Thirty subjects (63.6 ± 4.2 years old) with 15 PD patients (64.2 ± 4.5 years old, 7 female, 8 male) and 15 health controls (62.9 ± 3.8 years old, 6 female, 9 male) were scanned both on MRI and PET scanners. MRI data were collected on the same 3.0 T GE 750 Medical Systems and PET images were acquired using a Siemens Biograph 64 PET/CT scanner (Siemens, Munich, Germany) in 3D mode. A CT transmission scan was first performed for attenuation correction. For dopaminergic imaging, the distribution of dopamine transporter was measured 60 min after the intravenous injection of 370 MBq of 11C‐CFT and lasted for 15 min. The image volume consisted of 148 axial images, with a matrix size of 168 × 168 covering a FOV of 342 × 342 mm2.
Biograph 64 pet ct scanner
Manufactured by Siemens
Sourced in Germany
The Biograph 64 PET/CT scanner is a medical imaging device that combines positron emission tomography (PET) and computed tomography (CT) technologies. The system is designed to acquire high-quality images for diagnostic and clinical applications.
Automatically generated - may contain errors
Lab products found in correlation
Biograph mct scanner, by Siemens (3 mentions)
Imeron 350, by Bracco (3 mentions)
Ge 750 medical systems, by GE Healthcare (1 mentions)
Omnipaque, by GE Healthcare (1 mentions)
Ge discovery pet ct 690, by GE Healthcare (1 mentions)
Gemini tf 64 pet ct scanner, by Philips (1 mentions)
Ge discovery 710, by GE Healthcare (1 mentions)
Discovery 710 scanner, by GE Healthcare (1 mentions)
Biograph mct, by Siemens (1 mentions)
15 protocols using biograph 64 pet ct scanner
1
Dopaminergic Imaging in Parkinson's Disease
2
Prostate Cancer Staging and Restaging with 68Ga-PSMA PET/CT
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A total of 764 patients (mean age, 68 y; range, 48-85) who had undergone 68 Ga-PSMA PET/CT from 2013 to 2016 for known PC (73 for staging and 691 for restaging) were included. This single-center retrospective study was approved by the Institutional Human Research Ethics Committee, with a waiver of informed consent of patients who had been scanned for clinical indications. 68 Ga-PSMA PET/CT Image Acquisition and Protocol 68 Ga was eluted from a 68 Ga/ 68 Ge generator (Isotope Technology Group) and compounded with hydroxybenzylethylenediamine diacetic acid (HBED)-PSMA11 (Advanced Biochemical Compounds). PET images were acquired approximately 60 min (range, 40-85) after injection of 68 Ga-HBED-PSMA11 at 2 MBq/kg (166 MBq; range, 91-246). Acquisition was performed on a GE Discovery PET/CT 690 or 710 scanner (GE Healthcare) or a Siemens Biograph 64 PET/CT scanner (Siemens Healthcare). CT was performed either with a low-dose noncontrast technique (old protocol) or 10 min (range, [8] [9] [10] [11] [12] [13] [14] [15] after intravenous injection of 50 mL of iohexol (Omnipaque [GE Healthcare]; 300 g/mL) contrast medium for optimal ureteral enhancement (new protocol as of mid-2015).
3
PET/CT Imaging Protocol for FDG Uptake
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PET/CT imaging was performed using a Biograph 64 PET/CT scanner (Siemens AG, Munich, Germany). Prior to 18F-FDG PET/CT, all patients were instructed not to eat for ≥6 h to maintain their serum glucose levels at <11.1 mmol/l prior to injection. Image acquisition started ~1 h (mean, 56±2 min; range, 50–60 min) following intravenous injection of FDG (3.7 megabecquerel/kg). The lowest possible milliampere setting on the scanner was used to acquire the CT scans for attenuation correction. The whole-body CT imaging was performed from the skull to the upper part of the thigh with 120 kV, 0.5 sec rotation, 3 mm slice thickness and 0.8 mm intervals. The PET scans were obtained immediately following the whole-body CT scan, including 5–7 bed positions (1.5 min acquisition time per bed position) over the same range as the CT scan. Prior to PET/CT imaging, the serum thyrotropin (TSH) levels of patients were maintained at 30 mU/l.
4
18F-PSMA-1007 PET/CT Imaging Protocol
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All patients gave written informed consent to undergo 18F-PSMA-1007 PET/CT. A median activity of 246 MBq (209–294 MBq) 18F-PSMA-1007 was injected intravenously in line with previously reported radiosynthesis and administration procedures [19 (link)]. Additionally, the patients were simultaneously premedicated with furosemide (20 mg) if no contraindication was given [20 (link)]. The radiopharmaceutical was used on an individual patient basis according to the German Pharmaceuticals Act §13(2b). PET was performed from the skull base to the mid-thigh using a Biograph 64 PET/CT scanner or a Biograph mCT scanner (Siemens Healthineers, Erlangen, Germany) 60 min after tracer injection PET/CT, and included a diagnostic, contrast-enhanced CT scan in a portal-venous phase (Imeron 350; 1.5 mL/kg body weight; Bracco Imaging, Milano, Italy). PET was acquired with 2.5 min per bed position and reconstructed iteratively using TrueX (three iterations, 21 subsets) with Gaussian post-reconstruction smoothing (2 mm full width at half-maximum).
5
Standardized 18F-FDG PET/CT Imaging Protocol
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The patients prepared by fasting for at least 4 hours and controlling a blood glucose level of less than 8 mmol/L before an intravenous administration of 18F‐FDG (0.1–0.2 mCi/kg). The 18F‐FDG PET/CT was performed in a three‐dimensional mode with a scanning range from the skull base to the symphysis pubis using a Siemens Biograph 64 PET/CT scanner 60 min after injection. A low‐dose CT scan was acquired for attenuation and scatter correction and colocalization of radiologically equivalent interpretation.
6
Whole-Body FDG-PET Screening for Malignant Tumors
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The study included a total of 500 patients (287 males and 213 females, age 61.3 ± 17.0 years [mean ± SD]) who underwent a whole-body FDG-PET examination for the screening of malignant tumors between January and May 2016 at our institute. All MIP images were acquired using either a GEMINI TF64 PET-CT scanner (Philips Healthcare, Cleveland, OH, USA), or a Biograph64 PET-CT scanner (Siemens Healthcare, Erlangen, Germany). This study was approved by our institute's Ethics Committee [#017-0365].
7
Same-Day Rest-Stress PET-MPI with 82Rb
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All patients underwent same-day, rest and pharmacological stress PET-MPI study using 82Rb with a Biograph 64 PET/CT scanner (Siemens Healthcare, Erlangen, Germany) or GE Discovery 710 (GE Healthcare, Waukesha, Wisconsin) scanner. A 6-min rest list-mode acquisition was started immediately before the injection of weight-based doses of 925–1850 MBq (25–50 mCi) of 82Rb. Pharmacologic stress was performed, and a 6-min stress imaging acquisition was simultaneously initiated with the start of the 82Rb administration. A low-dose helical CT was acquired prior to each rest and stress PET scanning for attenuation correction as previously described [8 (link)].
8
TSPO PET Protocol for Tumor Imaging
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TSPO PET was performed on a Biograph-64 PET/CT scanner (Siemens Healthineers). The TSPO radioligand [18F]GE-180 was synthesized as previously described (4 (link)). [18F]GE-180 was intravenously injected (181 ± 17 MBq). Low-dose CT was performed for attenuation correction. PET emission data were recorded 60–80 min after injection, and the summation images taken 60–80 min after injection were used for image analyses. Reconstruction parameters were applied as previously described (4 (link)). For evaluation of PET images, tumoral SUVmax was assessed.
9
HRCT Imaging Protocol for PET-CT Scans
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The HRCT scans were obtained using a Siemens Biograph 64 PET-CT scanner. The scanner was used in a helical mode with 64 slices per rotation, 0.6 mm collimation, a pitch of 1, 120 kV peak, and 80 mA. The image reconstruction was done using the B31 kernel with a slice thickness of 0.75 mm, 0.5 mm slice increment and 0.25 mm overlap (as recommended by VIDA Diagnostics, IA, USA).
10
Multimodal 82Rb PET-MPI Stress Testing
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Same-day, rest, and pharmacologic stress 82 Rb PET-MPI studies were performed for all patients on a Biograph 64 PET/CT scanner (Siemens Healthineers) or a Discovery 710 scanner (GE Healthcare). A 6-min rest list-mode acquisition was started immediately before the injection of weight-based doses of 10-12 MBq/kg of 82 Rb (925-1,850 MBq ). Pharmacologic stress with regadenoson, adenosine, or dipyridamole was performed, and a 6-min stress imaging acquisition was simultaneously initiated with the start of the 82 Rb infusion (10-12 MBq/kg). A low-dose helical CT scan was acquired before each rest and stress PET scan for attenuation correction as previously described (11) .
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