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Silencer select sirnas targeting

Manufactured by Thermo Fisher Scientific
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Silencer Select siRNAs targeting is a laboratory product designed for gene silencing applications. The core function of this product is to provide short interfering RNA (siRNA) molecules that can be used to selectively target and silence specific genes of interest in experimental settings. The siRNAs are designed and synthesized to ensure specificity and efficiency in gene knockdown.

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Lab products found in correlation

Lipofectamine rnaimax, by Thermo Fisher Scientific (2 mentions)

Close spelling variants of this product

Silencer Select siRNAs (565 citations) Silencer Select (341 citations) SiRNAs (258 citations) Silencer siRNA (37 citations) SiRNA targeting (8 citations) Silencer select siRNA targeting (3 citations)

2 protocols using silencer select sirnas targeting

1

Silencing PRMT5 and FUS with siRNA

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Silencer Select siRNAs targeting PRMT5 (ID: s20375 and s20377) and FUS (ID: s5401 and s533595) were purchased from Invitrogen. All Stars negative control siRNA was purchased from Qiagen. siRNA transfection was conducted using Lipofectamine RNAiMAX (Invitrogen).
Lin C.C., Chang T.C., Wang Y., Guo L., Gao Y., Bikorimana E., Lemoff A., Fang Y.V., Zhang H., Zhang Y., Ye D., Soria-Bretones I., Servetto A., Lee K.M., Luo X., Otto J.J., Akamatsu H., Napolitano F., Mani R., Cescon D.W., Xu L., Xie Y., Mendell J.T., Hanker A.B, & Arteaga C.L. (2024). PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer. Nature Communications, 15, 2287.
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2

PRMT5 and FUS Silencing Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Silencer Select siRNAs targeting PRMT5 (ID: s20375 and s20377) and FUS (ID: s5401 and s533595) were purchased from Invitrogen. All Stars negative control siRNA was purchased from Qiagen. siRNA transfection was conducted using Lipofectamine RNAiMAX (Invitrogen).
Lin C.C., Chang T.C., Wang Y., Guo L., Gao Y., Bikorimana E., Lemoff A., Fang Y.V., Zhang H., Zhang Y., Ye D., Soria-Bretones I., Servetto A., Lee K.M., Luo X., Otto J.J., Akamatsu H., Napolitano F., Mani R., Cescon D.W., Xu L., Xie Y., Mendell J.T., Hanker A.B, & Arteaga C.L. (2023). Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer. Research Square.
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