Lcms 2010 ev spectrometer

Melting points were measured on a Boetius apparatus and are uncorrected. IR spectra were taken in KBr pellets on a Nicolet 380 FTIR 1600 spectrometer. Elemental analyses were performed on a Vario El Cube CHNS analyzer and the results are within ±0.4%. NMR spectra were recorded on a Varian Gemini 200, a Varian Unity 500, or a Bruker Avance III HD apparatus. ¹H and ¹³C chemical shifts were measured relative to the residual solvent signal at 7.26 ppm and 77.0 (CDCl₃) or 2.50 ppm and 39.5 ppm (DMSO-d₆). Coupling constants are shown in hertz (Hz). The mass spectra were recorded on a Shimadzu LCMS-2010 EV spectrometer equipped with an electrospray source. ESI-MS spectra were registered in a positive- or negative-ion mode. Preparative thin layer chromatography was performed on silica gel 60 PF₂₅₄ containing gypsum (Merck KGaA, Darmstadt, FRG) with the aid of Chromatotron^® using the reported solvent systems. 2-Chloroquinoline-3-carbaldehyde (1) was obtained according to the published method [57 (link)]. UV-Vis spectra were recorded with an Analytik Jena Spekol 1200 (Analytik Jena AG, Jena, Germany) in a 1.0 cm cuvette maintained at 37 °C by a thermostatically controlled cuvette holder.