The X-ray diffraction (XRD) patterns were obtained with a RIGAKU, Tokyo, Japan D/MAR-2500 powder X-ray diffraction in the 2θ range from 10° to 80°. The reference data were taken from the ICSD (Inorganic Crystal Structure Database). Scanning electron microscope (SEM) and Energy-dispersive X-ray spectroscopy (EDS) characterization were performed by a JEOL Ltd., Tokyo, Japan JSM-6700F field emission SEM.
Fluorescence measurement was carried out at room temperature with F-4600 fluorescence spectrometer (Hitachi Ltd., Tokyo, Japan). Excitation and emission spectra were corrected for instrumental response. For the upconversion measurements, the solid-state 980 nm laser was used as the excitation source. Magnetic properties were performed using a 1.5 T MRI system (Bruker, Billerica, Massachusetts, Germany mq60 NMR analyzer) at 300 K. Ultraviolet–visible–NIR spectrophotometer (Cary500; Varian Inc., Palo Alto, California, USA) was used to investigate the loading of MC540 and DOX onto the YbPO4:Er,Dy microspheres.
Fluorescence measurement was carried out at room temperature with F-4600 fluorescence spectrometer (Hitachi Ltd., Tokyo, Japan). Excitation and emission spectra were corrected for instrumental response. For the upconversion measurements, the solid-state 980 nm laser was used as the excitation source. Magnetic properties were performed using a 1.5 T MRI system (Bruker, Billerica, Massachusetts, Germany mq60 NMR analyzer) at 300 K. Ultraviolet–visible–NIR spectrophotometer (Cary500; Varian Inc., Palo Alto, California, USA) was used to investigate the loading of MC540 and DOX onto the YbPO4:Er,Dy microspheres.