All animal procedures were approved by the Institutional Animal Care and Use Committee of the University of Rochester. Female and male mice were bred and maintained in pathogen-free conditions in group housing, used between 6-14 weeks of age, and euthanized in accordance with the University of Rochester guidelines. B6(Cg)-Tyrc-2J/J (Albino B6) mice, OVA-specific OT-II TCR transgenic C57BL/6 mice, B6.PL-Thy1a/CyJ (B6 Thy1.1) and Cxcr3tm1Dgen/J (B6 CXCR3 KO) mice were purchased from The Jackson Laboratory. REX3 (Reports the Expression of CXCR3 ligands) B6 mice were provided by A. Luster, Massachusetts General Hospital. WT C57BL/6 mice were purchased from the National Cancer Institute, Bethesda, MD. REX3 mice were crossed to Albino B6 mice. OT-II TCR transgenic mice were crossed to CXCR3 KO mice. Kaede transgenic mice were obtained from RIKEN.
Cxcr3tm1dgen j b6 cxcr3 ko
Manufactured by Jackson ImmunoResearch
The Cxcr3tm1Dgen/J (B6 CXCR3 KO) is a mouse strain that has a targeted mutation in the Cxcr3 gene, resulting in a knockout of the CXCR3 protein. This strain is on a C57BL/6J genetic background.
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2 protocols using cxcr3tm1dgen j b6 cxcr3 ko
1
Transgenics for Immune Cell Tracking
2
Transgenics for Immune Cell Tracking
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All animal procedures were approved by the Institutional Animal Care and Use Committee of the University of Rochester. Female and male mice were bred and maintained in pathogen-free conditions in group housing, used between 6-14 weeks of age, and euthanized in accordance with the University of Rochester guidelines. B6(Cg)-Tyrc-2J/J (Albino B6) mice, OVA-specific OT-II TCR transgenic C57BL/6 mice, B6.PL-Thy1a/CyJ (B6 Thy1.1) and Cxcr3tm1Dgen/J (B6 CXCR3 KO) mice were purchased from The Jackson Laboratory. REX3 (Reports the Expression of CXCR3 ligands) B6 mice were provided by A. Luster, Massachusetts General Hospital. WT C57BL/6 mice were purchased from the National Cancer Institute, Bethesda, MD. REX3 mice were crossed to Albino B6 mice. OT-II TCR transgenic mice were crossed to CXCR3 KO mice. Kaede transgenic mice were obtained from RIKEN.
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