-level disc herniation was conducted. Patients were randomly assigned into three groups: anterior cervical discectomy with arthroplasty (ACDA; activ ® C, Aesculap AG, Tuttlingen, Germany), anterior cervical discectomy with fusion (ACDF; Cage standalone) and anterior cervical discectomy (ACD). The protocol was approved by medical ethics committees, including an approval for randomization after anaesthetic induction. All patients gave informed consent.
The design and study protocol were published previously [13] (link). The 2-year follow-up data revealed no differences in clinical outcomes [14] (link).

Yang X., Bartels R.H.M.A., Donk R., Arts M.P., Goedmakers C.M.W, & Vleggeert-Lankamp C.L.A. (2020). The association of cervical sagittal alignment with adjacent segment degeneration. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 29(11).

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